Chemical Reactivity as a Tool To Study Carcinogenicity: Reaction between Estradiol and Estrone 3, 4-Quinones Ultimate Carcinogens and Guanine

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Chemical Information and Modeling

• Publication date

  2004-02-18

• Fields of study

  Medicine, Chemistry, Computer Science

• Identifiers
  DOI 10.1021/ci030424nPMID 15032505
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer.

  2003cited by this paper
• Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial.

  2003cited by this paper
• Methoxyestrogens Exert Feedback Inhibition on Cytochrome P 450 1 A 1 and 1 B 11

  2003cited by this paper
• Human cytochrome P450 3A7 has a distinct high catalytic activity for the 16alpha-hydroxylation of estrone but not 17beta-estradiol.

  2003cited by this paper
• Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo.

  2003cited by this paper
• Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA.

  2003cited by this paper
• Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1.

  2003cited by this paper
• Spectral characterization of catechol estrogen quinone (CEQ)-derived DNA adducts and their identification in human breast tissue extract.

  2003cited by this paper
• Breast cancer and hormone-replacement therapy in the Million Women Study.

  2003cited by this paper
• Influence of Estrogen Plus Progestin on Breast Cancer and Mammography in Healthy Postmenopausal Women: The Women's Health Initiative Randomized Trial

  2003cited by this paper
• Carcinogenic activity in estrone and its derivatives: a theoretical study

  2003cited by this paper
• WEIGHING RISKS OF ESTROGEN THERAPY

  2003cited by this paper
• Human Cytochrome P450 3A7 Has a Distinct High Catalytic Activity for the 16 -Hydroxylation of Estrone but not 17 -Estradiol

  2003cited by this paper
• Breast cancer and hormone-replacement therapy in the Million Women Study.

  2003cited by this paper
• Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited.

  2002cited by this paper
• A Unified Mechanism in the Initiation of Cancer

  2002cited by this paper
• The aflatoxin B1 formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

  2002cited by this paper
• Génotoxicité des métabolites des œstrogènes et cancers

  2002cited by this paper
• The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma.

  2002cited by this paper
• Carcinogenicity of estrogens in human breast epithelial cells 1

  2001cited by this paper
• Catechol estrogen conjugates and DNA adducts in the kidney of male Syrian golden hamsters treated with 4-hydroxyestradiol: potential biomarkers for estrogen-initiated cancer.

  2001cited by this paper
• Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

  2001cited by this paper
• NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex.

  2000cited by this paper
• A Systematic Review Of Genetic Polymorphisms and Breast Cancer Risk 1

  2000cited by this paper
• Progression of human breast cancers to the metastatic state is linked to genotypes of catechol-O-methyltransferase.

  2000cited by this paper
• Implementation and refinement of the modified-conductorlike screening quantum mechanical solvation model at the MP2 level

  2000cited by this paper
• Factors determining mutagenic potential for individual cis and trans opened benzo[c]phenanthrene diol epoxide-deoxyadenosine adducts.

  2000cited by this paper
• Calculations of Hydration Entropies of Hydrophobic, Polar, and Ionic Solutes in the Framework of the Langevin Dipoles Solvation Model

  1999cited by this paper
• Theoretical Study Related to the Carcinogenic Activity of Polycyclic Aromatic Hydrocarbon Derivatives

  1999cited by this paper
• A systematic review of genetic polymorphisms and breast cancer risk.

  1999cited by this paper
• Langevin Dipoles Model for ab Initio Calculations of Chemical Processes in Solution: Parametrization and Application to Hydration Free Energies of Neutral and Ionic Solutes and Conformational Analysis in Aqueous Solution

  1997cited by this paper
• General and Systematic Pathology

  1997cited by this paper
• Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiators.

  1997cited by this paper
• Theoretical Approach to Identify Carcinogenic Activity of Polycyclic Aromatic Hydrocarbons.

  1996cited by this paper
• Molecular characteristics of catechol estrogen quinones in reactions with deoxyribonucleosides.

