Translocation as a means of disseminating lipid hydroperoxide-induced oxidative damage and effector action.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Free Radical Biology & Medicine

• Publication date

  2008-03-15

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.freeradbiomed.2007.12.004PMID 18206663PMCID PMC2361152
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome.

  2007cited by this paper
• Hydrogen peroxide sensing and signaling.

  2007cited by this paper
• Thioredoxin and Related Molecules–From Biology to Health and Disease

  2007cited by this paper
• Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis

  2007cited by this paper
• Identification and characterization of a selenoprotein family containing a diselenide bond in a redox motif

  2007cited by this paper
• Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products.

  2007cited by this paper
• The relevance of mitochondrial membrane topology to mitochondrial function.

  2006cited by this paper
• Membrane transport of hydrogen peroxide.

  2006cited by this paper
• Spatially Resolved Cellular Responses to Singlet Oxygen

  2006cited by this paper
• Hydrogen Peroxide: A Signaling Messenger

  2006cited by this paper
• The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation

  2006cited by this paper
• Oxidized phosphatidylserine–CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

  2006cited by this paper
• Intracellular Dissemination of Peroxidative Stress

  2006cited by this paper
• Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling.

  2005cited by this paper
• Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

  2005cited by this paper
• Keratinocytes act as a source of reactive oxygen species by transferring hydrogen peroxide to melanocytes.

  2005cited by this paper
• Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

  2005cited by this paper
• The Inner Mitochondrial Membrane Has Aquaporin-8 Water Channels and Is Highly Permeable to Water*

  2005cited by this paper
• Glutaredoxins: Glutathione-Dependent Redox Enzymes with Functions Far Beyond a Simple Thioredoxin Backup System

  2004cited by this paper
• Protective mechanisms against peptide and protein peroxides generated by singlet oxygen.

  2004cited by this paper
• Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis?

  2004cited by this paper
• The Plasma Membrane Is the Site of Selective Phosphatidylserine Oxidation During Apoptosis: Role of Cytochrome c

  2004cited by this paper
• Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides.

  2004cited by this paper
• The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis.

  2004cited by this paper
• Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

  2004cited by this paper
• Secondary Reactive Oxygen Species Extend the Range of Photosensitization Effects in Cells: DNA Damage Produced Via Initial Membrane Photosensitization ¶ †

  2003cited by this paper
• Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria

  2003cited by this paper
• Secondary Reactive Oxygen Species Extend the Range of Photosensitization Effects in Cells: DNA Damage Produced Via Initial Membrane Photosensitization¶,†

  2003cited by this paper
• Singlet oxygen-mediated damage to proteins and its consequences.

  2003cited by this paper
• Cellular response to oxidative stress: Signaling for suicide and survival *

  2002cited by this paper
• Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.

  2002cited by this paper
• Sterol carrier protein-2: structure reveals function

  2002cited by this paper
• Role of Glutaredoxin in Metabolic Oxidative Stress

  2002cited by this paper
• Thioredoxin Promotes ASK1 Ubiquitination and Degradation to Inhibit ASK1-Mediated Apoptosis in a Redox Activity-Independent Manner

  2002cited by this paper
• Spontaneous transfer of phospholipid and cholesterol hydroperoxides between cell membranes and low-density lipoprotein: assessment of reaction kinetics and prooxidant effects.

  2002cited by this paper
• A Role for Oxidative Stress in Apoptosis: Oxidation and Externalization of Phosphatidylserine Is Required for Macrophage Clearance of Cells Undergoing Fas-Mediated Apoptosis1

  2002cited by this paper
• Hydrogen peroxide as second messenger in lymphocyte activation

  2002cited by this paper
• Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms.

  2001cited by this paper
• Spontaneous intermembrane transfer of various cholesterol-derived hydroperoxide species: kinetic studies with model membranes and cells.

  2001cited by this paper
• Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA

  2001cited by this paper
• Hyperresistance to cholesterol hydroperoxide-induced peroxidative injury and apoptotic death in a tumor cell line that overexpresses glutathione peroxidase isotype-4.

