Myrrh exerts barrier-stabilising and -protective effects in HT-29/B6 and Caco-2 intestinal epithelial cells

No abstract is available for this paper.

• Publication year

  2017

• Venue

  International Journal of Colorectal Disease

• Publication date

  2017-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00384-016-2736-xPMID 27981377
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The ginger component 6-shogaol prevents TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling.

  2016cited by this paper
• Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation

  2015cited by this paper
• Distinct Kinetics in the Frequency of Peripheral CD4+ T Cells in Patients with Ulcerative Colitis Experiencing a Flare during Treatment with Mesalazine or with a Herbal Preparation of Myrrh, Chamomile, and Coffee Charcoal

  2014cited by this paper
• Efficacy and safety of a herbal medicinal product containing myrrh, chamomile and coffee charcoal for the treatment of gastrointestinal disorders: a non-interventional study

  2014cited by this paper
• Randomised clinical trial: a herbal preparation of myrrh, chamomile and coffee charcoal compared with mesalazine in maintaining remission in ulcerative colitis – a double‐blind, double‐dummy study

  2013cited by this paper
• STAT6 Deficiency Ameliorates Severity of Oxazolone Colitis by Decreasing Expression of Claudin-2 and Th2-Inducing Cytokines

  2013cited by this paper
• Comparative tight junction protein expressions in colonic Crohn’s disease, ulcerative colitis, and tuberculosis: a new perspective

  2012influential reference
• Apical acidity decreases inhibitory effect of omeprazole on Mg2+ absorption and claudin-7 and -12 expression in Caco-2 monolayers

  2012cited by this paper
• Claudins and other tight junction proteins.

  2012cited by this paper
• The genus Commiphora: a review of its traditional uses, phytochemistry and pharmacology.

  2012cited by this paper
• Claudin-2 Expression Increases Tumorigenicity of Colon Cancer Cells: Role of Epidermal Growth Factor Receptor Activation

  2011cited by this paper
• Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium*

  2011cited by this paper
• Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease

  2011cited by this paper
• Elucidating the principles of the molecular organization of heteropolymeric tight junction strands

  2011cited by this paper
• Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells.

  2010cited by this paper
• Claudin-2, a component of the tight junction, forms a paracellular water channel

  2010cited by this paper
• TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

  2010cited by this paper
• Claudin-3 acts as a sealing component of the tight junction for ions of either charge and uncharged solutes.

  2010cited by this paper
• The plant sterol guggulsterone attenuates inflammation and immune dysfunction in murine models of inflammatory bowel disease.

  2009cited by this paper
• TNFα up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling

  2009cited by this paper
• Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function

  2009cited by this paper
• Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells.

  2009cited by this paper
• Myrrh and trematodoses in Egypt: an overview of safety, efficacy and effectiveness profiles.

  2009cited by this paper
• STAT6 activation in ulcerative colitis: A new target for prevention of IL‐13‐induced colon epithelial cell dysfunction

  2009cited by this paper
• Intestinal mucosal barrier function in health and disease

  2009cited by this paper
• Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients

  2008cited by this paper
• Changes in the expression of claudins in active ulcerative colitis

  2008cited by this paper
• Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells.

  2008cited by this paper
• Therapeutic effects of guggul and its constituent guggulsterone: cardiovascular benefits.

  2007cited by this paper
• Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns.

  2006cited by this paper
• Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-alpha, IL-1beta and IL-2.

  2006cited by this paper
• Plant sterol guggulsterone inhibits nuclear factor‐&kgr;B signaling in intestinal epithelial cells by blocking I&kgr;B kinase and ameliorates acute murine colitis

  2006cited by this paper
• Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-α, IL-1β and IL-2

  2006cited by this paper
• Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

  2006cited by this paper
• Claudins upregulation in human colorectal cancer

  2005cited by this paper
• Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

  2005cited by this paper
• Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.

  2005cited by this paper
• Differential expression of claudin‐2 along the human intestine: Implication of GATA‐4 in the maintenance of claudin‐2 in differentiating cells

  2005cited by this paper
• Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

  2005cited by this paper
• Functional crosstalk between Wnt signaling and Cdx-related transcriptional activation in the regulation of the claudin-2 promoter activity.

