Mice without the Regulator Gene Rsc1A1 Exhibit Increased Na+-d-Glucose Cotransport in Small Intestine and Develop Obesity

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Molecular and Cellular Biology

• Publication date

  2005-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.25.1.78-87.2005PMID 15601832PMCID PMC538757
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A glucose sensor hiding in a family of transporters

  2003cited by this paper
• A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line.

  2003cited by this paper
• Downregulation of the Na+-D-glucose Cotransporter SGLT1 by Protein RS1 (RSC1A1) is Dependent on Dynamin and Protein Kinase C

  2003cited by this paper
• Normal kinetics of intestinal glucose absorption in the absence of GLUT2: Evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum

  2001cited by this paper
• HuR binds a cyclic nucleotide‐dependent, stabilizing domain in the 3′ untranslated region of Na+/glucose cotransporter (SGLT1) mRNA

  2001cited by this paper
• The Plasma Membrane-associated Protein RS1 Decreases Transcription of the Transporter SGLT1 in Confluent LLC-PK1 Cells*

  2001cited by this paper
• Glucosensing neurons do more than just sense glucose

  2001cited by this paper
• Transcriptional regulation of the ovine intestinal Na+/glucose cotransporter SGLT1 gene. Role of HNF-1 in glucose activation of promoter function.

  2001cited by this paper
• Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1.

  2000cited by this paper
• Na+‐Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. Part 4. Synthesis and Pharmacological Properties of 4′‐Dehydroxyphlorizin Derivatives Substituted on the B Ring.

  2000cited by this paper
• The transport modifier RS1 is localized at the inner side of the plasma membrane and changes membrane capacitance.

  2000cited by this paper
• PKC regulates turnover rate of rabbit intestinal Na+-glucose transporter expressed in COS-7 cells.

  1999cited by this paper
• Cloning and characterization of the transport modifier RS1 from rabbit which was previously assumed to be specific for Na+-D-glucose cotransport.

  1999cited by this paper
• Na(+)-glucose cotransporter (SGLT) inhibitors as antidiabetic agents. 4. Synthesis and pharmacological properties of 4'-dehydroxyphlorizin derivatives substituted on the B ring.

  1999cited by this paper
• Identification and Characterization of Glucoresponsive Neurons in the Enteric Nervous System

  1999cited by this paper
• PKC regulates turnover rate of rabbit intestinal Na+-glucose transporter expressed in COS-7 cells.

  1999cited by this paper
• Cholecystokinin Decreases Intestinal Hexose Absorption by a Parallel Reduction in SGLT1 Abundance in the Brush-Border Membrane*

  1998cited by this paper
• Specific features of glycogen metabolism in the liver.

  1998cited by this paper
• Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature.

  1998cited by this paper
• Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature.

  1998cited by this paper
• Circadian Periodicity of Intestinal Na+/Glucose Cotransporter 1 mRNA Levels Is Transcriptionally Regulated*

  1998cited by this paper
• Acute and chronic exposure of rat intestinal mucosa to dextran promotes SGLT1‐mediated glucose transport

  1998cited by this paper
• Upregulation of SGLT-1 transport activity in rat jejunum induced by GLP-2 infusion in vivo.

  1997cited by this paper
• Upregulation of SGLT-1 transport activity in rat jejunum induced by GLP-2 infusion in vivo.

  1997cited by this paper
• Expression of the Na+‐d‐Glucose Cotransporter SGLT1 in Neurons

  1997cited by this paper
• Mechanism of beta-adrenergic agonist-induced transmural transport of glucose in rat small intestine. Regulation of phosphorylation of SGLT1 controls the function.

  1997cited by this paper
• A new role for enteric glucagon‐37: acute stimulation of glucose absorption in rat small intestine

  1997cited by this paper
• Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

  1997cited by this paper
• Regulation of lipogenic enzyme expression by glucose in liver and adipose tissue: a review of the potential cellular and molecular mechanisms.

