In vivo insulin responsiveness for glucose uptake and production at eu- and hyperglycemic levels in normal and diabetic rats.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Biochimica et Biophysica Acta

• Publication date

  1992-01-23

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0304-4165(92)90059-4PMID 1739737
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats.

  1990cited by this paper
• Regulation of glucose transporters in diabetes.

  1990cited by this paper
• Effects of non-esterified fatty acid availability on insulin stimulated glucose utilisation and tissue pyruvate dehydrogenase activity in the rat

  1990cited by this paper
• Pretranslational suppression of an insulin-responsive glucose transporter in rats with diabetes mellitus.

  1989cited by this paper
• Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting

  1989cited by this paper
• Postreceptor defect in insulin action in streptozotocin-induced diabetic rats.

  1989cited by this paper
• Normal insulin sensitivity during the phase of glucose intolerance but insulin resistance at the onset of diabetes in the spontaneously diabetic BB rat

  1989cited by this paper
• Early appearance of in vivo insulin resistance in adult streptozotocin-injected rats.

  1989cited by this paper
• Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations.

  1989cited by this paper
• Regulation of glucose transporter messenger RNA in insulin-deficient states

  1989cited by this paper
• Effects of free fatty acids and ketone bodies on in vivo non-insulin-mediated glucose utilization and production in humans.

  1989cited by this paper
• Glucose Transport Is Rate Limiting for Skeletal Muscle Glucose Metabolism in Normal and STZ-Induced Diabetic Rats

  1988cited by this paper
• Insulin action is normalized in newly diagnosed type I diabetic patients after three months of insulin treatment.

  1988cited by this paper
• Improper expression of insulin receptors on fibroblasts from a leprechaun patient.

  1988cited by this paper
• Reduction of Insulin Clearance During Hyperglycemic Clamp: Dose-Response Study in Normal Humans

  1988cited by this paper
• Glucose-induced insulin resistance of skeletal-muscle glucose transport and uptake.

  1988cited by this paper
• Mechanisms limiting glycogen storage in muscle during prolonged insulin stimulation.

  1988cited by this paper
• Characterization by microdialysis of intracellular glucose level in subcutaneous tissue in humans.

  1988cited by this paper
• In Vitro Autoregulation of Glucose Utilization in Rat Soleus Muscle

  1987cited by this paper
• Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats.

  1987cited by this paper
• In vivo glucose metabolism in the awake rat: tracer and insulin clamp studies.

  1987cited by this paper
• Hyperglycemia Decreases Glucose Uptake in Type I Diabetes

  1987cited by this paper
• Reversibility of decreased insulin-stimulated glucose transport capacity in diabetic muscle with in vitro incubation. Insulin is not required.

  1987cited by this paper
• Heterogeneity of insulin action in muscle: influence of blood flow.

  1986cited by this paper
• Hepatic and peripheral insulin resistance following streptozotocin-induced insulin deficiency in the dog.

  1985cited by this paper
• Assessment of insulin sensitivity in vivo.

  1985cited by this paper
• In Vivo Hepatic and Peripheral Insulin Sensitivity in Rats with Non-insulin-dependent Diabetes Induced by Streptozocin: Assessment with the Insulin-Glucose Clamp Technique

  1985cited by this paper
• Glucose transport and metabolism in adipocytes from newly diagnosed untreated insulin-dependent diabetics. Severely impaired basal and postinsulin binding activities.

  1985cited by this paper
• Dose-response curves for in vivo insulin sensitivity in individual tissues in rats.

  1985cited by this paper
• Glucose as a regulator of insulin-sensitive hexose uptake in 3T3 adipocytes.

  1985cited by this paper
• Comparison of portal and peripheral insulin delivery on carbohydrate metabolism in streptozotocin-diabetic rats

  1985cited by this paper
• Insulin sensitivity in newly diagnosed type 1 diabetics after ketoacidosis and after three months of insulin therapy.

  1984cited by this paper
• Use of Glucose Uptake and Glucose Clearance for the Evaluation of Insulin Action In Vivo

  1984cited by this paper
• Impaired insulin action in newly diagnosed type 1 (insulin-dependent) diabetes mellitus

  1984cited by this paper
• Hepatic and peripheral insulin resistance: A common feature of Type 2 (non-insulin-dependent) and Type 1 (insulin-dependent) diabetes mellitus

  1982cited by this paper
• A new swivel for double infusion of fluids into rats.

