Randomized Study to Evaluate the Relation Between Oral Isosorbide Dinitrate Dosing Interval and the Development of Early Tolerance to Its Effect on Left Ventricular Filling Pressure in Patients With Chronic Heart Failure

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Circulation

• Publication date

  1991-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.CIR.84.5.2040PMID 1934379
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tolerance to organic nitrates: evidence, mechanisms, clinical relevance, and strategies for prevention.

  1991cited by this paper
• Tolerance to intravenous nitroglycerin in patients with congestive heart failure: role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine.

  1990cited by this paper
• The daylong pattern of the antianginal effect of long-term three times daily administered isosorbide dinitrate.

  1990cited by this paper
• Resistance to isosorbide dinitrate in patients with severe chronic heart failure: incidence and attempt at hemodynamic prediction.

  1988cited by this paper
• Prevention and reversal of nitrate tolerance in patients with congestive heart failure.

  1987cited by this paper
• Hemodynamic effects of intermittent transdermal nitroglycerin in chronic congestive heart failure.

  1987cited by this paper
• Effect of intervals between doses on the development of tolerance to isosorbide dinitrate.

  1987cited by this paper
• Mechanism of vasodilation by nitrates: role of cyclic GMP.

  1987cited by this paper
• Incidence of early tolerance to hemodynamic effects of continuous infusion of nitroglycerin in patients with coronary artery disease and heart failure.

  1987cited by this paper
• Early tolerance to hemodynamic effects of high dose transdermal nitroglycerin in responders with severe chronic heart failure.

  1987cited by this paper
• Hemodynamic factors limiting the response to transdermal nitroglycerin in severe chronic congestive heart failure.

  1987cited by this paper
• Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study.

  1986cited by this paper
• Rapidly developing tolerance to transdermal nitroglycerin in congestive heart failure.

  1986cited by this paper
• Tolerance to organic nitrates

  1986cited by this paper
• Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure

  1986cited by this paper
• Hemodynamic and hormonal effects of high-dose transdermal nitroglycerin in patients with chronic congestive heart failure.

  1985cited by this paper
• Hemodynamic changes mimicking a vasodilator drug response in the absence of drug therapy after right heart catheterization in patients with chronic heart failure.

  1985cited by this paper
• Relation of right ventricular ejection fraction to exercise capacity in chronic left ventricular failure.

  1984cited by this paper
• Acute hemodynamic effect of oral nifedipine in severe chronic congestive heart failure.

  1983cited by this paper
• Cardiac output by thermodilution technique. Effect of injectate's volume and temperature on accuracy and reproducibility in the critically Ill patient.

  1983cited by this paper
• Tolerance to isosorbide dinitrate: rate of development and reversal.

  1983cited by this paper
• Improved Exercise Capacity and Differing Arterial and Venous Tolerance During Chronic Isosorbide Dinitrate Therapy for Congestive Heart Failure

  1983cited by this paper
• Dyspnea on exertion. Is it the heart or the lungs?

  1982cited by this paper
• Glyceryl Trinitrate (Nitroglycerin) Ointment and Isosorbide Dinitrate: A Review of their Pharmacological Properties and Therapeutic Use

  1982cited by this paper
• Oral isosorbide dinitrate in angina pectoris: comparison of duration of action an dose-response relation during acute and sustained therapy.

  1982cited by this paper
• Improvement in supine bicycle exercise performance in refractory congestive heart failure after isosorbide dinitrate: radionuclide and hemodynamic evaluation of acute effects.

  1982cited by this paper
• Kinetics of isosorbide dinitrate and relationships to pharmacological effects.

  1981cited by this paper
• Plasma concentrations of isosorbide dinitrate and its metabolites after chronic high oral dosage in man.

  1978cited by this paper
• GLC determination of nitroglycerin and isosorbide dinitrate in human plasma.

  1973cited by this paper
• Tolerance to the vascular effects of glyceryl trinitrate.

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  2018cites this paper
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  2015cites this paper
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  2015influential citation
• Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications.

  2015cites this paper
• Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial.

  2014cites this paper
• Nitrate therapy for heart failure: benefits and strategies to overcome tolerance.