  1996cited by this paper
• Acute increase by portal insulin in intestinal glucose absorption via hepatoenteral nerves in the rat.

  1996cited by this paper
• The Human Gene of a Protein That Modifies Na+-d-Glucose Co-Transport

  1996cited by this paper
• Regulation of Na+/Glucose Cotransporter Expression by Protein Kinases in Xenopus laevis Oocytes*

  1996cited by this paper
• Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity.

  1995cited by this paper
• Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

  1995cited by this paper
• Molecular physiology of sodium-glucose cotransporters.

  1994cited by this paper
• Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter.

  1993cited by this paper
• Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver.

  1992cited by this paper
• Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene.

  1991cited by this paper
• Specific regulation of intestinal nutrient transporters by their dietary substrates.

  1989cited by this paper
• Human obesity.

  1987cited by this paper
• Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity.

  1987cited by this paper
• The Fire of Life

  1962cited by this paper
• New methods for calculating metabolic rate with special reference to protein metabolism

  1949cited by this paper

• The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications

  2025cites this paper
• Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome.

  2024cites this paper
• The β2-adrenergic receptor in the apical membrane of intestinal enterocytes senses sugars to stimulate glucose uptake from the gut

  2023cites this paper
• Obesity and overweight are linked to increased sodium‐glucose cotransporter 1 and glucose transporter 5 levels in duodenum

  2023cites this paper
• Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice

  2023cites this paper
• Sodium-Glucose Co-Transporters Family: Current Evidence, Clinical Applications and Perspectives.

  2023cites this paper
• Altered intestinal epithelial nutrient transport: an underappreciated factor in obesity modulated by diet and microbiota.

  2021cites this paper
• Glucose transporters in the small intestine in health and disease

  2020cites this paper
• Glucose transporters in brain in health and disease

  2020cites this paper
• Mechanisms of Control of Type 2 Diabetes with Gastric Bypass

  2020cites this paper
• Phenolic acids from Coffea arabica L. suppress intestinal uptake of glucose and cholesterol.

  2020cites this paper
• Cardiometabolic Syndrome: An Update on Available Mouse Models

  2020cites this paper
• Artificial selection drives differential gene expression during pig domestication.

  2019cites this paper
• A Modified Tripeptide Motif of RS1 (RSC1A1) Down-Regulates Exocytotic Pathways of Human Na+-d-glucose Cotransporters SGLT1, SGLT2, and Glucose Sensor SGLT3 in the Presence of Glucose

  2018cites this paper
• Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk

  2018cites this paper
• Increased Rates of Meal Absorption Do Not Explain Elevated 1-Hour Glucose in Subjects With Normal Glucose Tolerance

  2018cites this paper
• RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury

  2018influential citation
• Maternal Methyl Donor Supplementation during Gestation Counteracts the Bisphenol A-Induced Impairment of Intestinal Morphology, Disaccharidase Activity, and Nutrient Transporters Gene Expression in Newborn and Weaning Pigs

  2017cites this paper
• Influence of Lactase on the In Vitro and In Vivo Antiglycaemic Effects of Onion Flavonoids

  2017cites this paper
• Saving the sweetness: renal glucose handling in health and disease.

  2017cites this paper
• Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals

  2017cites this paper
• Physiologic changes in obesity and patient preparation for bariatric surgery

  2017cites this paper
• Intestinal SGLT 1 in metabolic health and disease

  2016cites this paper
• Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

  2016cites this paper
• A Maternal High-Energy Diet Promotes Intestinal Development and Intrauterine Growth of Offspring

  2016influential citation
• Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase

  2016cites this paper
• Early postnatal feed restriction reduces liver connective tissue levels and affects H3K9 acetylation state of regulated genes associated with protein metabolism in low birth weight pigs.

  2016cites this paper
• An obese brain and an inflamed body: Central and peripheral consequences of obesity

  2016cites this paper
• Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus

  2016cites this paper
• Phosphorylation of RS1 (RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption

  2016influential citation
• Intestinal SGLT1 in metabolic health and disease.

