Covalent attachment of heme to the protein moiety in an insect E75 nitric oxide sensor.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biochemistry

• Publication date

  2012-09-18

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/bi300848xPMID 22946928PMCID PMC3448046
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Insect nuclear receptors.

  2012cited by this paper
• Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase.

  2011cited by this paper
• Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development.

  2011cited by this paper
• Origin and evolution of the ligand-binding ability of nuclear receptors.

  2011cited by this paper
• Nitric oxide coordinates metabolism, growth, and development via the nuclear receptor E75.

  2011influential reference
• Faculty Opinions recommendation of Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction.

  2011cited by this paper
• Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

  2010cited by this paper
• Thiol-disulfide Redox Dependence of Heme Binding and Heme Ligand Switching in Nuclear Hormone Receptor Rev-erbβ*

  2010cited by this paper
• Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase.

  2009cited by this paper
• Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO.

  2009influential reference
• The nuclear receptor E75A has a novel pair-rule-like function in patterning the milkweed bug, Oncopeltus fasciatus.

  2009influential reference
• The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

  2009influential reference
• The nuclear hormone receptor BgE75 links molting and developmental progression in the direct-developing insect Blattella germanica.

  2008influential reference
• Rev‐erbα gives a time cue to metabolism

  2008cited by this paper
• Rev-erb alpha gives a time cue to metabolism.

  2008cited by this paper
• Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways.

  2007cited by this paper
• Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ

  2007cited by this paper
• Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

  2007cited by this paper
• An Escherichia coli expression–based method for heme substitution

  2007cited by this paper
• Structural insight into the constitutive repression function of the nuclear receptor Rev-erbbeta.

  2007cited by this paper
• Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.

  2007influential reference
• Autocatalytic formation of a covalent link between tryptophan 41 and the heme in ascorbate peroxidase.

  2007cited by this paper
• Unexpected NO-dependent DNA binding by the CooA homolog from Carboxydothermus hydrogenoformans.

  2006cited by this paper
• Drosophila nuclear receptor E75 is a thiolate hemoprotein.

  2006influential reference
• The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?

  2006cited by this paper
• Nuclear receptors — a perspective from Drosophila

  2005cited by this paper
• The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene.

  2005cited by this paper
• The Drosophila nuclear receptor e75 contains heme and is gas responsive.

  2005influential reference
• Autocatalytic formation of green heme: evidence for H2O2-dependent formation of a covalent methionine-heme linkage in ascorbate peroxidase.

  2004cited by this paper
• Reactivity Studies of the Fe(III) and Fe(II)NO Forms of Human Neuroglobin Reveal a Potential Role against Oxidative Stress*

  2004cited by this paper
• Hormonal regulation and functional role of Drosophila E75A orphan nuclear receptor in the juvenile hormone signaling pathway.

  2004cited by this paper
• Characterization of the heme–histidine cross-link in cyanobacterial hemoglobins from Synechocystis sp. PCC 6803 and Synechococcus sp. PCC 7002

  2004cited by this paper
• Cyanide binding to hexacoordinate cyanobacterial hemoglobins: hydrogen-bonding network and heme pocket rearrangement in ferric H117A Synechocystis hemoglobin.

  2004cited by this paper
• Differential control of MHR3 promoter activity by isoforms of the ecdysone receptor and inhibitory effects of E75A and MHR3.

  2004cited by this paper
• The evolution of the nuclear receptor superfamily.

  2004cited by this paper
• Autocatalytic radical reactions in physiological prosthetic heme modification.

  2003cited by this paper
• Covalent heme binding to CYP4B1 via Glu310 and a carbocation porphyrin intermediate.

  2003cited by this paper
• The BmE75 Nuclear Receptors Function as Dominant Repressors of the Nuclear Receptor BmHR3A*

  2002cited by this paper
• Autocatalytic Mechanism and Consequences of Covalent Heme Attachment in the Cytochrome P4504A Family*

  2002cited by this paper
• Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.

  2002cited by this paper
• Nature of the displaceable heme-axial residue in the EcDos protein, a heme-based sensor from Escherichia coli.

  2002cited by this paper
• Asp-225 and Glu-375 in Autocatalytic Attachment of the Prosthetic Heme Group of Lactoperoxidase*

  2002cited by this paper
• Covalent linkage of prosthetic heme to CYP4 family P450 enzymes.

