Traumatic Brain Injury-Induced Ependymal Ciliary Loss Decreases Cerebral Spinal Fluid Flow

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Neurotrauma

• Publication date

  2014-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/neu.2013.3110PMID 24749541PMCID PMC4132584
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

  2013cited by this paper
• A Five Year Prospective Investigation of Anterior Pituitary Function after Traumatic Brain Injury: Is Hypopituitarism Long-Term after Head Trauma Associated with Autoimmunity?

  2013cited by this paper
• T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection.

  2012cited by this paper
• Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.

  2012cited by this paper
• Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model

  2012cited by this paper
• The Locus Ceruleus Responds to Signaling Molecules Obtained from the CSF by Transfer through Tanycytes

  2011cited by this paper
• Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

  2010cited by this paper
• Insight into the patterns of cerebrospinal fluid flow in the human ventricular system using MR velocity mapping

  2010cited by this paper
• Elevated Cerebrospinal Fluid Lactate Concentrations in Patients with Bipolar Disorder and Schizophrenia: Implications for the Mitochondrial Dysfunction Hypothesis

  2010cited by this paper
• Cilia dysfunction.

  2010cited by this paper
• Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

  2010cited by this paper
• Traumatic brain injury in the United States; emergency department visits, hospitalizations, and deaths, 2002-2006

  2010cited by this paper
• Dietary branched chain amino acids ameliorate injury-induced cognitive impairment

  2009cited by this paper
• Epithelium, cilia, and mucus: their importance in chronic rhinosinusitis.

  2009cited by this paper
• Motile Cilia of Human Airway Epithelia Are Chemosensory

  2009cited by this paper
• The Human Nervous System Structure and Function, 6th edn

  2009cited by this paper
• Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis.

  2009cited by this paper
• Mutations in Hydin impair ciliary motility in mice

  2008cited by this paper
• Protein accumulation in traumatic brain injury

  2007cited by this paper
• Effect of oestradiol and progesterone on the instant and directional velocity of microsphere movements in the rat oviduct: gap junctions mediate the kinetic effect of oestradiol.

  2007cited by this paper
• Brain injury impairs dentate gyrus inhibitory efficacy.

  2007cited by this paper
• Intracerebroventricular antisense knockdown of Gαi2 results in ciliary stasis and ventricular dilatation in the rat

  2007cited by this paper
• Accelerated mortality from hydrocephalus and pneumonia in mice with a combined deficiency of SPAG6 and SPAG16L reveals a functional interrelationship between the two central apparatus proteins.

  2007cited by this paper
• Primary ciliary dyskinesia: current state of the art

  2007cited by this paper
• Heat Shock Transcription Factor 1 Is Required for Maintenance of Ciliary Beating in Mice*

  2007cited by this paper
• Traumatic brain injury and Alzheimer's disease: a review.

  2007cited by this paper
• Murine nasal septa for respiratory epithelial air-liquid interface cultures.

  2007cited by this paper
• Mechanosensitivity of mouse tracheal ciliary beat frequency: roles for Ca2+, purinergic signaling, tonicity, and viscosity.

  2007cited by this paper
• Incidence of Traumatic Brain Injury in the United States, 2003

  2006cited by this paper
• The Human Nervous System: Structure and Function, 6th ed., C.R. Noback, N.L. Strominger, R.J. Demarest, D.A. Ruggiero (Eds.). The Humana Press (2005), Price $99.50, ISBN: 1-588-29-039-5

  2006influential reference
• Traumatic brain injury in the United States; emergency department visits, hospitalizations, and deaths

  2006cited by this paper
• The ciliopathies: an emerging class of human genetic disorders.

  2006cited by this paper
• Mechanisms underlying the inability to induce area CA1 LTP in the mouse after traumatic brain injury

  2006cited by this paper
• Regional hippocampal alteration associated with cognitive deficit following experimental brain injury: a systems, network and cellular evaluation.

  2005cited by this paper
• Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus

  2005cited by this paper
• TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

  2005cited by this paper
• Cilia‐related diseases

  2004cited by this paper
• Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF

  2004cited by this paper
• Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation.

  2004cited by this paper
• Regulation of human airway ciliary beat frequency by intracellular pH

  2004cited by this paper
• Absent inner dynein arms in a fetus with familial hydrocephalus‐situs abnormality

  2004cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Male Infertility, Impaired Sperm Motility, and Hydrocephalus in Mice Deficient in Sperm-Associated Antigen 6

  2002cited by this paper
• Primary ciliary dyskinesia with situs inversus totalis, hydrocephalus internus and cardiac malformations in a dog.

  2001cited by this paper
• Ciliary dyskinesia associated with hydrocephalus and mental retardation in a Jordanian family.

  2001cited by this paper
• Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype

  2001cited by this paper
• Post-traumatic hydrocephalus

  2000cited by this paper
• CSF signaling in physiology and behavior.

  2000cited by this paper
• High Melatonin Concentrations in Third Ventricular Cerebrospinal Fluid Are Not due to Galen Vein Blood Recirculating through the Choroid Plexus1.

  1999cited by this paper
• Sleep: A Physiologic Role for IL‐1β and TNF‐α a

  1998cited by this paper
• Relationship of senescence of cerebrospinal fluid circulatory system to dementias of the aged.

  1998cited by this paper
• The ependyma in chronic hydrocephalus

  1998cited by this paper
• Instantaneous Perturbation of Dentate Interneuronal Networks by a Pressure Wave-Transient Delivered to the Neocortex

  1997cited by this paper
• A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

  1996cited by this paper
• The Human Nervous System: Structure and Function

  1996influential reference
• Role of disturbance of ependymal ciliary movement in development of hydrocephalus in rats

  1993cited by this paper
• Interleukin 1-receptor antagonist blocks interleukin 1-induced sleep and fever.