  1981cited by this paper
• Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle.

  1979cited by this paper
• Glucose clamp technique: a method for quantifying insulin secretion and resistance.

  1979cited by this paper
• Reduced glucose transport and increased binding of insulin in adipocytes from diabetic and fasted rats.

  1978cited by this paper
• Streptozotocin: Its excretion and metabolism in the rat

  1976cited by this paper
• Distribution of 14C and 3H-streptozotocin in dogs and toadfish.

  1974cited by this paper
• A method for frequent sampling of blood and continuous infusion of fluids in the rat without disturbing the animal

  1969cited by this paper

• Magnesium stable isotope composition, but not concentration, responds to obesity and early insulin-resistant conditions in minipig

  2022cites this paper
• Beneficial effects of a plant-fish oil, slow carbohydrate diet on cardio-metabolic health exceed the correcting effects of metformin-pioglitazone in diabetic pigs fed a fast-food diet

  2021cites this paper
• Use of the hyperinsulinemic euglycemic clamp to assess insulin sensitivity in guinea pigs: dose response, partitioned glucose metabolism, and species comparisons.

  2017influential citation
• Medium‐chain fatty acids ameliorate insulin resistance caused by high‐fat diets in rats

  2009cites this paper
• Pharmacokinetic and Pharmacodynamic Aspects

  2009cites this paper
• Pancreatic Insulin Secretion in Rats Fed a Soy Protein High Fat Diet Depends on the Interaction between the Amino Acid Pattern and Isoflavones*

  2007cites this paper
• Association of insulin resistance with hyperglycemia in streptozotocin-diabetic pigs: effects of metformin at isoenergetic feeding in a type 2-like diabetic pig model.

  2006cites this paper
• An Increase in Peroxisomal Fatty Acid Oxidation Is Not Sufficient to Prevent Tissue Lipid Accumulation in hHTg Rats

  2002cites this paper
• Comparison of the Extrapancreatic Action of BRX‐220 and Pioglitazone in the High‐Fat Diet‐Induced Insulin Resistance

  2002cites this paper
• Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1

  2001cites this paper
• Effect of venous drainage site on insulin action after pancreas transplantation in the rat--is there insulin resistance and a risk for atherosclerosis?

  2000cites this paper
• Chronic physiologic hyperinsulinemia impairs suppression of plasma free fatty acids and increases de novo lipogenesis but does not cause dyslipidemia in conscious normal rats.

  1999cites this paper
• Time course of insulin action on tissue-specific intracellular glucose metabolism in normal rats.

  1998cites this paper
• The effect of the new oral hypoglycemic agent A-4166 on glucose turnover in the high fat diet-induced and/or in the hereditary insulin resistance of rats.

  1998cites this paper
• Neonatal de-afferentation of capsaicin-sensitive sensory nerves increases in vivo insulin sensitivity in conscious adult rats

  1998cites this paper
• Effect of hyperinsulinemia on plasma leptin concentrations and food intake in rats.

  1998cites this paper
• Seven Days of Euglycemic Hyperinsulinemia Induces Insulin Resistance for Glucose Metabolism but Not Hypertension, Elevated Catecholamine Levels, or Increased Sodium Retention in Conscious Normal Rats

  1997cites this paper
• Phenotype and Genotype Comparison of Hereditary Hypertriglyceridemic (hHTG) and Brown‐Norway (BN) Rats Identification of Quantitative Trait Loci (QTLs) for the Insulin Resistance Syndrome a

  1997cites this paper
• In vivo insulin action and resistance. The hyperinsulinaemic, euglycaemic clamp technique in conscious rats

  1996cites this paper
• Regulation of gene expression for lipogenic enzymes in the liver and adipose tissue of hereditary hypertriglyceridemic, insulin-resistant rats: effect of dietary sucrose and marine fish oil.

  1996cites this paper
• Pulsatile intravenous insulin replacement in streptozotocin-diabetic rats is more efficient than continuous delivery: effects on glycaemic control, insulin-mediated glucose metabolism and lipolysis

  1996cites this paper
• Excessive glucose production, rather than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats

  1995cites this paper
• Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats.

  1995cites this paper
• Use of a rat model for the simultaneous assessment of pharmacokinetic and pharmacodynamic aspects of bisphosphonate treatment: application to the study of intravenous 14C-labeled 1-hydroxy-3-(1-pyrrolidinyl)-propylidene-1,1-bisphosphonate.

  1994cites this paper