Modification of Lipooligosaccharide with Phosphoethanolamine by LptA in Neisseria meningitidis Enhances Meningococcal Adhesion to Human Endothelial and Epithelial Cells

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Infection and Immunity

• Publication date

  2008-09-29

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/IAI.00676-08PMID 18824535PMCID PMC2583577
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential in vitro infectious abilities of two common Japan-specific sequence-type (ST) clones of disease-associated ST-2032 and carrier-associated ST-2046 Neisseria meningitidis strains in human endothelial and epithelial cell lines.

  2008cited by this paper
• Phosphoethanolamine substitution in the lipid A of Escherichia coli O157 : H7 and its association with PmrC.

  2006cited by this paper
• O-Acetylation of the Terminal N-Acetylglucosamine of the Lipooligosaccharide Inner Core in Neisseria meningitidis

  2006cited by this paper
• Lipooligosaccharide Structure Contributes to Multiple Steps in the Virulence of Neisseria meningitidis

  2006cited by this paper
• Characterization of MspA, an Immunogenic Autotransporter Protein That Mediates Adhesion to Epithelial and Endothelial Cells in Neisseria meningitidis

  2006cited by this paper
• Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cells

  2005cited by this paper
• Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis

  2005cited by this paper
• lpt6, a Gene Required for Addition of Phosphoethanolamine to Inner-Core Lipopolysaccharide of Neisseria meningitidis and Haemophilus influenzae

  2004influential reference
• NadA Diversity and Carriage in Neisseria meningitidis

  2004cited by this paper
• Necessity of Meningococcal γ-Glutamyl Aminopeptidase for Neisseria meningitidis Growth in Rat Cerebrospinal Fluid (CSF) and CSF-Like Medium

  2004cited by this paper
• Post-translational processing of Neisseria meningitidis gamma-glutamyl aminopeptidase and its association with inner membrane facing to the cytoplasmic space.

  2004cited by this paper
• Neisseria meningitidis: an overview of the carriage state.

  2004cited by this paper
• The PmrA-Regulated pmrC Gene Mediates Phosphoethanolamine Modification of Lipid A and Polymyxin Resistance in Salmonella enterica

  2004cited by this paper
• C3 Promotes Clearance of Klebsiella pneumoniae by A549 Epithelial Cells

  2004cited by this paper
• Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells

  2004cited by this paper
• Phosphorylation of the Lipid A Region of Meningococcal Lipopolysaccharide: Identification of a Family of Transferases That Add Phosphoethanolamine to Lipopolysaccharide

  2003influential reference
• Lipooligosaccharide-Deficient Neisseria meningitidis Shows Altered Pilus-Associated Characteristics

  2003cited by this paper
• Fibronectin mediates Opc‐dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells

  2002cited by this paper
• Phase variation in meningococcal lipooligosaccharide biosynthesis genes.

  2002cited by this paper
• A co‐operative interaction between Neisseria gonorrhoeae and complement receptor 3 mediates infection of primary cervical epithelial cells

  2002cited by this paper
• The role of lipooligosaccharide in Neisseria gonorrhoeae pathogenesis of cervical epithelia: lipid A serves as a C3 acceptor molecule

  2002cited by this paper
• A broad-host-range vector of incompatibility group Q can work as a plasmid vector in Neisseria meningitidis: a new genetical tool.

  2002cited by this paper
• Identification of a gene (lpt‐3) required for the addition of phosphoethanolamine to the lipopolysaccharide inner core of Neisseria meningitidis and its role in mediating susceptibility to bactericidal killing and opsonophagocytosis

  2002influential reference
• How do extracellular pathogens cross the blood-brain barrier?

  2002cited by this paper
• The role of complement receptor 3 (CR3) in Neisseria gonorrhoeae infection of human cervical epithelia

  2001cited by this paper
• Lipopolysaccharide (LPS) labeled with Alexa 488 hydrazide as a novel probe for LPS binding studies.