  1991cited by this paper
• Interleukin 1 alters rat sleep: temporal and dose-related effects.

  1991cited by this paper
• Ciliary motility in brain ventricular system and trachea of hamsters.

  1985cited by this paper
• Ultrastructural basis of the coordination of ciliary movement. Contractile function of the interconnecting cross-striated roots in ependymal epithelium.

  1984cited by this paper
• Posttraumatic Hydrocephalus

  1984cited by this paper
• Ultrastructural Basis of the Coordination of Ciliary Movement

  1984cited by this paper
• Ventricular Ependyma of Normal and Hydrocephalic Subjects: a Scanning Electronmicroscopic Study

  1980cited by this paper
• [Post-traumatic hydrocephalus].

  1976cited by this paper

• Neuroglial Advances: New Roles for Established Players

  2025cites this paper
• Modulating Cerebrospinal Fluid Composition in Neurodegenerative Processes: Modern Drug Delivery and Clearance Strategies

  2025cites this paper
• Navigating anterior pituitary dysfunction after traumatic brain injury: mechanisms, diagnosis, and management.

  2025cites this paper
• GFAP Degradation in TBI: Linking Novel Modified Products to Astrocyte Pathology and Patient Outcome

  2025cites this paper
• Childhood-onset Hydrocephalus

  2025cites this paper
• Multiciliated ependymal cells: an update on biology and pathology in the adult brain

  2024cites this paper
• Advancing Hydrocephalus Management: Pathogenesis Insights, Therapeutic Innovations, and Emerging Challenges

  2024cites this paper
• Abnormalities of cortical and subcortical spontaneous brain activity unveil mechanisms of disorders of consciousness and prognosis in patients with severe traumatic brain injury

  2024cites this paper
• Cilia dysfunction in the lateral ventricles after neonatal intraventricular hemorrhage does not lead to functional changes in cilia-based CSF flow networks

  2024cites this paper
• Temporal and structural sensitivities of major biomarkers for detecting neuropathology after traumatic brain injury in the mouse

  2024cites this paper
• Incidence and risk factors of posttraumatic hydrocephalus and its association with outcome following intensive care unit treatment for traumatic brain injury: a multicenter observational study.

  2023cites this paper
• Measurement of changes in cerebrospinal fluid pulsation after traumatic brain injury using echo‐planar imaging‐based functional MRI

  2023cites this paper
• The pathological potential of ependymal cells in mild traumatic brain injury

  2023influential citation
• Single-cell transcriptomics reveals ependymal subtypes related to cytoskeleton dynamics as the core driver of syringomyelia pathological development

  2023cites this paper
• Detection and verification of neurodegeneration after traumatic brain injury in the mouse: Immunohistochemical staining for amyloid precursor protein

  2023influential citation
• Impairment of Connexin 43 may initiate cilia decline in syringomyelia.

  2023cites this paper
• Post-Traumatic Hypopituitarism: A Neglected Consequence of Traumatic Brain Injury

  2023cites this paper
• Ependymal Cilia: Physiology and Role in Hydrocephalus

  2022cites this paper
• Risk Factor of Posthemorrhagic Hydrocephalus: Cerebrospinal Fluid Total Protein

  2022cites this paper
• Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With Traumatic Brain Injury

  2022cites this paper
• Prediction of adult post-hemorrhagic hydrocephalus: a risk score based on clinical data

  2022cites this paper
• Fluids and flows in brain cancer and neurological disorders

  2022cites this paper
• Ependymal cells and neurodegenerative disease: outcomes of compromised ependymal barrier function

  2022cites this paper
• Choroid plexus epithelial cells as a model to study nongenomic steroid signaling and its effect on ion channel function.

  2021cites this paper
• Early onset senescence and cognitive impairment in a murine model of repeated mTBI

  2021cites this paper
• Diffusion Tensor Imaging Detects Acute and Subacute Changes in Corpus Callosum in Blast-Induced Traumatic Brain Injury

  2020cites this paper
• FATIGUE FOLLOWING BRAIN INJURY

  2020cites this paper
• Neurologic Complications After Traumatic Brain Injury

  2019cites this paper
• Incidence of hydrocephalus in traumatic brain injury

  2019influential citation
• Chronic Traumatic Encephalopathy

  2019cites this paper
• Extended Combined Neonatal Treatment With Erythropoietin Plus Melatonin Prevents Posthemorrhagic Hydrocephalus of Prematurity in Rats

  2018cites this paper
• Dietary therapy restores glutamatergic input to orexin/hypocretin neurons after traumatic brain injury in mice

  2018cites this paper
• Posttraumatic Hydrocephalus: Relevance, Mechanisms, Treatment, and Outcome

  2018cites this paper
• Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes.

  2017cites this paper
• Alzheimer’s Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus

  2017cites this paper
• Chronic Traumatic Encephalopathy: Known Causes, Unknown Effects.

  2017cites this paper
• Optimized Protocol of Methanol Treatment for Immunofluorescent Staining in Fixed Brain Slices

  2017cites this paper
• Post-hemorrhagic hydrocephalus: Recent advances and new therapeutic insights.

  2017cites this paper
• Role of Glia in Memory Deficits Following Traumatic Brain Injury: Biomarkers of Glia Dysfunction

  2016cites this paper
• Ventriculomegaly in Aging, Injury and Disease

  2016cites this paper
• Particle tracking in drug and gene delivery research: State-of-the-art applications and methods.

  2015cites this paper