  2016cites this paper
• Accelerated intestinal glucose absorption in morbidly obese humans: relationship to glucose transporters, incretin hormones, and glycemia.

  2015cites this paper
• Sodium-glucose cotransport

  2015cites this paper
• Leptin resistance and diet-induced obesity: central and peripheral actions of leptin.

  2015cites this paper
• Effects of maternal over- and undernutrition on intestinal morphology, enzyme activity, and gene expression of nutrient transporters in newborn and weaned pigs.

  2014cites this paper
• Modulation of olfactory sensitivity and glucose-sensing by the feeding state in obese Zucker rats

  2014cites this paper
• Renal and Extrarenal Effects of Gum Arabic (Acacia Senegal) - What Can be Learned from Animal Experiments?

  2013cites this paper
• The gut as a sensory organ

  2013cites this paper
• Role of the apical and basolateral domains of the enterocyte in the regulation of cholesterol transport by a high glucose concentration.

  2013cites this paper
• Duodenal-Jejunal Bypass Improves Glycemia and Decreases SGLT1-Mediated Glucose Absorption in Rats With Streptozotocin-Induced Type 2 Diabetes

  2013cites this paper
• Maternal protein restriction during pregnancy affects gene expression and immunolocalization of intestinal nutrient transporters in rats.

  2013cites this paper
• Role of the Transporter Regulator Protein (RS1) in the Modulation of Concentrative Nucleoside Transporters (CNTs) in Epithelia

  2012cites this paper
• Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization.

  2012cites this paper
• LITHUANIAN UNIVERSITY OF HEALTH SCIENCES MEDICAL ACADEMY

  2011cites this paper
• A genome-wide shRNA screen for new OxPhos related genes.

  2011cites this paper
• Rapid Upregulation of Sodium-Glucose Transporter SGLT1 in Response to Intestinal Sweet Taste Stimulation

  2010cites this paper
• Restricted feeding phase shifts clock gene and sodium glucose cotransporter 1 (SGLT1) expression in rats.

  2010cites this paper
• Downregulation of Mouse Intestinal Na+-coupled Glucose Transporter SGLT1 by Gum Arabic (Acacia Senegal)

  2010cites this paper
• Novel Shuttling Domain in a Regulator (RSC1A1) of Transporter SGLT1 Steers Cell Cycle‐Dependent Nuclear Location

  2009cites this paper
• Regulação da Absorção Intestinal de Glicose: Uma Breve Revisão

  2009cites this paper
• Mechanism and Control of Nuclear-Cytoplasmic Translocation of the Transporter Regulator RS1 Mechanismus und Kontrolle der Translokation der Transporterregulator RS1 zwischen Kern und Zytoplasma

  2009cites this paper
• Impact of Roux-en-Y gastric bypass surgery on rat intestinal glucose transport.

  2009cites this paper
• Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors.

  2009cites this paper
• Capsaicin-sensitive vagal afferents modulate posttranscriptional regulation of the rat Na+/glucose cotransporter SGLT1.

  2008cites this paper
• Defining the transcriptional regulation of the intestinal sodium-glucose cotransporter using RNA-interference mediated gene silencing.

  2008cites this paper
• Scientific Board of the FMP

  2007cites this paper
• Tripeptides of RS1 (RSC1A1) Inhibit a Monosaccharide-dependent Exocytotic Pathway of Na+-d-Glucose Cotransporter SGLT1 with High Affinity*

  2007cites this paper
• The Human Obesity Gene Map: The 2005 Update

  2006cites this paper
• RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1.

  2006cites this paper
• RS 1 ( RSC 1 A 1 ) regulates the exocytotic pathway of Na-D-glucose cotransporter SGLT 1

  2006cites this paper
• Intestinal sugar transport.

  2006cites this paper
• Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus.

  2006cites this paper