  2001cited by this paper
• Gene structure, intracellular localization, and functional roles of sterol carrier protein-2.

  2001cited by this paper
• Role of Glutathione S-Transferases in Protection against Lipid Peroxidation

  2001cited by this paper
• Dissemination of peroxidative stress via intermembrane transfer of lipid hydroperoxides: model studies with cholesterol hydroperoxides.

  2000cited by this paper
• Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis.

  2000cited by this paper
• Leukocytes utilize myeloperoxidase-generated nitrating intermediates as physiological catalysts for the generation of biologically active oxidized lipids and sterols in serum.

  1999cited by this paper
• Scavenger Receptor BI Mediates the Selective Uptake of Oxidized Cholesterol Esters by Rat Liver*

  1999cited by this paper
• Radiolabeled cholesterol as a reporter for assessing one-electron turnover of lipid hydroperoxides.

  1999cited by this paper
• Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status.

  1999cited by this paper
• Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

  1998cited by this paper
• Lipid hydroperoxide generation, turnover, and effector action in biological systems.

  1998cited by this paper
• Phospholipid transfer proteins revisited.

  1997cited by this paper
• Reaction of phosphatidylcholine hydroperoxide in human plasma: the role of peroxidase and lecithin:cholesterol acyltransferase.

  1996cited by this paper
• Increased selective uptake in vivo and in vitro of oxidized cholesteryl esters from high-density lipoprotein by rat liver parenchymal cells.

  1996cited by this paper
• The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide.

  1995cited by this paper
• Enhanced Levels of Lipoperoxides in Low Density Lipoprotein Incubated with Murine Fibroblasts Expressing High Levels of Human 15-Lipoxygenase (*)

  1995cited by this paper
• Mechanisms of free radical oxidation of unsaturated lipids

  1995cited by this paper
• Sterol carrier protein-2 stimulates intermembrane sterol transfer by direct membrane interaction.

  1995cited by this paper
• Exchange of oxidized cholesteryl linoleate between LDL and HDL mediated by cholesteryl ester transfer protein.

  1995cited by this paper
• Diversity of glutathione peroxidases.

  1995cited by this paper
• Cholesterol interaction with recombinant human sterol carrier protein-2

  1995cited by this paper
• Hydrogen peroxide and the proliferation of BHK-21 cells.

  1995cited by this paper
• High-performance liquid chromatography with mercury cathode electrochemical detection: application to lipid hydroperoxide analysis.

  1995cited by this paper
• Involvement of preexisting lipid hydroperoxides in Cu(2+)-stimulated oxidation of low-density lipoprotein.

  1994cited by this paper
• Greater selective uptake by Hep G2 cells of high-density lipoprotein cholesteryl ester hydroperoxides than of unoxidized cholesteryl esters.

  1993cited by this paper
• Polyunsaturated fatty acid alkoxyl radicals exist as carbon-centered epoxyallylic radicals: a key step in hydroperoxide-amplified lipid peroxidation.

  1993cited by this paper
• Spontaneous lipid transfer between organized lipid assemblies.

  1992cited by this paper
• Phospholipid transfer proteins.

  1991cited by this paper
• Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation.

  1990cited by this paper
• Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides.

  1990cited by this paper
• Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

  1989cited by this paper
• Superoxide anion participation in human monocyte-mediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin.

  1989cited by this paper
• Mechanisms and consequences of cellular cholesterol exchange and transfer.

  1987cited by this paper
• Lipid Exchange: Transmembrane Movement, Spontaneous Movement, and Protein-Mediated Transfer of Lipids and Cholesterol

  1987cited by this paper
• Biochemistry of oxidative stress

  1986cited by this paper
• Free radicals in biology and medicine

  1985cited by this paper
• Sterol carrier and lipid transfer proteins.