  1996cited by this paper
• Molecular mechanisms of estrogen carcinogenesis.

  1996cited by this paper
• Molecular Mechanisms of Estrogen Carcinogenesis

  1996cited by this paper
• Molecular Interactions in Solution: An Overview of Methods Based on Continuous Distributions of the Solvent

  1994cited by this paper
• Identification of fatty acid hydroperoxide cofactors in the cytochrome P450-mediated oxidation of estrogens to quinone metabolites. Role and balance of lipid peroxides during estrogen-induced carcinogenesis.

  1994cited by this paper
• Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

  1991cited by this paper
• Computer Modeling of Chemical Reactions in Enzymes and Solutions

  1991cited by this paper
• Covalent nucleoside adducts of benzo[a]pyrene 7,8-diol 9,10-epoxides: structural reinvestigation and characterization of a novel adenosine adduct on the ribose moiety

  1991cited by this paper
• Extremely facile reaction between the ultimate carcinogen benzo[a]pyrene-7,8-diol 9,10-epoxide and ellagic acid

  1982cited by this paper

• Derivative-Based Non-Target Identification of DNA-Reactive Impurities with Fragment Ion Filtering

  2025cites this paper
• The COMPAS Project: A Computational Database of Polycyclic Aromatic Systems. Phase 1: cata-Condensed Polybenzenoid Hydrocarbons

  2022cites this paper
• Effect of alkyl branches on the thermal stability of quaternary ammonium cations in organic electrolytes for electrochemical double layer capacitors.

  2017cites this paper
• Determination and prediction of the binding interaction between organophosphate flame retardants and p53.

  2014cites this paper
• Potential Activity of Fevicordin-A from Phaleria macrocarpa (Scheff) Boerl. Seeds as Estrogen Receptor Antagonist Based on Cytotoxicity and Molecular Modelling Studies

  2014cites this paper
• Can the chemical reactivity of an ultimate carcinogen be related to its carcinogenicity? An application to propylene oxide.

  2013cites this paper
• Chemical Reaction of Soybean Flavonoids with DNA: A Computational Study Using the Implicit Solvent Model

  2012cites this paper
• Reactivity of bisphenol A-3,4-quinone with DNA. A quantum chemical study.

  2012cites this paper
• QSAR studies on the depuration rates of polycyclic aromatic hydrocarbons, polybrominated diphenyl ethers and polychlorinated biphenyls in mussels (Elliptio complanata)

  2011cites this paper
• Noncovalent interactions between hydroxylated polycyclic aromatic hydrocarbon and DNA: molecular docking and QSAR study.

  2011cites this paper
• Estrogenic activity of anthraquinone derivatives: in vitro and in silico studies.

  2010cites this paper
• Mechanistic insights into the Michael addition of deoxyguanosine to catechol estrogen-3,4-quinones.

  2008cites this paper
• Carcinogenicity of acrylamide: a computational study.

  2008cites this paper
• Computational Studies on Prostatic Acid Phosphatase

  2008cites this paper
• Structural features of diverse ligands influencing binding affinities to Estrogen α and Estrogen β receptors. Part I: molecular descriptors calculated from minimal energy conformation of isolated ligands

  2007cites this paper
• Construction and Validation of a RET TK Catalytic Domain by Homology Modeling

  2007cites this paper
• Carcinogenicity of benzo[a]pyrene diol epoxide stereoisomers: A linear free energy relationship study

  2006cites this paper
• Guanine alkylation by ethylene oxide: calculation of chemical reactivity.

  2006cites this paper
• Comparative Analysis of Binding Energy of Chymostatin with Human Cathepsin A and Its Homologous Proteins by Molecular Orbital Calculation

  2006cites this paper
• Chemical reactivity as a tool to study carcinogenicity: reaction between chloroethylene oxide and guanine.

  2006cites this paper
• Chemical Reactivity as a Tool to Study Carcinogenicity: Reaction Between Estradiol and Estrone 3,4-Quinones Ultimate Carcinogens and Guanine.

  2004cites this paper