Inhibitory effect of flavonoids on 26S proteasome activity.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Agricultural and Food Chemistry

• Publication date

  2009-10-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/jf9017492PMID 19795881
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Variably modulated gating of the 26S proteasome by ATP and polyubiquitin.

  2009cited by this paper
• Dietary seaweed modifies estrogen and phytoestrogen metabolism in healthy postmenopausal women.

  2009cited by this paper
• The effects of processing and extraction conditions on content, profile, and stability of isoflavones in a soymilk system.

  2009cited by this paper
• The constituents of Anisomeles indica and their anti-inflammatory activities.

  2009cited by this paper
• Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome

  2009cited by this paper
• Natural polyphenols as proteasome modulators and their role as anti‐cancer compounds

  2008cited by this paper
• Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib.

  2008cited by this paper
• Role of ginsenoside Rd in inhibiting 26S proteasome activity.

  2008cited by this paper
• Relationship between the methylation status of dietary flavonoids and their growth‐inhibitory and apoptosis‐inducing activities in human cancer cells

  2008cited by this paper
• Glycitein activates extracellular signal-regulated kinase via vascular endothelial growth factor receptor signaling in nontumorigenic (RWPE-1) prostate epithelial cells.

  2007cited by this paper
• Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells.

  2007cited by this paper
• Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma.

  2007cited by this paper
• Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate*

  2006cited by this paper
• ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome.

  2006cited by this paper
• Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells.

  2005cited by this paper
• The development of proteasome inhibitors as anticancer drugs.

  2004cited by this paper
• The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction.

  2002cited by this paper
• Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor.

  2001cited by this paper
• Proteasome inhibitors: from research tools to drug candidates.

  2001cited by this paper
• The Sizes of Peptides Generated from Protein by Mammalian 26 and 20 S Proteasomes

  1999cited by this paper
• The chemopreventive properties of soy isoflavonoids in animal models of breast cancer

  1997cited by this paper
• Processive Degradation of Proteins and Other Catalytic Properties of the Proteasome from Thermoplasma acidophilum*

  1997cited by this paper
• Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm.

  1994cited by this paper

• Effect of the polyphenol flavonoids fisetin and quercetin on the adipogenic differentiation of human mesenchymal stromal cells

  2024cites this paper
• Flavonoid diversity and roles in the lipopolysaccharide-mediated inflammatory response of monocytes and macrophages.

  2024cites this paper
• Drug Combination Studies of Isoquinolinone AM12 with Curcumin or Quercetin: A New Combination Strategy to Synergistically Inhibit 20S Proteasome

  2024cites this paper
• Insights into physiological roles of flavonoids in plant cold acclimation

  2024cites this paper
• Advances in heterocycles as DNA intercalating cancer drugs

  2022cites this paper
• Investigation of the binding behavior of bioactive 7-methoxyflavone to human serum albumin by coupling multi-spectroscopic with computational approaches.

  2022cites this paper
• Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson’s disease models

  2020cites this paper
• Natural Exogenous Antioxidant Defense against Changes in Human Skin Fibroblast Proteome Disturbed by UVA Radiation

  2020cites this paper
• New geranyl flavonoids from the leaves of Artocarpus communis

  2018cites this paper
• Quercetin suppresses the chymotrypsin-like activity of proteasome via inhibition of MEK1/ERK1/2 signaling pathway in hepatocellular carcinoma HepG2 cells.

  2018cites this paper
• Borneol and Luteolin from Chrysanthemum morifolium Regulate Ubiquitin Signal Degradation.

  2018cites this paper
• Metabólitos secundários produzidos por fungos endofíticos isolados de Anthurium alcatrazense e Begonia spp.

  2018cites this paper
• Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms.

  2017influential citation
• Dietary Phytochemicals in Neurodegenerative Disease

  2017cites this paper
• Genetically Encodable Bacterial Flavin Transferase for Fluorogenic Protein Modification in Mammalian Cells.

  2017cites this paper
• Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradation

  2016cites this paper
• Misfolded Proteins: From Little Villains to Little Helpers in the Fight Against Cancer

  2015cites this paper
• Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome

  2015cites this paper
• Recent advances in proteasome inhibitor discovery

  2013cites this paper
• Regulation of ubiquitin and 26S proteasome mediated by phenolic compounds during oxidative stress.

  2013cites this paper
• The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors

  2013cites this paper
• Combination of quercetin and tannic acid in inhibiting 26S proteasome affects S5a and 20S expression, and accumulation of ubiquitin resulted in apoptosis in cancer chemoprevention

  2013influential citation
• Proteolytic activity in soil: A review

  2013cites this paper
• Modulation of Proteasome Pathways by Nutraceuticals

  2013cites this paper
• Pro-cellular survival and neuroprotection of citrus flavonoid: the actions of hesperetin in PC12 cells.

  2012cites this paper
• 7,3',4'-Trihydroxyisoflavone modulates multidrug resistance transporters and induces apoptosis via production of reactive oxygen species.

  2012cites this paper
• Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell.

  2012cites this paper
• A Potential Daidzein Derivative Enhances Cytotoxicity of Epirubicin on Human Colon Adenocarcinoma Caco-2 Cells

  2012cites this paper
• Naturally occurring flavonoids as inhibitors of purified cytosolic glutathione S-transferase

  2012cites this paper
• Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation

  2011cites this paper
• The electrochemical method for detecting 26S proteasome

  2011cites this paper
• Targeting proteasomes with natural occurring compounds in cancer treatment.

  2011influential citation
• 20S proteasome inhibitory activity of flavonoids isolated from Spatholobus suberectus

  2011influential citation