The Invs gene encodes a microtubule-associated protein.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of the American Society of Nephrology

• Publication date

  2004-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/01.ASN.0000128291.30249.D0PMID 15213257
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Polycystin-1 Distribution Is Modulated by Polycystin-2 Expression in Mammalian Cells*

  2003cited by this paper
• Ciliary signaling goes down the tubes

  2003cited by this paper
• Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

  2003influential reference
• Two populations of node monocilia initiate left-right asymmetry in the mouse.

  2003cited by this paper
• The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia

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• Murine models of polycystic kidney disease: molecular and therapeutic insights.

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• Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.

  2003cited by this paper
• Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

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• Phosphoenolpyruvate-dependent Tubulin-Pyruvate Kinase Interaction at Different Organizational Levels*

  2003cited by this paper
• Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells.

  2002cited by this paper
• Interaction between metabotropic glutamate receptor 7 and alpha tubulin

  2002cited by this paper
• Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.

  2002influential reference
• Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease.

  2002cited by this paper
• The left-right determinant inversin has highly conserved ankyrin repeat and IQ domains and interacts with calmodulin

  2002cited by this paper
• Identification, genomic organization, chromosomal mapping and mutation analysis of the human INV gene, the ortholog of a murine gene implicated in left-right axis development and biliary atresia

  2002cited by this paper
• The ion channel polycystin-2 is required for left-right axis determination in mice.

  2002cited by this paper
• The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

  2002cited by this paper
• Phosphorylation of microtubule-associated protein tau by Ca2+/calmodulin-dependent protein kinase II in its tubulin binding sites.

  2002cited by this paper
• The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia.

  2002cited by this paper
• Identification of Novel Bifunctional Calmodulin-binding and Microtubule-stabilizing Motifs in STOP Proteins*

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• Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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• Polycystin: new aspects of structure, function, and regulation.

  2001cited by this paper
• The tubulin fraternity: alpha to eta.

  2001cited by this paper
• Calmodulin binds to inv protein: Implication for the regulation of inv function

  2001cited by this paper
• Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia.

  2001cited by this paper
• Molecular genetics of nephronophthisis and medullary cystic kidney disease.

  2000cited by this paper
• Conservation of the WD-repeat, microtubule-binding protein, EMAP, in sea urchins, humans, and the nematode C. elegans

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• Pyruvate kinase as a microtubule destabilizing factor in vitro.

  1999cited by this paper
• Microtubules and signal transduction.

  1999cited by this paper
• Abnormal nodal flow precedes situs inversus in iv and inv mice.

  1999cited by this paper
• Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse

  1998cited by this paper
• Microtubule dynamics in living cells.

  1998cited by this paper
• Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse

  1998influential reference
• Elongation factor-1alpha stabilizes microtubules in a calcium/calmodulin-dependent manner.

  1998cited by this paper
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  1998cited by this paper
• Disruption of Microtubules Reveals Two Independent Apical Targeting Mechanisms for G-protein-coupled Receptors in Polarized Renal Epithelial Cells*

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• The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium.

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  1976cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

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  2025cites this paper
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  2024cites this paper
• PCP protein inversin regulates testis function through changes in cytoskeletal organization of actin and microtubules.

  2022cites this paper
• Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse

  2022cites this paper
• Expression Pattern of α-Tubulin, Inversin and Its Target Dishevelled-1 and Morphology of Primary Cilia in Normal Human Kidney Development and Diseases

  2021cites this paper
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  2021cites this paper
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• The entangled relationship between cilia and actin.

  2020cites this paper
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  2020influential citation
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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