Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Pharmacy and Science

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1002/JPS.20209PMID 15761930
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Peptide and Protein Drug Delivery

  2024cited by this paper
• Controlled Release of Polypeptides and Other Macromolecules

  2004cited by this paper
• Spray freezing into liquid nitrogen for highly stable protein nanostructured microparticles.

  2004cited by this paper
• Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres.

  2003cited by this paper
• PLG Microsphere Size Controls Drug Release Rate Through Several Competing Factors

  2003cited by this paper
• A potential approach for decreasing the burst effect of protein from PLGA microspheres.

  2003cited by this paper
• Preparation and in Vitro/in Vivo Evaluation of Insulin-Loaded Poly(Acryloyl-Hydroxyethyl Starch)-PLGA Composite Microspheres

  2003cited by this paper
• Cisplatin incorporated in microspheres: development and fundamental studies for its clinical application.

  2003cited by this paper
• Poly(d,l-Lactide-Co-Glycolide) Encapsulated Poly(Vinyl Alcohol) Hydrogel as a Drug Delivery System

  2002cited by this paper
• Preparation and characterization of microparticles containing peptide produced by a novel process: spray freezing into liquid.

  2002cited by this paper
• Protein spray freeze drying. 2. Effect of formulation variables on particle size and stability.

  2002cited by this paper
• Insulin-loaded biodegradable PLGA microcapsules: initial burst release controlled by hydrophilic additives.

  2002cited by this paper
• Recent trends in stabilizing protein structure upon encapsulation and release from bioerodible polymers

  2002cited by this paper
• Double-walled microspheres for the sustained release of a highly water soluble drug: characterization and irradiation studies.

  2002cited by this paper
• Characterization of the initial burst release of a model peptide from poly(D,L-lactide-co-glycolide) microspheres.

  2002cited by this paper
• Stabilization and Controlled Release of Bovine Serum Albumin Encapsulated in Poly(D, L-lactide) and Poly(ethylene glycol) Microsphere Blends

  2001cited by this paper
• Stabilization of a model formalinized protein antigen encapsulated in poly(lactide-co-glycolide)-based microspheres.

  2001cited by this paper
• Reduction of structural perturbations in bovine serum albumin by non‐aqueous microencapsulation

  2001cited by this paper
• Emerging protein delivery methods.

  2001cited by this paper
• Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method.

  2001cited by this paper
• Prevention of structural perturbations and aggregation upon encapsulation of bovine serum albumin into poly(lactide‐co‐glycolide) microspheres using the solid‐in‐oil‐in‐water technique

  2001cited by this paper
• Protein Spray-Freeze Drying. Effect of Atomization Conditions on Particle Size and Stability

  2000cited by this paper
• Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes.

  2000cited by this paper
• Recent Progress in Biomolecular Engineering

  2000cited by this paper
• The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices.

  2000cited by this paper
• Particle size and loading efficiency of poly(D,L-lactic-co-glycolic acid) multiphase microspheres containing water soluble substances prepared by the hydrous and anhydrous solvent evaporation methods.

  1999cited by this paper
• Formulation strategies for the stabilization of tetanus toxoid in poly(lactide-co-glycolide) microspheres.

  1999cited by this paper
• FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres.

  1999cited by this paper
• Structure‐guided Encapsulation of Bovine Serum Albumin in Poly(DL‐lactic‐co‐glycolic) Acid

  1998cited by this paper
• New strategies for the microencapsulation of tetanus vaccine.

  1998cited by this paper
• On Protein Denaturation in Aqueous−Organic Mixtures but Not in Pure Organic Solvents

  1996cited by this paper
• Lyophilization-induced reversible changes in the secondary structure of proteins.

  1995cited by this paper
• All About Albumin: Biochemistry, Genetics, and Medical Applications

  1995cited by this paper
• Microencapsulation using poly (L-lactic acid) II: Preparative variables affecting microcapsule properties.

  1990cited by this paper
• Transport rates of proteins in porous materials with known microgeometry.

  1989cited by this paper
• Polymers for sustained macromolecule release: procedures to fabricate reproducible delivery systems and control release kinetics.

  1980cited by this paper

• Fighting cancer smarter: Using hydrogel delivery systems to target chemokines.

  2025cites this paper
• Genetically Encoded Self-Assembling Protein Nanoparticles for the Targeted Delivery In Vitro and In Vivo

  2023cites this paper
• Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery

  2022cites this paper
• Evaluation of various techniques for production of inhalable dry powders for pulmonary delivery of peptide and protein

  2022cites this paper
• Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo

  2022cites this paper
• Computational modeling of dry-powder inhalers for pulmonary drug delivery

  2020cites this paper
• Trends in Nanotechnology for Practical Applications

  2019cites this paper
• Development of Inhalable Dry Gene Powders for Pulmonary Drug Delivery by Spray-Freeze-Drying

  2019cites this paper
• Microspheres as intraocular therapeutic tools in chronic diseases of the optic nerve and retina

  2018cites this paper
• Characterisation of Nanoestructured Potato Starch Powders with Blackberry (Rubus fruticosus Var. Brazos) Juice

  2018cites this paper
• Extended-release formulations of somatostatin for ocular application and their effect on vascular endothelial growth factor as a biomarker of diabetic retinopathy

  2018cites this paper
• Polymerization-induced self-assembly of large-scale iohexol nanoparticles as contrast agents for X-ray computed tomography imaging

  2018cites this paper
• X-ray visible and doxorubicin-loaded beads based on inherently radiopaque poly(lactic acid)-polyurethane for chemoembolization therapy.

