Hepatitis C virus NS3 protein interacts with ELKS-{delta} and ELKS-{alpha}, members of a novel protein family involved in intracellular transport and secretory pathways.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of General Virology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 16033967
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit.

  2004cited by this paper
• Hepatitis C virus NS5A protein interacts with 2',5'-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner.

  2004cited by this paper
• CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST

  2004influential reference
• Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity.

  2004cited by this paper
• Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts.

  2004cited by this paper
• Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit

  2004cited by this paper
• Suppression of Hepatitis C Virus Replicon by RNA Interference Directed against the NS3 and NS5B Regions of the Viral Genome

  2004cited by this paper
• Identification of Hepatitis C Virus (HCV) Subtype 1b Strains That Are Highly, or Only Weakly, Associated with Hepatocellular Carcinoma on the Basis of the Secondary Structure of an Amino-Terminal Portion of the HCV NS3 Protein

  2003cited by this paper
• Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

  2003cited by this paper
• Hepatocyte transformation and tumor development induced by hepatitis C virus NS3 c-terminal deleted protein.

  2003cited by this paper
• Nonstructural Protein Precursor NS4A/B from Hepatitis C Virus Alters Function and Ultrastructure of Host Secretory Apparatus

  2003cited by this paper
• Physical interaction between hepatitis C virus NS4B protein and CREB-RP/ATF6beta.

  2002cited by this paper
• Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma

  2002influential reference
• Characterization of Novel Rab6‐Interacting Proteins Involved in Endosome‐to‐TGN Transport

  2002influential reference
• Interaction between hepatitis C virus proteins and host cell factors.

  2002cited by this paper
• Correlation between Secondary Structure of an Amino‐Terminal Portion of the Nonstructural Protein 3 (NS3) of Hepatitis C Virus and Development of Hepatocellular Carcinoma

  2002cited by this paper
• A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

  2002influential reference
• Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1.

  2002cited by this paper
• The Arginine-1493 Residue in QRRGRTGR1493G Motif IV of the Hepatitis C Virus NS3 Helicase Domain Is Essential for NS3 Protein Methylation by the Protein Arginine Methyltransferase 1

  2001cited by this paper
• The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis.

  2001cited by this paper
• Cell transformation induced by hepatitis C virus NS3 serine protease

  2001cited by this paper
• Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

  2001cited by this paper
• Subcellular Localization, Stability, andtrans-Cleavage Competence of the Hepatitis C Virus NS3-NS4A Complex Expressed in Tetracycline-Regulated Cell Lines

  2000cited by this paper
• Hepatitis C--global prevalence (update).

  2000cited by this paper
• Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms.

  2000cited by this paper
• Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties.

  2000cited by this paper
• Protein Kinase C Recognizes the Protein Kinase A-binding Motif of Nonstructural Protein 3 of Hepatitis C Virus*

  1999cited by this paper
• Hepatitis C--global prevalence (update).

  1999cited by this paper
• Identification and characterization of a histone binding site of the non-structural protein 3 of hepatitis C virus.

  1999cited by this paper
• Fusion of a novel gene, ELKS, to RET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma

  1999cited by this paper
• Characterisation of non-structural protein 3 of hepatitis C virus as modulator of protein phosphorylation mediated by PKA and PKC: evidences for action on the level of substrate and enzyme

  1999cited by this paper
• Complex formation of the nonstructural protein 3 of hepatitis C virus with the p53 tumor suppressor

  1998cited by this paper
• Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization

  1997cited by this paper
• Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells

  1995cited by this paper
• Behavior of the small GTP‐binding protein rab6 in the liver of normal rats and rats presenting an acute inflammatory reaction

  1995cited by this paper
• The small GTP-binding protein rab6 functions in intra-Golgi transport

  1994cited by this paper
• Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus.

  1993cited by this paper
• Secreted placental alkaline phosphatase as a eukaryotic reporter gene.

  1992cited by this paper
• Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis.

  1991cited by this paper
• Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome.

  1989cited by this paper

• A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

  2020cites this paper
• Role of Rab GTPases in HSV-1 infection: Molecular understanding of viral maturation and egress.

  2018cites this paper
• Induction of Cell-Mediated Immune Responses in Mice by DNA Vaccines That Express Hepatitis C Virus NS3 Mutants Lacking Serine Protease and NTPase/RNA Helicase Activities

  2014influential citation
• Oral administration of genetically modified Bifidobacterium displaying HCV-NS3 multi-epitope fusion protein could induce an HCV-NS3-specific systemic immune response in mice.

  2014cites this paper
• Hepatitis C Virus Non-Structural Protein 3 Interacts with Cytosolic 5′(3′)-Deoxyribonucleotidase and Partially Inhibits Its Activity

  2013cites this paper
• Rab6 Dependent Post-Golgi Trafficking of HSV1 Envelope Proteins to Sites of Virus Envelopment

  2013cites this paper
• Hepatitis C virus intracellular host interactions

  2010cites this paper
• Isolation of Hepatitis C virus NS3 interacting proteins in the context of replication

  2010cites this paper
• Detection of the hepatitis C virus antigen in kidney tissue from infected patients with various glomerulonephritis.

  2009cites this paper
• HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters.

  2009cites this paper
• Hepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent Pathway

  2008cites this paper
• Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.

  2008cites this paper
• NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner.

  2006cites this paper
• Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis.

  2006cites this paper