Regulatory role of PGC-1α/PPAR signaling in skeletal muscle metabolic recruitment during cold acclimation

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Experimental Biology

• Publication date

  2013-11-15

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1242/jeb.089334PMID 23948478
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• L-Arginine enhances glucose and lipid metabolism in rat L6 myotubes via the NO/ c-GMP pathway.

  2013cited by this paper
• Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation

  2013influential reference
• Chronic cold acclimation increases thermogenic capacity, non-shivering thermogenesis and muscle citrate synthase activity in both wild-type and brown adipose tissue deficient mice.

  2012cited by this paper
• Metabolic fuels: regulating fluxes to select mix

  2011cited by this paper
• Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1α and AMPKα.

  2011cited by this paper
• Low Levels of Physical Activity Increase Metabolic Responsiveness to Cold in a Rat (Rattus fuscipes)

  2010cited by this paper
• Increased fatigue resistance linked to Ca2+‐stimulated mitochondrial biogenesis in muscle fibres of cold‐acclimated mice

  2010cited by this paper
• Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance.

  2010cited by this paper
• Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo.

  2010cited by this paper
• NO modulates the molecular basis of rat interscapular brown adipose tissue thermogenesis.

  2010cited by this paper
• Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice.

  2010cited by this paper
• Antioxidative defense organization in retroperitoneal white adipose tissue during acclimation to cold - the involvement of L-arginine/NO pathway.

  2009influential reference
• l-Arginine supplementation induces glutathione synthesis in interscapular brown adipose tissue through activation of glutamate-cysteine ligase expression: The role of nitric oxide.

  2009cited by this paper
• Fuel selection in Wistar rats exposed to cold: shivering thermogenesis diverts fatty acids from re‐esterification to oxidation

  2009cited by this paper
• Regulation of NO Synthesis in Endothelial Cells

  2008cited by this paper
• Antioxidative defence alterations in skeletal muscle during prolonged acclimation to cold: role of l-arginine/NO-producing pathway

  2008cited by this paper
• Beneficial effects of L‐arginine–nitric oxide‐producing pathway in rats treated with alloxan

  2007cited by this paper
• The effects of cold acclimation and nitric oxide on antioxidative enzymes in rat pancreas.

  2007cited by this paper
• AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

  2007cited by this paper
• Skeletal Muscle Fiber-type Switching, Exercise Intolerance, and Myopathy in PGC-1α Muscle-specific Knock-out Animals*

  2007cited by this paper
• AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.

  2007cited by this paper
• Adiponectin Increases Fatty Acid Oxidation in Skeletal Muscle Cells by Sequential Activation of AMP-Activated Protein Kinase, p38 Mitogen-Activated Protein Kinase, and Peroxisome Proliferator–Activated Receptor α

  2006cited by this paper
• Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates.

  2006cited by this paper
• The effects of l-arginine and l-NAME supplementation on redox-regulation and thermogenesis in interscapular brown adipose tissue

  2005cited by this paper
• The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity.

  2004cited by this paper
• Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

  2004cited by this paper
• Fat to the fire: the regulation of lipid oxidation with exercise and environmental stress.

  2004cited by this paper
• Overexpression of endothelial nitric oxide synthase increases skeletal muscle blood flow and oxygenation in severe rat hind limb ischemia.

  2003cited by this paper
• Chronic Cold Exposure Increases Skeletal Muscle Oxidative Structure and Function in Monodelphis domestica, a Marsupial Lacking Brown Adipose Tissue

  2003cited by this paper
• Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle.

  2003cited by this paper
• Modulation of mitochondrial nitric oxide synthase and energy expenditure in rats during cold acclimation.

  2003cited by this paper
• Exercise training increases lipid metabolism gene expression in human skeletal muscle.

  2002cited by this paper
• Chronic blockade of NO synthase paradoxically increases islet NO production and modulates islet hormone release.

  2000cited by this paper
• Effect of a NOS Inhibitor, L‐NMMA, on the Contractile Function of Reperfused Skeletal Muscle

  1999cited by this paper
• Effects of nitric oxide on the contraction of skeletal muscle

  1999cited by this paper
• Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.

  1999cited by this paper
• Non-enzymatic production of nitric oxide (NO) from NO synthase inhibitors.

  1998cited by this paper
• A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.

  1998cited by this paper
• Identification, Characterization, and Tissue Distribution of Human Peroxisome Proliferator-activated Receptor (PPAR) Isoforms PPARγ2 versus PPARγ1 and Activation with Retinoid X Receptor Agonists and Antagonists*

  1997cited by this paper
• Effects of the nitric oxide synthase inhibitor N omega nitro-L-arginine methyl ester on electrical activity and ion channels of mouse pancreatic B cells.

  1996cited by this paper
• Effects of acute and chronic inhibition of nitric oxide synthase on brown adipose tissue thermogenesis.

  1996influential reference
• The insulin secretory response to intravenous glucose in the rat is independent of NO formation.

  1995cited by this paper
• Stimulatory effects of cold exposure and cold acclimation on glucose uptake in rat peripheral tissues.

  1990cited by this paper
• Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter

  1990cited by this paper
• Photoperiod and Thermoregulation in Vertebrates: Body Temperature Rhythms and Thermogenic Acclimation

  1989cited by this paper
• Molecular kinetics of beef heart lactate dehydrogenase.

  1974cited by this paper
• MECHANISMS CONTROLLING THE

  1971cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Short-term cold stress effects on antioxidant, metabolic, and immune responses in the red and white muscles of juvenile yellowfin tuna (Thunnus albacares)

  2026cites this paper
• Potential health benefits of cold-water immersion: the central role of PGC-1α.

  2025cites this paper
• Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle.

  2025cites this paper
• From molecular to physiological responses: Improved stress tolerance and longevity in Drosophila melanogaster under fluctuating thermal regimes.

  2024cites this paper
• α-Actinin-3 deficiency protects from the effects of acute cold exposure through altered skeletal muscle Ca2+ and OXPHOS signaling

  2024cites this paper
• Intermittent cold stimulation affects energy metabolism and improves stress resistance in broiler heart

  2023cites this paper
• Effect of Cold Adaptation on the State of Cardiovascular System and Cardiac Tolerance to Ischemia/Reperfusion Injury

  2023cites this paper
• l-Arginine Induces White Adipose Tissue Browning—A New Pharmaceutical Alternative to Cold

  2022cites this paper
• Energy metabolism in the pancreas of ground squirrels (Spermophilus citellus) during prolonged cold exposure and in hibernation

  2021cites this paper
• Whole‐body endothermy: ancient, homologous and widespread among the ancestors of mammals, birds and crocodylians

  2021cites this paper
• Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging

  2018cites this paper
• The Influence of Post-Exercise Cold-Water Immersion on Adaptive Responses to Exercise: A Review of the Literature

  2018cites this paper
• The Main Physiological Mechanisms of Cold Adaptation in Humans

  2018cites this paper
• A lesson from the oxidative metabolism of hibernator heart: Possible strategy for cardioprotection.

  2018cites this paper
• Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic.

  2017cites this paper
• Passive and post-exercise cold-water immersion augments PGC-1α and VEGF expression in human skeletal muscle

  2016cites this paper
• University of Birmingham Passive and post-exercise cold-water immersion augments PGC-1alpha and VEGF expression in human skeletal muscle.

  2016cites this paper
• Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture

  2016cites this paper
• Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation

  2015cites this paper