Induction of potato steroidal glycoalkaloid biosynthetic pathway by overexpression of cDNA encoding primary metabolism HMG-CoA reductase and squalene synthase

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Planta

• Publication date

  2011-12-29

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology, Environmental Science

• Identifiers
  DOI 10.1007/s00425-011-1578-6PMID 22205426
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metabolomic, Transcriptional, Hormonal, and Signaling Cross-Talk in Superroot2

  2009cited by this paper
• Dual biosynthetic pathways to phytosterol via cycloartenol and lanosterol in Arabidopsis

  2009cited by this paper
• Transcriptomic profiling of heat-stress response in potato periderm.

  2009cited by this paper
• Segregation of leptines and other glycoalkaloids inSolanum tuberosum (4x) ×S. chacoense (4x) crosses

  2008cited by this paper
• Indolic glucosinolates at the crossroads of tryptophan metabolism

  2008cited by this paper
• The Transcript and Metabolite Networks Affected by the Two Clades of Arabidopsis Glucosinolate Biosynthesis Regulators1[W]

  2008cited by this paper
• Potato glycosterol rhamnosyltransferase, the terminal step in triose side-chain biosynthesis.

  2007cited by this paper
• Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism

  2007cited by this paper
• Potato steroidal glycoalkaloid levels and the expression of key isoprenoid metabolic genes

  2007cited by this paper
• Lanosterol synthase in dicotyledonous plants.

  2006cited by this paper
• Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes.

  2006cited by this paper
• The primary in vivo steroidal alkaloid glucosyltransferase from potato.

  2006cited by this paper
• Enhanced seed phytosterol accumulation through expression of a modified HMG-CoA reductase.

  2006cited by this paper
• Lanosterol biosynthesis in plants.

  2006cited by this paper
• Metabolic compensation of steroidal glycoalkaloid biosynthesis in transgenic potato tubers: using reverse genetics to confirm the in vivo enzyme function of a steroidal alkaloid galactosyltransferase $

  2005cited by this paper
• Overexpression of squalene synthase in Eleutherococcus senticosus increases phytosterol and triterpene accumulation.

  2005cited by this paper
• Enhanced triterpene and phytosterol biosynthesis in Panax ginseng overexpressing squalene synthase gene.

  2004cited by this paper
• Responses of primary and secondary metabolism to sugar accumulation revealed by microarray expression analysis of the Arabidopsis mutant, pho3.

  2004cited by this paper
• Biosynthesis and accumulation of sterols.

  2004cited by this paper
• Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana

  2003cited by this paper
• Enhancement of seed phytosterol levels by expression of an N-terminal truncated Hevea brasiliensis (rubber tree) 3-hydroxy-3-methylglutaryl-CoA reductase.

  2003cited by this paper
• Reduction of Cholesterol and Glycoalkaloid Levels in Transgenic Potato Plants by Overexpression of a Type 1 Sterol Methyltransferase cDNA1

  2003cited by this paper
• Co-expression of N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase and C24-sterol methyltransferase type 1 in transgenic tobacco enhances carbon flux towards end-product sterols.

  2003cited by this paper
• Regulation of Squalene Synthase, a Key Enzyme of Sterol Biosynthesis, in Tobacco1

  2002cited by this paper
• Sterol C-24 Methyltransferase Type 1 Controls the Flux of Carbon into Sterol Biosynthesis in Tobacco Seed

  2002cited by this paper
• Inhibition of Squalene Synthase and Squalene Epoxidase in Tobacco Cells Triggers an Up-Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase

  2002cited by this paper
• Glycoalkaloids in potato tubers: the effect of variety and drought stress on the α‐solanine and α‐chaconine contents of potatoes

  2000cited by this paper
• Influence of high temperature and reduced irradiance on glycoalkaloid levels in potato leaves.

  2000cited by this paper
• STEROL METHYLTRANSFERASE 1 Controls the Level of Cholesterol in Plants

  2000cited by this paper
• Enzymology of phytosterol transformations.

  1999cited by this paper
• cDNA cloning of sesquiterpene cyclase and squalene synthase, and expression of the genes in potato tuber infected with Phytophthora infestans.

