Protective effect of quercetin on lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammatory cell influx

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Experimental biology and medicine

• Publication date

  2014-06-09

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1177/1535370214537743PMID 24912504
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011cited by this paper
• The Systemic Pro-Inflammatory Response in Sepsis

  2010cited by this paper
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• Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function.

  2009cited by this paper
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  2009cited by this paper
• Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat.

  2009cited by this paper
• Acute lung injury review.

  2009cited by this paper
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  2009cited by this paper
• Animal models of acute lung injury

  2008influential reference
• Health effects of quercetin: from antioxidant to nutraceutical.

  2008cited by this paper
• Role of Oxidants in Lung Injury During Sepsis

  2007influential reference
• Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.

  2007cited by this paper
• HMGB1 modulates inflammatory responses in LPS-activated macrophages

  2007cited by this paper
• Naturally occurring NF-kappaB inhibitors.

  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Pathophysiology of acute lung injury and the acute respiratory distress syndrome.

  2006cited by this paper
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  2005influential reference
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  2004influential reference
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  2004influential reference
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• Cytokine-mediated inflammation in acute lung injury.

  2003influential reference
• HMGB1 as a cytokine and therapeutic target

  2002cited by this paper
• Lipopolysaccharide endotoxins.

  2002cited by this paper
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