  2000influential reference
• Gonococcal lipooligosaccharide is a ligand for the asialoglycoprotein receptor on human sperm

  2000cited by this paper
• Role of Lipooligosaccharide in Opa-Independent Invasion of Neisseria gonorrhoeae into Human Epithelial Cells

  2000cited by this paper
• Epidemiology and pathogenesis of Neisseria meningitidis.

  2000cited by this paper
• Interactions of pathogenic Neisseria with host cells. Is it possible to assemble the puzzle?

  1999cited by this paper
• Interaction mechanisms of encapsulated meningococci with eucaryotic cells: what does this tell us about the crossing of the blood-brain barrier by Neisseria meningitidis?

  1999cited by this paper
• Mechanisms of neisserial serum resistance

  1999cited by this paper
• The genetic basis of the phase variation repertoire of lipopolysaccharide immunotypes in Neisseria meningitidis.

  1999influential reference
• The role of neisserial Opa proteins in interactions with host cells.

  1998cited by this paper
• Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element.

  1996cited by this paper
• Capsule phase variation in Neisseria meningitidis serogroup B by slipped‐strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease

  1996cited by this paper
• Neisseria gonorrhoeae utilizes and enhances the biosynthesis of the asialoglycoprotein receptor expressed on the surface of the hepatic HepG2 cell line

  1995cited by this paper
• Opc- and pilus-dependent interactions of meningococci with human endothelial cells: molecular mechanisms and modulation by surface polysaccharides.

  1995cited by this paper
• Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis

  1994cited by this paper
• Bacterial endotoxin: molecular relationships of structure to activity and function

  1994cited by this paper
• Lipo-oligosaccharide immunotyping of Neisseria meningitidis by a whole-cell ELISA with monoclonal antibodies.

  1994cited by this paper
• Demonstration of lipooligosaccharide immunotype and capsule as virulence factors for Neisseria meningitidis using an infant mouse intranasal infection model.

  1993cited by this paper
• Meningococcal lipopolysaccharides: virulence factor and potential vaccine component.

  1993cited by this paper
• Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells

  1993influential reference
• Antibodies to N‐terminal peptides of gonococcal porin are bactericidal when gonococcal lipopolysaccharide is not sialylated

  1992cited by this paper
• The lipooligosaccharide immunotype as a virulence determinant in Neisseria meningitidis.

  1992cited by this paper
• Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by Neisseria meningitidis

  1992cited by this paper
• A comparison of the variable antigens expressed by clone IV-1 and subgroup III of Neisseria meningitidis serogroup A.

  1992cited by this paper
• The role of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells

  1991cited by this paper
• The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica

  1987cited by this paper
• Elaboration of a 3.6-kilodalton lipooligosaccharide, antibody against which is absent from human sera, is associated with serum resistance of Neisseria gonorrhoeae

  1985cited by this paper

• The multifaceted roles of phosphoethanolamine-modified lipopolysaccharides: from stress response and virulence to cationic antimicrobial resistance

  2024cites this paper
• Proteomic approach to identify host cell attachment proteins provides protective Pseudomonas aeruginosa vaccine antigen FtsZ

  2024cites this paper
• Phosphoethanolamine Transferases as Drug Discovery Targets for Therapeutic Treatment of Multi-Drug Resistant Pathogenic Gram-Negative Bacteria

  2023cites this paper
• Lipid a Phosphoethanolamine Transferase Regulation, Structure and Immune Response.

  2020cites this paper
• Genetic incorporation of non-canonical amino acid photocrosslinkers in Neisseria meningitidis: New method provides insights into the physiological function of the function-unknown NMB1345 protein

  2020cites this paper
• Predominant phosphorylation patterns in Neisseria meningitidis lipid A determined by top-down MS/MS

  2020cites this paper
• Structure-Function Relationships of the Neisserial EptA Enzyme Responsible for Phosphoethanolamine Decoration of Lipid A: Rationale for Drug Targeting

  2018cites this paper
• Transposon mutagenesis-based identification of meningococcal genes required for interactions with respiratory epithelial cells.