  1999cited by this paper
• Identification of molecular markers associated with leptine production in a population of Solanum chacoense Bitter

  1999cited by this paper
• Influence of light-enhanced glycoalkaloids on resistance of potato tubers to Fusarium sulphureum and Fusarium solani var. coeruleum

  1998cited by this paper
• BRASSINOSTEROIDS: Essential Regulators of Plant Growth and Development.

  1998cited by this paper
• Foliar leptine production in segregating F1, Inter-F1, and backcross families ofSolanum chacoense bitter

  1998cited by this paper
• Potato glycoalkaloid impairment of fungal development

  1997cited by this paper
• Cloning and expression of solanidine UDP-glucose glucosyltransferase from potato.

  1997cited by this paper
• Potato glycoalkaloids: chemistry, analysis, safety, and plant physiology

  1997cited by this paper
• Improved High-Performance Liquid Chromatographic Method for the Analysis of Potato (Solanum tuberosum) Glycoalkaloids

  1996cited by this paper
• Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis.

  1996cited by this paper
• Potato Glycoalkaloids: A Burden or a Blessing?

  1996cited by this paper
• Sterol composition and synthesis in potato tuber discs in relation to glycoalkaloid synthesis

  1996cited by this paper
• Potato glycoalkaloids: Some unanswered questions

  1996cited by this paper
• Bacterial expression of the catalytic domain of 3-hydroxy-3-methylglutaryl-CoA reductase (isoform HMGR1) from Arabidopsis thaliana, and its inactivation by phosphorylation at Ser577 by Brassica oleracea 3-hydroxy-3-methylglutaryl-CoA reductase kinase.

  1995cited by this paper
• Expression of the Hevea brasiliensis (H.B.K.) Mull. Arg. 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase 1 in Tobacco Results in Sterol Overproduction

  1995cited by this paper
• Is the Reaction Catalyzed by 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase a Rate-Limiting Step for Isoprenoid Biosynthesis in Plants?

  1995influential reference
• Glycoalkaloid concentration of potato tubers following continuous illumination

  1994cited by this paper
• Regulation of HMG-CoA reductase activity in plants.

  1994cited by this paper
• Lipid-derived signals that discriminate wound- and pathogen-responsive isoprenoid pathways in plants: methyl jasmonate and the fungal elicitor arachidonic acid induce different 3-hydroxy-3-methylglutaryl-coenzyme A reductase genes and antimicrobial isoprenoids in Solanum tuberosum L.

  1994cited by this paper
• Glycoalkaloid increase in Solarium tuberosum on exposure to light

  1993cited by this paper
• ENZYMATIC CYCLIZATION OF SQUALENE AND OXIDOSQUALENE TO STEROLS AND TRITERPENES

  1993cited by this paper
• Glycoalkaloid contents in tubers fromSolanum tuberosum populations selected for potato leafhopper resistance

  1992cited by this paper
• A versatile binary vector system with a T-DNA organisational structure conducive to efficient integration of cloned DNA into the plant genome

  1992cited by this paper
• Differential induction and suppression of potato 3-hydroxy-3-methylglutaryl coenzyme A reductase genes in response to Phytophthora infestans and to its elicitor arachidonic acid.

  1992cited by this paper
• Regulation of Glycoalkaloid Accumulation in Potato Tuber Discs

  1992cited by this paper
• Differential activation of potato 3-hydroxy-3-methylglutaryl coenzyme A reductase genes by wounding and pathogen challenge.

  1991cited by this paper
• Induction of sesquiterpene cyclase and suppression of squalene synthetase activity in elicitor-treated or fungal-infected potato tuber tissue

  1991cited by this paper
• Single nucleotide resolution of sterol regulatory region in promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductase.

