Neuropeptide Y administration into the amygdala suppresses ethanol drinking in alcohol-preferring (P) rats following multiple deprivations.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Pharmacology, Biochemistry and Behavior

• Publication date

  2008-09-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/j.pbb.2008.04.005PMID 18499241PMCID PMC2474782
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The genetics of alcoholism

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  2005influential reference
• Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence.

  2005influential reference
• Effects of neuropeptide Y and corticotropin-releasing factor on ethanol intake in Wistar rats: interaction with chronic ethanol exposure.

  2005cited by this paper
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  2005influential reference
• Neuropeptide Y in the paraventricular nucleus of the hypothalamus increases ethanol intake in high- and low-alcohol-drinking rats.

  2004cited by this paper
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  2004cited by this paper
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  2003influential reference
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  2003cited by this paper
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  2002cited by this paper
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  2001influential reference
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  2001cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Guide for the Care and Use of Laboratory Animals

  1996cited by this paper
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  1995cited by this paper
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  1993influential reference
• The role of the amygdala in fear and anxiety.

  1992cited by this paper
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  1992cited by this paper
• The long-term course of treated alcoholism: I. Mortality, relapse and remission rates and comparisons with community controls.

  1991cited by this paper
• Chronic ethanol tolerance through free-choice drinking in the P line of alcohol-preferring rats.

  1987cited by this paper
• Effects of scheduled access on ethanol intake by the alcohol-preferring (P) line of rats.

  1986cited by this paper
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  1986cited by this paper
• Feeding and drinking elicited by central injection of neuropeptide Y: evidence for a hypothalamic site(s) of action.

  1985influential reference
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• Induction of dependence on ethanol by free-choice drinking in alcohol-preferring rats.

  1982cited by this paper
• Progress toward a voluntary oral consumption model of alcoholism.

  1979cited by this paper

• Synaptic Effects Induced by Alcohol.

  2023cites this paper
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  2021cites this paper
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  2020influential citation
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  2019cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Rodent models for compulsive alcohol intake.

  2014cites this paper
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  2014cites this paper
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  2013cites this paper
• Synaptic effects induced by alcohol.

  2013cites this paper
• The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides.

  2012cites this paper
• Corticotropin-releasing factor (CRF) and neuropeptide Y (NPY): effects on inhibitory transmission in central amygdala, and anxiety- & alcohol-related behaviors.

  2012cites this paper
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  2012cites this paper
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• Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.

  2012cites this paper
• Neuropeptide Y (NPY) in the extended amygdala is recruited during the transition to alcohol dependence.

  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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  2010cites this paper
• [Role of endogenous neuropeptides in the pathomechanism of alcohol addiction].

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