The structural integrity exerted by N-terminal pyroglutamate is crucial for the cytotoxicity of frog ribonuclease from Rana pipiens.

Y. Liao,Sui-Chi Wang,Y. Leu,Chiu-Feng Wang,Shu-Ting Chang,Yu-Ting Hong,Yun-Ru Pan,Chinpan Chen

Published 2003 in Nucleic Acids Research

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