  2004cited by this paper
• Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

  2002cited by this paper
• Conversion of Zonulae Occludentes from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells

  2001cited by this paper
• Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells.

  2000cited by this paper
• Epithelial Barrier and Transport Function of the Colon in Ulcerative Colitis

  2000cited by this paper
• Epithelial Barrier Defects in HT‐29/B6 Colonic Cell Monolayers Induced by Tumor Necrosis Factor‐α

  2000cited by this paper
• Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6.

  1999cited by this paper
• Junctional Adhesion Molecule, a Novel Member of the Immunoglobulin Superfamily That Distributes at Intercellular Junctions and Modulates Monocyte Transmigration

  1998cited by this paper
• Occludin: a novel integral membrane protein localizing at tight junctions

  1993cited by this paper
• Monographs on fragrance raw materials.

  1992cited by this paper
• Cl- secretion in epithelial monolayers of mucus-forming human colon cells (HT-29/B6).

  1991cited by this paper
• Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability.

  1989cited by this paper
• Monographs on fragrance raw materials.

  1983cited by this paper

• The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells

  2025cites this paper
• Darmfreundschaften pflegen

  2024cites this paper
• Myrrh protects against IL-13-induced epithelial barrier breakdown in HT-29/B6 cells

  2023cites this paper
• Xue-Jie-San restricts ferroptosis in Crohn’s disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop

  2023cites this paper
• The anti-inflammatory effect of myrrh ethanolic extract in comparison with prednisolone on an autoimmune disease rat model induced by silicate

  2022cites this paper
• Myrrh and Chamomile Flower Extract Inhibit Mediator Release from IgE-stimulated Mast-Cell-Like RBL-2H3 Cells

  2022cites this paper
• PI3Kγ is a novel regulator of TNFα signaling in the human colon cell line HT29/B6

  2022cites this paper
• Resveratrol Prevents Campylobacter jejuni-Induced Leaky gut by Restoring Occludin and Claudin-5 in the Paracellular Leak Pathway

  2021cites this paper
• Matrix Metalloproteinase-9 (MMP-9) induced disruption of intestinal epithelial tight junction barrier is mediated by NF-κB activation

  2021cites this paper
• Myrrhe – Arzneipflanze des Jahres 2021 hilft bei Magen-Darm-Störungen

  2021cites this paper
• Fallbeispiel: Die Darmbarriere stabilisieren

  2021cites this paper
• Sesquiterpenes from Myrrh and Their ICAM-1 Inhibitory Activity In Vitro

  2020cites this paper
• Distinct patterns of short-chain fatty acids during flare in patients with ulcerative colitis under treatment with mesalamine or a herbal combination of myrrh, chamomile flowers, and coffee charcoal: secondary analysis of a randomized controlled trial

  2020cites this paper
• Silica Animal Model for Autoimmune Disease and The Potential Use of Myrrh Compared with The Conventional Treatment

  2020influential citation
• IL-21 mediates microRNA-423-5p /claudin-5 signal pathway and intestinal barrier function in inflammatory bowel disease

  2020cites this paper
• Anti-Inflammatory and Barrier-Stabilising Effects of Myrrh, Coffee Charcoal and Chamomile Flower Extract in a Co-Culture Cell Model of the Intestinal Mucosa

  2020cites this paper
• Contribution of Epithelial Apoptosis and Subepithelial Immune Responses in Campylobacter jejuni-Induced Barrier Disruption

  2020cites this paper
• Curcumin Mitigates Immune-Induced Epithelial Barrier Dysfunction by Campylobacter jejuni

  2019cites this paper
• Catechin and Procyanidin B2 Modulate the Expression of Tight Junction Proteins but Do Not Protect from Inflammation-Induced Changes in Permeability in Human Intestinal Cell Monolayers

  2019cites this paper
• Freeze fracture: new avenues for the ultrastructural analysis of cells in vitro

  2017cites this paper