Excluded volume effects in gene stretching.

We investigate the effects excluded volume on the stretching of a single DNA in solution. We find that for small force F, the extension h is not linear in F but proportion to F(gamma), with gamma = (1 - nu)/nu, where nu is the well-known universal correlation length exponent. A freely joint chain model with the segment length chosen to reproduce the small extension behavior gives excellent fit to the experimental data of lambda-phage DNA over the whole experimental range. We show that excluded volume effects are stronger in two dimensions and derive results in two dimensions that are different from the three-dimensional results. This suggests experiments to be performed in these lower dimensions.

• Publication year

  2002

• Venue

  Biopolymers

• Publication date

  2002-06-17

• Fields of study

  Biology, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1002/BIP.10122arXiv cond-mat/0206327PMID 11979515
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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