  1985cited by this paper
• Oxygen Radicals in Chemistry and Biology

  1985cited by this paper
• Lipid transfer proteins.

  1984cited by this paper
• Oxygen radicals in chemistry and biology: Eds. W. Bors, M. Saran and D. Tait. W. de Gruyter and Co. Berlin, New York, 1984, DM 250, $ 114

  1984cited by this paper
• Sterol metabolism. 23. Cholesterol oxidation by radiation-induced processes.

  1973cited by this paper
• Sterol metabolism. XXV. Cholesterol oxidation by singlet molecular oxygen.

  1973cited by this paper
• Current Topics in Membranes and Transport

  1970cited by this paper
• Mechanisms of Photosensitized Oxidation

  1968cited by this paper
• Mechanisms of photosensitized oxidation. There are several different types of photosensitized oxidation which may be important in biological systems.

  1968cited by this paper
• Zur photosensibilisierten Autoxydation der Steroide. Darstellung von Steroid‐Hydroperoxyden Mittels Phototoxischer Photosensibilisatoren

  1957cited by this paper

• Beyond light scattering: the effects of intralipid on benzoporphyrin derivative-sensitized photodynamic treatment in ovarian cancer cells

  2025cites this paper
• Multifaceted interplays between the essential players and lipid peroxidation in ferroptosis.

  2025cites this paper
• Trafficking of oxidative stress-generated lipid hydroperoxides: pathophysiological implications

  2023cites this paper
• CYP2E1 overexpression protects COS-7 cancer cells against ferroptosis

  2023cites this paper
• Photosensitized Lipid Oxidation: Mechanisms and Consequences to Health Sciences

  2022cites this paper
• Anti-steroidogenic effects of cholesterol hydroperoxide trafficking in MA-10 Leydig cells: Role of mitochondrial lipid peroxidation and inhibition thereof by selenoperoxidase GPx4.

  2022cites this paper
• Electrophilic oxysterols: generation, measurement and protein modification

  2021cites this paper
• From Inert Storage to Biological Activity—In Search of Identity for Oxidized Cholesteryl Esters

  2020cites this paper
• Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting.

  2020cites this paper
• Stopping Membrane-Enveloped Viruses with Nanotechnology Strategies: Toward Antiviral Drug Development and Pandemic Preparedness.

  2020cites this paper
• Upstream signaling events leading to elevated production of pro-survival nitric oxide in photodynamically-challenged glioblastoma cells.

  2019cites this paper
• Understanding membrane remodelling initiated by photosensitized lipid oxidation.

  2019cites this paper
• The intracellular redox environment modulates the cytotoxic efficacy of single and combination chemotherapy in breast cancer cells using photochemical internalisation

  2019cites this paper
• Cholesterol Peroxidation as a Special Type of Lipid Oxidation in Photodynamic Systems

  2018cites this paper
• Insight from Molecular dynamic simulation of reactive oxygen species in oxidized skin membrane

  2018cites this paper
• Spatially Resolved Experiments to Monitor the Singlet Oxygen Initiated Oxidation of Lipid Droplets in Emulsions

  2018cites this paper
• Broad-spectrum antiviral JL122 blocks infection and inhibits transmission of aquatic rhabdoviruses.

  2018cites this paper
• Insight Into the Molecular Dynamic Simulation Studies of Reactive Oxygen Species in Native Skin Membrane

  2018cites this paper
• Antioxidative activity of high-density lipoprotein (HDL): Mechanistic insights into potential clinical benefit

  2017cites this paper
• Direct 1O2 optical excitation: A tool for redox biology

  2017cites this paper
• Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes.

  2017cites this paper
• Cholesterol Hydroperoxide Generation, Translocation, and Reductive Turnover in Biological Systems

  2017cites this paper
• Monitoring Interfacial Lipid Oxidation in Oil-in-Water Emulsions Using Spatially Resolved Optical Techniques.