  1991cited by this paper
• Transposition of the maize transposable element Ac in Solanum tuberosum

  1988cited by this paper
• The metabolism of solanidine by microsomal fractions from Solanum chacoense

  1987cited by this paper
• Segregation of leptine glycoalkaloids in Solanum chacoense bitter

  1986cited by this paper
• Dormantinol, a possible precursor in solanidine biosynthesis, from budding Veratrum grandiflorum

  1977cited by this paper
• Incorporation of14C from Acetate and Mevalonate into Rishitin and Steroid Glycoalkaloids by Potato Tuber Slices Inoculated with Phytophthora infestans

  1973cited by this paper

• Molecular Mechanisms of Dual Potato Reproduction

  2025cites this paper
• Integrative metabolomic and transcriptomic analysis provides insight into the mechanism of pigmentation in potato tuber eyes

  2025cites this paper
• Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation

  2024cites this paper
• Searching for nature-based solutions: Molecular ecology of an endangered Himalayan medicinal herb shows roadmap for conservation and sustainable utilization

  2024cites this paper
• Allelic variation in the autotetraploid potato: genes involved in starch and steroidal glycoalkaloid metabolism as a case study

  2024influential citation
• Finding the Balance: Modifying the Cholesterol and Steroidal Glycoalkaloid Synthesis Pathway in Tomato (Solanum lycopersicum L.) for human health, fruit flavor, and plant defense

  2024cites this paper
• A quest for the potato of the future: Characterization of wild tuber-bearing Solanum species for de novo domestication.

  2024cites this paper
• Combined Small RNA and Degradome Sequencing Reveals Important Roles of Light-Responsive microRNAs in Wild Potato (Solanum chacoense)

  2023cites this paper
• Metabolomic and transcriptomic analyses identify external conditions and key genes underlying high levels of toxic glycoalkaloids in tubers of stress-sensitive potato cultivars

  2023cites this paper
• GGE Biplot-Based Transcriptional Analysis of 7 Genes Involved in Steroidal Glycoalkaloid Biosynthesis in Potato (Solanum tuberosum L.)

  2023cites this paper
• Colorado potato beetle exploits frass-associated bacteria to suppress defense responses in potato plants.

  2022cites this paper
• Phased, chromosome-scale genome assemblies of tetraploid potato reveals a complex genome, transcriptome, and predicted proteome landscape underpinning genetic diversity.

  2022cites this paper
• GWAS in tetraploid potato: identification and validation of SNP markers associated with glycoalkaloid content.

  2022cites this paper
• Sustainable Use of Bioactive Compounds from Solanum Tuberosum and Brassicaceae Wastes and by-Products for Crop Protection—A Review

  2021cites this paper
• Solanum steroidal glycoalkaloids: structural diversity, biological activities, and biosynthesis.

  2021cites this paper
• Updates on steroidal alkaloids and glycoalkaloids in Solanum spp.: Biosynthesis, in vitro production and pharmacological values

  2021cites this paper
• Growth, phytochemical and gene expression changes related to the secondary metabolite synthesis of Solanum viarum Dunal

  2021cites this paper
• Biotechnological Approaches for Nutritional Improvement in Potato ( Solanum tuberosum L.)

  2021cites this paper
• Cloning, functional characterization and expression analysis of LoTPS5 from Lilium 'Siberia'.

  2020cites this paper
• Altering Potato Isoprenoid Metabolism Increases Biomass and Induces Early Flowering.

  2020cites this paper
• Genome-Wide HMG Family Investigation and Its Role in Glycoalkaloid Accumulation in Wild Tuber-Bearing Solanum commersonii

  2020influential citation
• Potato Glycoalkaloids

  2020cites this paper
• Potato

  2020cites this paper
• Altered Steroidal Glycoalkaloid (SGA) Biosynthesis in Diploid Potatoes as Induced by EMS-Mutagenesis

  2020cites this paper
• Enhanced production of celastrol in Tripterygium wilfordii hairy root cultures by overexpression of TwSQS2

  2020cites this paper
• Nutritional value of potato (Solanum tuberosum) in hot climates: anthocyanins, carotenoids, and steroidal glycoalkaloids

  2019cites this paper
• Light exposure and wounding: synergistic effects on steroidal glycoalkaloid accumulation in potato tubers during storage

  2019cites this paper
• Genetic Mapping of Steroidal Glycoalkaloids Using Selective Genotyping in Potato

  2019influential citation
• Molecular Cloning and Functional Identification of a Squalene Synthase Encoding Gene from Alfalfa (Medicago sativa L.)