  2017cites this paper
• Développement de formulations polymériques de S-nitrosoglutathion comme traitement per os pour prévenir les maladies inflammatoires chroniques de l’intestin

  2017cites this paper
• Nanoparticulate Drug Delivery Systems

  2016cites this paper
• Eco-friendly polymer-based nanocomposites for pharmaceutical applications

  2015cites this paper
• Pharmaceutical spray freeze drying.

  2015cites this paper
• Spray-freeze-drying: A novel process for the drying of foods and bioproducts

  2015cites this paper
• A method of lyophilizing vaccines containing aluminum salts into a dry powder without causing particle aggregation or decreasing the immunogenicity following reconstitution.

  2015cites this paper
• Development of injectable pH-degradable polymeric particles containing thrombin for minimally invasive delivery of fibrin glue to the heart post-myocardial infraction

  2014influential citation
• Examining the formulation of emulsion electrospinning for improving the release of bioactive proteins from electrospun fibers.

  2014cites this paper
• Effect of MgO nanofillers on burst release reduction from hydrogel nanocomposites

  2013cites this paper
• Glycosylation improves α-chymotrypsin stability upon encapsulation in poly(lactic-co-glycolic)acid microspheres

  2012cites this paper
• Novel biodegradable and pH-sensitive poly(ester amide) microspheres for oral insulin delivery.

  2012cites this paper
• Improved Enzyme Activity and Stability in Polymer Microspheres by Encapsulation of Protein Nanospheres

  2012cites this paper
• Release of FITC-BSA from poly(l-lactic acid) microspheres analysis using flow cytometry.

  2012cites this paper
• Microencapsulation of Dye‐ and Drug‐Loaded Particles for Imaging and Controlled Release of Multiple Drugs

  2012cites this paper
• Retinal ganglion cells survival in a glaucoma model by GDNF/Vit E PLGA microspheres prepared according to a novel microencapsulation procedure.

  2011cites this paper
• Biodegradable methoxy poly (ethylene glycol)-poly (lactide) nanoparticles for controlled delivery of dacarbazine: Preparation, characterization and anticancer activity evaluation

  2011cites this paper
• Controlled freezing and freeze drying: a versatile route for porous and micro‐/nano‐structured materials

  2011cites this paper
• REINFORCEMENT OF CHITOSAN NANOPARTICLES OBTAINED BY AN IONIC CROSS-LINKING PROCESS

  2011cites this paper
• Issues in long-term protein delivery using biodegradable microparticles.

  2010cites this paper
• Preparation of protein-loaded sustained-release microspheres via 'solid-in-oil-in-hydrophilic oil-in-ethanol (S/O/hO/E)' emulsification.

  2010cites this paper
• Composite microparticles with in vivo reduction of the burst release effect.

  2009cites this paper
• Controlled release of angiogenic growth factors from poly(lactic -co -glycolic acid) implants for therapeutic angiogenesis

  2009cites this paper
• Current approaches to stabilising and analysing proteins during microencapsulation in PLGA

  2009cites this paper
• Insulin nanoparticle preparation and encapsulation into poly(lactic-co-glycolic acid) microspheres by using an anhydrous system.

  2009cites this paper
• Current approaches to stabilising and analysing proteins during microencapsulation in PLGA.

  2009cites this paper
• Formation of Stable Submicron Protein Particles by Thin Film Freezing

  2008cites this paper
• Formation of spherical protein nanoparticles without impacting protein integrity

  2008cites this paper
• Modelowanie procesów wytwarzania proszków przy użyciu płynów w stanie nadkrytycznym

  2008cites this paper
• Grafting BSA onto poly[(L-lactide)-co-carbonate] microspheres by click chemistry.

  2008cites this paper
• Ethylenediamino Bridged Bis(β-cyclodextrin)/ Poly(DL-lactic-co-glycolic acid) Nanoparticles Prepared by Modified Double Emulsion Method : Effect of Polyvinyl Alcohol on Nanoparticle Properties

  2008cites this paper
• Bioinspired nanoencapsulation of purple membranes.

  2008cites this paper
• Analysis of initial burst in PLGA microparticles.

  2008cites this paper
• Analysis of initial burst in PLGA microparticles

  2008cites this paper
• DETERMINATION OF TRANS FATTY ACIDS BY MID INFRARED FOURIER TRANSFORM SPECTROSCOPY WITH OR WITHOUT NANOMATERIALS by MAYELI PERALTA CONTRERAS

  2007cites this paper
• Determination of trans fatty acids by mid infrared fourier transform spectroscopy with or without nanomaterials

  2007cites this paper
• Stable high surface area lactate dehydrogenase particles produced by spray freezing into liquid nitrogen.

  2007cites this paper
• PHARMACEUTICAL NANOTECHNOLOGY Polymer-Surfactant Nanoparticles for Sustained Release of Water-Soluble Drugs

  2007cites this paper
• Particle Engineering for Pulmonary Drug Delivery

  2007cites this paper
• Polymer-surfactant nanoparticles for sustained release of water-soluble drugs.

  2007cites this paper
• Pharmaceutical Applications of Nanoparticulate Drug-Delivery Systems

  2007cites this paper
• Effect of the microencapsulation of nanoparticles on the reduction of burst release.

  2007cites this paper
• Morphology of protein particles produced by spray freezing of concentrated solutions.

  2007cites this paper
• Engineering Pharmaceutical Nanoparticles

  2006cites this paper
• Cryogenic liquids, nanoparticles, and microencapsulation.

  2006cites this paper
• Spray freezing into liquid versus spray-freeze drying: influence of atomization on protein aggregation and biological activity.

  2006cites this paper
• Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film

  2005influential citation