  2001cited by this paper
• X-ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution*

  2000cited by this paper
• Electronic absorption, EPR, and resonance raman spectroscopy of CooA, a CO-sensing transcription activator from R. rubrum, reveals a five-coordinate NO-heme.

  2000influential reference
• The Sulfonium Ion Linkage in Myeloperoxidase

  1999cited by this paper
• Mutation of the Five Conserved Histidines in the Endothelial Nitric-oxide Synthase Hemoprotein Domain

  1999cited by this paper
• Role of the distal phenylalanine 54 on the structure, stability, and ligand binding of Coprinus cinereus peroxidase.

  1999cited by this paper
• Coordination of Drosophila Metamorphosis by Two Ecdysone-Induced Nuclear Receptors

  1997cited by this paper
• Human endothelial nitric oxide synthase: expression in Escherichia coli, coexpression with calmodulin, and characterization.

  1996cited by this paper
• Trans effects in nitric oxide binding to myoglobin cavity mutant H93G.

  1996cited by this paper
• Reactions of nitric oxide and peroxynitrite with organic molecules and ferrihorseradish peroxidase: interference with the determination of hydrogen peroxide.

  1996cited by this paper
• Electron paramagnetic resonance spectral evidence for the formation of a pentacoordinate nitrosyl-heme complex on soluble guanylate cyclase.

  1995cited by this paper
• The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

  1995cited by this paper
• The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

  1990cited by this paper
• High-resolution three-dimensional structure of horse heart cytochrome c.

  1990cited by this paper
• Simultaneous determination of hemes a, b, and c from pyridine hemochrome spectra.

  1987cited by this paper

• Expression Analysis of Hormone Receptor 38 (HR38) and Ecdysone-Induced Protein 75 (E75) Genes and Their Functional Implications in the Development of Heortia vitessoides Moore

  2025cites this paper
• Uncovering the diversity of invertebrate nuclear receptors ligands.

  2025cites this paper
• Low concentrations of cyantraniliprole negatively affects the development of Spodoptera frugiperda by disruption of ecdysteroid biosynthesis and carbohydrate and lipid metabolism.

  2024cites this paper
• Characterization of Heme Binding to PEFR, A Marr Transcriptional Regulator

  2022cites this paper
• Combined vibrational spectroscopy and electrochemistry for studying biological and materials systems

  2020cites this paper
• Heme: emergent roles of heme in signal transduction, functional regulation and as catalytic centres.

  2019cites this paper
• Ironing out the Details: Exploring the Role of Iron and Heme in Blood-Sucking Arthropods

  2018influential citation
• Distinct mechanisms for DNA cleavage by myoglobin with a designed heme active center.

  2016cites this paper
• Nuclear receptor ecdysone‐induced protein 75 is required for larval–pupal metamorphosis in the Colorado potato beetle Leptinotarsa decemlineata (Say)

  2016cites this paper
• 20-Hydroxyecdysone (20E) Primary Response Gene E75 Isoforms Mediate Steroidogenesis Autoregulation and Regulate Developmental Timing in Bombyx*

  2016cites this paper
• Interacciones de proteína-péptido: estudio de DYLLT1 y del dominio PDZ de la Óxido Nítrico Sintasa neuronal

  2016influential citation
• Triple helical collagen-like peptide interactions with selected polyphenolic compounds

  2015cites this paper
• Transcriptional Regulation via Nuclear Receptor Crosstalk Required for the Drosophila Circadian Clock

  2015cites this paper
• The broad diversity of heme-protein cross-links: An overview.

  2015cites this paper
• Bombyx E75 isoforms display stage- and tissue-specific responses to 20-hydroxyecdysone

  2015cites this paper
• Gaseous O2, NO, and CO in signal transduction: structure and function relationships of heme-based gas sensors and heme-redox sensors.

  2015cites this paper
• Significantly Enhanced Heme Retention Ability of Myoglobin Engineered to Mimic the Third Covalent Linkage by Nonaxial Histidine to Heme (Vinyl) in Synechocystis Hemoglobin*

  2014cites this paper
• Genetic link between heme oxygenase and the signaling pathway of DNA damage in Drosophila melanogaster.

  2013cites this paper
• Spatial Profiling of Nuclear Receptor Transcription Patterns over the Course of Drosophila Development

  2013cites this paper
• Heme Sensor Proteins*

  2013cites this paper