  2019cites this paper
• RNA Sequencing Reveals That Both Abiotic and Biotic Stress-Responsive Genes Are Induced during Expression of Steroidal Glycoalkaloid in Potato Tuber Subjected to Light Exposure

  2019influential citation
• Growth and alkaloid production along with expression profiles of biosynthetic pathway genes in two contrasting morphotypes of prickly and prickleless Solanum viarum Dunal

  2019cites this paper
• Cloning, Expression Analysis and Functional Characterization of Squalene Synthase (SQS) from Tripterygium wilfordii

  2018cites this paper
• Biotechnological improvement of nutritional and therapeutic value of cultivated potato.

  2018cites this paper
• An update of therapeutic potential and bioanalytical aspects of steroidal glycoalkaloid (solanidine)

  2017cites this paper
• Transcript profiling of two potato cultivars during glycoalkaloid-inducing treatments shows differential expression of genes in sterol and glycoalkaloid metabolism

  2017cites this paper
• Lanosterol synthase-like is involved with differential accumulation of steroidal glycoalkaloids in potato

  2017cites this paper
• Identification of genes related to skin development in potato

  2017cites this paper
• The Solanum tuberosum KST1 partial promoter as a tool for guard cell expression in multiple plant species

  2017cites this paper
• Transcriptome analysis reveals metabolic alteration due to consecutive monoculture and abiotic stress stimuli in Rehamannia glutinosa Libosch

  2017cites this paper
• Genome diversity of tuber-bearing Solanum uncovers complex evolutionary history and targets of domestication in the cultivated potato

  2017cites this paper
• Integrated RNA-seq and sRNA-seq analysis reveals miRNA effects on secondary metabolism in Solanum tuberosum L

  2017cites this paper
• Characterization and Transcriptional Profile of Genes Involved in Glycoalkaloid Biosynthesis in New Varieties of Solanum tuberosum L.

  2016cites this paper
• Potato root system development and factors that determine its architecture.

  2016cites this paper
• GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

  2016cites this paper
• Comparative analyses of squalene synthase (SQS) proteins in poplar and pine by using bioinformatics tools

  2016cites this paper
• Next Generation Sequencing Bulk Segregant Analysis of Potato Support that Differential Flux into the Cholesterol and Stigmasterol Metabolite Pools Is Important for Steroidal Glycoalkaloid Content

  2016influential citation
• Potato tuber herbivory increases resistance to aboveground lepidopteran herbivores

  2016cites this paper
• Dissecting stylar responses to self-pollination in wild tomato self-compatible and self-incompatible species using comparative proteomics.

  2016cites this paper
• Virus-induced gene silencing of Withania somnifera squalene synthase negatively regulates sterol and defence-related genes resulting in reduced withanolides and biotic stress tolerance.

  2015cites this paper
• Identification , isolation and bioinformatic analysis of squalene sinthase-like cDNA fragments in Botryococcus terribilis AICB 870 strain Tiberiu Sz ő

  2015cites this paper
• The bitter side of the nightshades: Genomics drives discovery in Solanaceae steroidal alkaloid metabolism.

  2015cites this paper
• cDNA Cloning and Expression Analysis of Farnesyl Pyrophosphate Synthase from Ornithogalum saundersiae

  2014cites this paper
• Transcriptional expression of seven key genes involved in steroidal glycoalkaloid biosynthesis in potato microtubers

  2014cites this paper
• Comparative Expression of Key Genes Involved in Steroidal Glycoalkaloid Biosynthesis in Tubers of Two Potato Cultivars, Atlantic and Haryoung

  2014cites this paper
• Allelic variation in genes contributing to glycoalkaloid biosynthesis in a diploid interspecific population of potato

  2013cites this paper
• Retrospective View of North American Potato (Solanum tuberosum L.) Breeding in the 20th and 21st Centuries

  2013cites this paper