Identification of Genes Regulated by Memantine and MK-801 in Adult Rat Brain by cDNA Microarray Analysis

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Neuropsychopharmacology

• Publication date

  2004-02-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.npp.1300398PMID 14970830
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Memantine. Merz.

  2002cited by this paper
• Rab GTPases, intracellular traffic and disease.

  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
• Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex.

  2000cited by this paper
• Role of rab GDP dissociation inhibitor alpha in regulating plasticity of hippocampal neurotransmission.

  2000cited by this paper
• Prostanoid receptors: structures, properties, and functions.

  1999cited by this paper
• NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders.

  1999influential reference
• Antidepressants for the new millennium.

  1999cited by this paper
• Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo

  1999cited by this paper
• Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data.

  1999cited by this paper
• Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat.

  1998cited by this paper
• Glutamate in CNS disorders as a target for drug development: an update.

  1998cited by this paper
• Rab proteins.

  1998cited by this paper
• Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease.

  1997cited by this paper
• NF-kB: a crucial transcription factor for glial and neuronal cell function

  1997cited by this paper
• NF-kappa B: a crucial transcription factor for glial and neuronal cell function.

  1997cited by this paper
• Enhancement of immunoreactivity for NF-κB in the hippocampal formation and cerebral cortex of Alzheimer's disease

  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Rab GDP Dissociation Inhibitor: Putting Rab GTPases in the Right Place (*)

  1995cited by this paper
• Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons.

  1995cited by this paper
• Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.

  1994cited by this paper
• Investigations of neurotoxicity and neuroprotection within the nucleus basalis of the rat.

  1994cited by this paper
• Function and activation of NF-kappa B in the immune system.

  1994cited by this paper
• Induction of c-fos and CRF mRNA by MK-801 in the parvocellular paraventricular nucleus of the rat hypothalamus.

  1994cited by this paper
• NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993influential reference
• Memantine in the treatment of mild to moderate dementia syndrome. A double-blind placebo-controlled study.

  1992cited by this paper
• Rapid induction in regenerating liver of RL/IF-1 (an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex

  1992cited by this paper
• Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

  1991cited by this paper
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  1991influential reference
• MK‐801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex

  1991cited by this paper
• Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs.

  1989cited by this paper
• Glutamate neurotoxicity and diseases of the nervous system.

  1988cited by this paper
• Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

  1988cited by this paper
• The novel anticonvulsant MK‐801 binds to the activated state of the N‐methyl‐d‐aspartate receptor in rat brain

  1987cited by this paper
• Excitatory amino acid antagonists as novel anticonvulsants.

  1986cited by this paper
• The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

  1986cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
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  1970cited by this paper

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  2022cites this paper
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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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