  2018cites this paper
• Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope

  2018influential citation
• Interactions between Pathways of the Complement System and Neisseria meningitidis

  2018cites this paper
• Pharmacophore and ligand-guided screening of antibacterial leads targeting antibiotic resistance factor in Gram-negative bacteria

  2018cites this paper
• The Meningococcal Cysteine Transport System Plays a Crucial Role in <italic toggle='yes'>Neisseria meningitidis</italic> Survival in Human Brain Microvascular Endothelial Cells

  2018cites this paper
• The Meningococcal Cysteine Transport System Plays a Crucial Role in Neisseria meningitidis Survival in Human Brain Microvascular Endothelial Cells

  2018cites this paper
• Influence of host and bacterial factors during Neisseria meningitidis colonization

  2018cites this paper
• The role of lipid a head group modification in Escherichia coli virulence and polymyxin resistance

  2017cites this paper
• Innate immune response to lipooligosaccharide: pivotal regulator of the pathobiology of invasive Neisseria meningitidis infections.

  2017cites this paper
• In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes

  2016cites this paper
• Neisseria meningitidis Translation Elongation Factor P and Its Active-Site Arginine Residue Are Essential for Cell Viability

  2016cites this paper
• The key role of the Lectin Pathway enzyme MASP-3 in the innate immune protection against Neisseria meningitides

  2016cites this paper
• Biosynthetically engineered lipopolysaccharide as vaccine adjuvant

  2015cites this paper
• Phosphoethanolamine transferases in Haemophilus ducreyi modify lipid A and contribute to human defensin resistance

  2015cites this paper
• Lipooligosaccharide Structures of Invasive and Carrier Isolates of Neisseria meningitidis Are Correlated with Pathogenicity and Carriage*

  2015cites this paper
• Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM l-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial Cells

  2015cites this paper
• The Role of Oxidoreductases in Determining the Function of the Neisserial Lipid A Phosphoethanolamine Transferase Required for Resistance to Polymyxin

  2014influential citation
• Type IV Pilus Assembly Proficiency and Dynamics Influence Pilin Subunit Phospho-Form Macro- and Microheterogeneity in Neisseria gonorrhoeae

  2014cites this paper
• Lipid A Is More than Acyl Chains

  2014cites this paper
• Analysis of the immunological and functional features of the Neisserial Heparin Binding Antigen ( NHBA )

  2014cites this paper
• Analysis of the immunological and functional features of the Neisserial Heparin Binding Antigen (NHBA)

  2014cites this paper
• Transcriptional Profiling of Neisseria meningitidis Interacting with Human Epithelial Cells in a Long-Term In Vitro Colonization Model

  2013cites this paper
• Trascriptome analysis and functional genomics of Neisseria meningitidis in human blood

  2012cites this paper
• Cloning, expression, purification and crystallization of an endotoxin-biosynthesis enzyme from Neisseria meningitidis.

  2012cites this paper
• Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2007-2008.

  2012cites this paper
• Meningococcal PilV Potentiates Neisseria meningitidis Type IV Pilus-Mediated Internalization into Human Endothelial and Epithelial Cells

  2012cites this paper
• Phosphoethanolamine Residues on the Lipid A Moiety of Neisseria gonorrhoeae Lipooligosaccharide Modulate Binding of Complement Inhibitors and Resistance to Complement Killing

  2012cites this paper
• Meningococcal ligands and molecular targets of the host.

  2012cites this paper
• A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis

  2012influential citation
• Characterization of DsbD in Neisseria meningitidis

  2011influential citation
• Genetics and Biosynthesis of Lipid A

  2011cites this paper
• Meningococcal Internalization into Human Endothelial and Epithelial Cells Is Triggered by the Influx of Extracellular l-Glutamate via GltT l-Glutamate ABC Transporter in Neisseria meningitidis

  2010cites this paper
• Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis.

  2009cites this paper
• iology and pathogenesis of the evolutionarily successful , obligate human acterium Neisseria meningitidis

  2009cites this paper
• [Analyses of the pathogenesis in Neisseria meningitidis].

  2009cites this paper
• Genome Sequence of the Endosymbiont Rickettsia peacockii and Comparison with Virulent Rickettsia rickettsii: Identification of Virulence Factors

  2009cites this paper