  2017cites this paper
• Estratégias para as opções dietéticas de combate à obesidade relacionadas com a morbilidade cardiometabolica

  2017cites this paper
• Cholesterol as a natural probe for free radical-mediated lipid peroxidation in biological membranes and lipoproteins.

  2016cites this paper
• Molecular simulations of the effects of phospholipid and cholesterol peroxidation on lipid membrane properties.

  2016cites this paper
• Intracellular singlet oxygen photosensitizers: on the road to solving the problems of sensitizer degradation, bleaching and relocalization.

  2016cites this paper
• Evaluation of oxygen dependence on in vitro and in vivo cytotoxicity of photoimmunotherapy using IR-700-antibody conjugates.

  2015cites this paper
• A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways

  2015cites this paper
• MECHANISTIC STUDIES ON THE PHOTOTOXICITY OF ROSUVASTATIN, ITRACONAZOLE AND IMATINIB

  2015cites this paper
• Photosensitisation studies of silicone polymer doped with methylene blue and nanogold for antimicrobial applications

  2015cites this paper
• Direct 765 nm Optical Excitation of Molecular Oxygen in Solution and in Single Mammalian Cells.

  2015cites this paper
• Scope and limitations of the TEMPO/EPR method for singlet oxygen detection: the misleading role of electron transfer.

  2014cites this paper
• Photodamage of lipid bilayers by irradiation of a fluorescently labeled cell-penetrating peptide.

  2014cites this paper
• Selenoprotein K form an intermolecular diselenide bond with unusually high redox potential

  2014cites this paper
• Macrophage mitochondrial damage from StAR transport of 7‐hydroperoxycholesterol: Implications for oxidative stress‐impaired reverse cholesterol transport

  2014cites this paper
• Regulation of the Unbalanced Redox State in a Schizosaccharomyces Pombe tert-Butyl Hydroperoxide-Resistant Mutant

  2014cites this paper
• Adaptation to tert‐butyl hydroperoxide at a plasma membrane level in the fission yeast Schizosaccharomyces pombe parental strain and its t‐BuOOH‐resistant mutant

  2014cites this paper
• UNIVERSIDADE DE SÃO PAULO INSTITUTO DE QUÍMICA Programa de Pós-Graduação em Ciências Biológicas (Bioquímica)

  2014influential citation
• Regulation of the unbalanced R edox state in a Sc HI z OSA cc HA r O myce S p O m B e tert-butyl hyd R ope R oxide- R esistant mutant

  2014cites this paper
• Singlet molecular oxygen generated by biological hydroperoxides.

  2014cites this paper
• Luminescence spectroscopy of singlet oxygen enables monitoring of oxygen consumption in biological systems consisting of fatty acids.

  2013cites this paper
• Deleterious Cholesterol Hydroperoxide Trafficking in Steroidogenic Acute Regulatory (StAR) Protein-expressing MA-10 Leydig Cells

  2013cites this paper
• Principles in Redox Signaling: From Chemistry to Functional Significance

  2013cites this paper
• Non-selective distribution of isomeric cholesterol hydroperoxides to microdomains in cell membranes and activation of matrix metalloproteinase activity in a model of dermal cells.

  2013cites this paper
• UVA irradiation of fatty acids and their oxidized products substantially increases their ability to generate singlet oxygen.

  2013cites this paper
• Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential.

  2013cites this paper
• Generation and Reactivity of Lipid Hydroperoxides in Biological Systems

  2013cites this paper
• A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

  2013cites this paper
• Secondary reactive oxygen species production after PDT during pulmonary tumor growth in sera of nude mice.

  2013cites this paper
• Transcriptomic insights into the molecular response of Saccharomyces cerevisiae to linoleic acid hydroperoxide

  2013cites this paper
• Influence of animal species on secondary oxidant activation in serum exposed to singlet oxygen.

  2012cites this paper
• In vitro and in vivo protection by melatonin against the decline of elongation factor‐2 caused by lipid peroxidation: preservation of protein synthesis

  2012cites this paper
• Increased singlet oxygen-induced secondary ROS production in the serum of cancer patients.