  2013cites this paper
• Efficacy of the long-acting nitro vasodilator pentaerithrityl tetranitrate in patients with chronic stable angina pectoris receiving anti-anginal background therapy with beta-blockers: a 12-week, randomized, double-blind, placebo-controlled trial

  2013cites this paper
• Stimulators and Activators of Soluble Guanylate Cyclase: Review and Potential Therapeutic Indications

  2012cites this paper
• Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction- A Review of Literature

  2010cites this paper
• Vasoprotektive Effekte des nicht - selektiven Endothelin-1 - Rezeptorantagonisten Bosentan auf die Gefäßreagibilität und endotheliale Superoxidanionenbildung nitrattoleranter Ratten

  2009cites this paper
• Endothelial dysfunction in heart failure and ischemic heart disease: rationale for the clinical use of mononitrates

  2007cites this paper
• Nitrates and Left Ventricular Dysfunction

  2007cites this paper
• Effects of nitrates and hydralazine in heart failure: clinical evidence before the african american heart failure trial.

  2005cites this paper
• Nitrates in congestive heart failure

  2004cites this paper
• A nitric oxide‐releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure

  2004cites this paper
• Haemodynamic evaluation of two regimens of molsidomine in patients with chronic congestive heart failure

  2004cites this paper
• Survey of the use of organic nitrates for the treatment of chronic congestive heart failure in the United States.

  2004cites this paper
• Potential role of type 5 phosphodiesterase inhibition in the treatment of congestive heart failure.

  2003cites this paper
• Safety of nitrate withdrawal in angina-free and hemodynamically stable patients with coronary artery disease.

  2003cites this paper
• Pre- and afterload reduction in chronic mitral regurgitation: a double-blind randomized placebo-controlled trial of the acute and 2 weeks' effect of nifedipine or isosorbide dinitrate treatment on left ventricular function and the severity of mitral regurgitation.

  2003cites this paper
• Role of ETA receptors in the regulation of vascular reactivity in rats with congestive heart failure

  2000cites this paper
• Role of ET(A) receptors in the regulation of vascular reactivity in rats with congestive heart failure.

  2000cites this paper
• Response to changing plasma concentrations of isosorbide‐bound no2 during acute and sustained treatment with isosorbide dinitrate in patients with coronary artery disease

  2000cites this paper
• Double-blind, placebo-controlled study to evaluate the effect of organic nitrates in patients with chronic heart failure treated with angiotensin-converting enzyme inhibition.

  1999cites this paper
• The role of organic nitrates in the treatment of heart failure.

  1999cites this paper
• Angiotensin-Converting Enzyme Inhibition Nitrates in Patients With Chronic Heart Failure Treated With Double-Blind , Placebo-Controlled Study to Evaluate the Effect of Organic

  1999cites this paper
• Tolerance: An Historical Overview

  1998cites this paper
• La tolerancia a los nitratos: un problema práctico

  1997cites this paper
• [Nitric oxide donors in therapy of chronic heart failure].

  1997cites this paper
• NO-Donoren in der Therapie der chronischen Herzinsuffizienz

  1997cites this paper
• Nitrates in the treatment of congestive heart failure.

  1996cites this paper
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  1996cites this paper
• Therapy of angina pectoris with long-acting nitrates: which agent and when?

  1996cites this paper
• Medical therapy and prognosis in chronic heart failure. Lessons from clinical trials.

  1995cites this paper
• Anti-ischemic effects of first and second dose of 20 mg isosorbide dinitrate administered 5 hours apart: Attenuation of effects despite rising plasma concentration

  1995influential citation
• Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure.

  1995cites this paper
• Thiol compounds and organic nitrates.

  1995cites this paper
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  1995cites this paper
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  1994cites this paper
• Vasodilators and inotropic agents in the treatment of congestive heart failure.

  1994cites this paper
• Effects of continuous intravenous infusion of isosorbide dinitrate on development of tolerance to vasodilating action in human epicardial coronary arteries.

  1994cites this paper
• Haemodynamic effects of glyceryl trinitrate during continuous 24 hour infusion in patients with heart failure.

  1994cites this paper
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  1994cites this paper
• Phenomenon of nitrate tolerance.

  1994cites this paper
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  1993cites this paper
• The development of positive inotropic agents for chronic heart failure: how have we gone astray?

  1993cites this paper
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  1993cites this paper
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  1992cites this paper
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  1992cites this paper
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  1992cites this paper
• Persistent hemodynamic improvement with short-term nitrate therapy in patients with chronic congestive heart failure already treated with captopril.

  1992cites this paper
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  1991cites this paper