Emodin attenuates calcium overload and endoplasmic reticulum stress in AR42J rat pancreatic acinar cells.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Molecular Medicine Reports

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/mmr.2013.1773PMID 24190079
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Emodin on Endoplasmic Reticulum Stress in Rats with Severe Acute Pancreatitis

  2013cited by this paper
• Neuroprotective effects of black soybean anthocyanins via inactivation of ASK1-JNK/p38 pathways and mobilization of cellular sialic acids.

  2012cited by this paper
• The role of calcium in acute pancreatitis.

  2012cited by this paper
• The ER chaperone GRP78 is associated with the severity of cerulein-induced pancreatic inflammation via regulating apoptosis of pancreatic acinar cells.

  2012cited by this paper
• New insights into translational regulation in the endoplasmic reticulum unfolded protein response.

  2012cited by this paper
• Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice

  2012cited by this paper
• Emodin promoted pancreatic claudin-5 and occludin expression in experimental acute pancreatitis rats.

  2012cited by this paper
• Endoplasmic reticulum stress induced by surfactant protein C BRICHOS mutants promotes proinflammatory signaling by epithelial cells.

  2011cited by this paper
• Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.

  2011cited by this paper
• Early Management of Severe Acute Pancreatitis

  2011cited by this paper
• Emodin down-regulates expression of TRPV1 mRNA and its function in DRG neurons in vitro.

  2010cited by this paper
• Inflammation and immunosuppression in severe acute pancreatitis.

  2010cited by this paper
• Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.

  2010cited by this paper
• Pancreatic acinar cell: new insights into the control of secretion.

  2010cited by this paper
• Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells

  2009cited by this paper
• Up-regulation of Toll-like receptor 4 was suppressed by emodin and baicalin in the setting of acute pancreatitis.

  2009cited by this paper
• The acinar cell and early pancreatitis responses.

  2009cited by this paper
• Mechanisms of therapeutic effects of rhubarb on gut origin sepsis.

  2009cited by this paper
• Endoplasmic reticulum stress and the pancreatic acinar cell

  2008cited by this paper
• Secretagogues differentially activate endoplasmic reticulum stress responses in pancreatic acinar cells.

  2007cited by this paper
• The Effect of Emodin-Assisted Early Enteral Nutrition on Severe Acute Pancreatitis and Secondary Hepatic Injury

  2007cited by this paper
• Calcium signalling and pancreatic cell death: apoptosis or necrosis?

  2007cited by this paper
• Ca2+ signalling and pancreatitis: effects of alcohol, bile and coffee.

  2006cited by this paper
• Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis.

  2006cited by this paper
• Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis.

  2006cited by this paper
• Role of Ca2+ in pancreatic cell death induced by alcohol metabolites

  2006cited by this paper
• NADPH oxidase and apoptosis in cerulein-stimulated pancreatic acinar AR42J cells.

  2005cited by this paper
• Ethanol toxicity in pancreatic acinar cells: mediation by nonoxidative fatty acid metabolites.

  2004cited by this paper
• Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

  2003cited by this paper
• Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells.

  2002cited by this paper
• Regulation of cell proliferation, inflammatory cytokine production and calcium mobilization in primary human T lymphocytes by emodin from Polygonum hypoleucum Ohwi

  2001cited by this paper

• Therapeutic Potentials of Phytochemicals in Pancreatitis: Targeting Calcium Signaling, Ferroptosis, microRNAs, and Inflammation with Drug-Likeness Evaluation

  2025cites this paper
• Artesunate protects against a mouse model of cerulein and lipopolysaccharide-induced acute pancreatitis by inhibiting TLR4-dependent autophagy

  2024cites this paper
• Rhei Radix et Rhizoma and its anthraquinone derivatives: Potential candidates for pancreatitis treatment.

  2024cites this paper
• Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic Pancreatitis

  2023cites this paper
• Targeting signaling pathways in osteosarcoma: Mechanisms and clinical studies

  2023cites this paper
• Determination of the components of danyikangtai powder into the plasma and its pharmacodynamic study

  2022cites this paper
• Natural Chinese herbs for the prevention and treatment of acute pancreatitis: a narrative review

  2022cites this paper
• Pitfalls in AR42J-model of cerulein-induced acute pancreatitis

  2021cites this paper
• In Vitro and in Vivo Biological Investigations of Camphene and Its Mechanism Insights: A Review

  2021cites this paper
• Antioxidant Therapy in Pancreatitis

  2021cites this paper
• Chaiqin chengqi decoction alleviates severe acute pancreatitis associated acute kidney injury by inhibiting endoplasmic reticulum stress and subsequent apoptosis.

  2020cites this paper
• Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway

  2019cites this paper
• Genistein protects against acute pancreatitis via activation of an apoptotic pathway mediated through endoplasmic reticulum stress in rats.

  2019cites this paper
• Quercetin 3-O-xyloside ameliorates acute pancreatitis in vitro via the reduction of ER stress and enhancement of apoptosis.

  2019cites this paper
• Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis

  2019cites this paper
• Inhibition of the dephosphorylation of eukaryotic initiation factor 2α ameliorates murine experimental pancreatitis.

  2019cites this paper
• Emodin exerts protective effect against palmitic acid-induced endoplasmic reticulum stress in HepG2 cells

  2019cites this paper
• Reciprocal Feedback Loop of the MALAT1-MicroRNA-194-YAP1 Pathway Regulates Progression of Acute Pancreatitis

  2019cites this paper
• Chrysophanol inhibits endoplasmic reticulum stress in cerebral ischemia and reperfusion mice

  2018cites this paper
• Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells

  2018cites this paper
• Phytoceuticals in Acute Pancreatitis: Targeting the Balance between Apoptosis and Necrosis

  2018cites this paper
• Thioredoxin silencing-induced cardiac supercontraction occurs through endoplasmic reticulum stress and calcium overload in chicken.

  2018cites this paper
• Emodin in Severe Acute Pancreatitis Treatment

  2017cites this paper
• The Pathophysiological Mechanism of Severe Acute Pancreatitis

  2017cites this paper
• Chinese Herbal Medicines Attenuate Acute Pancreatitis: Pharmacological Activities and Mechanisms

  2017influential citation
• Heat Shock Factor 1 Inhibits the Expression of Suppressor of Cytokine Signaling 3 in Cerulein-Induced Acute Pancreatitis

  2017cites this paper
• Pharmacological Properties of Emodin – Anthraquinone Derivatives

  2017cites this paper
• Endoplasmic reticulum stress is activated in acute pancreatitis

  2016cites this paper
• The toll-like receptor 4 antagonist transforming growth factor-β-activated kinase(TAK)-242 attenuates taurocholate-induced oxidative stress through regulating mitochondrial function in mice pancreatic acinar cells.

  2016cites this paper
• TRAM1 protects AR42J cells from caerulein-induced acute pancreatitis through ER stress-apoptosis pathway

  2016cites this paper
• Necroptosis: a potential, promising target and switch in acute pancreatitis

  2015cites this paper
• Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.

  2015cites this paper
• Endoplasmic reticulum stress signaling in mammalian oocytes and embryos: life in balance.

  2015cites this paper
• Investigation on the spectrum-effect relationships of Da-Huang-Fu-Zi-Tang in rats by UHPLC-ESI-Q-TOF-MS method.

  2014cites this paper