  2012cites this paper
• Mitochondria and reactive oxygen species. Which role in physiology and pathology?

  2012cites this paper
• Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species

  2012cites this paper
• The use of the light microscopy and the atomic force microscopy for studying cell death under hydrogen peroxide influence

  2012cites this paper
• Behavior of the thermal diffusivity of native and oxidized human low-density lipoprotein solutions studied by the Z-scan technique

  2012cites this paper
• Evidence for antioxidants consumption in the coronary blood of patients with an acute myocardial infarction

  2012cites this paper
• Serum resistance to singlet oxygen in patients with diabetes mellitus in comparison to healthy donors.

  2011cites this paper
• Permeabilization of the Mitochondrial Outer Membrane by Bax/Truncated Bid (tBid) Proteins as Sensitized by Cardiolipin Hydroperoxide Translocation

  2011cites this paper
• Functionality of HDL particles: Heterogeneity and relationships to cardiovascular disease

  2011cites this paper
• Development of a highly sensitive fluorescence probe for hydrogen peroxide.

  2011cites this paper
• Lipid hydroperoxide-induced and hemoglobin-enhanced oxidative damage to colon cancer cells.

  2011cites this paper
• DNA strand breaks and base modifications induced by cholesterol hydroperoxides

  2011cites this paper
• StarD4-mediated translocation of 7-hydroperoxycholesterol to isolated mitochondria: deleterious effects and implications for steroidogenesis under oxidative stress conditions.

  2010cites this paper
• Binding to and photo-oxidation of cardiolipin by the phthalocyanine photosensitizer Pc 4.

  2010cites this paper
• Antiatherogenic function of HDL particle subpopulations: focus on antioxidative activities

  2010cites this paper
• Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects

  2010cites this paper
• Comparative Study of the in Vitro Protective Effects of Several Antioxidants on Elongation Factor 2 under Oxidative Stress Conditions

  2010cites this paper
• Caracterização funcional de uma nova proteína antioxidante: Ohr (Organic Hydroperoxide Resistance Protein). Vias de redução e expressão em Xylella fastidiosa

  2010cites this paper
• HDL: More Than Just Cholesterol

  2010cites this paper
• Singlet molecular oxygen-quenching activity of carotenoids: relevance to protection of the skin from photoaging

  2010cites this paper
• Efecto de Cocoanox, un cacao rico en polifenoles, en ratas espontáneamente hipertensas

  2010cites this paper
• Surprising Inability of Singlet Oxygen‐generated 6‐Hydroperoxycholesterol to Induce Damaging Free Radical Lipid Peroxidation in Cell Membranes †

  2010cites this paper
• Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts.

  2010cites this paper
• HDL3-Mediated Inactivation of LDL-Associated Phospholipid Hydroperoxides Is Determined by the Redox Status of Apolipoprotein A-I and HDL Particle Surface Lipid Rigidity: Relevance to Inflammation and Atherogenesis

  2009cites this paper
• Signaling events in apoptotic photokilling of 5-aminolevulinic acid-treated tumor cells: inhibitory effects of nitric oxide.

  2009cites this paper
• Adduct formation of 4-hydroxynonenal and malondialdehyde with elongation factor-2 in vitro and in vivo.

  2009cites this paper
• PDT-induced in vitro bystander effect

  2009cites this paper
• Molecular modeling of the reactive configuration of peroxidized lipid and α-tocopherol in the membrane

  2009cites this paper
• Reactive Oxygen Species in the Induction of Toxicity

  2009cites this paper
• Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli.

  2009cites this paper
• Secondary oxidants in human serum exposed to singlet oxygen: the influence of hemolysis

  2009cites this paper
• Photodynamic Treatment of Culture Medium Containing Serum Induces Long-Lasting Toxicity In Vitro

  2009cites this paper
• Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling.

  2008cites this paper
• Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.

  2008cites this paper