Conjugated linoleic acid (CLA) and obesity

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Public Health Nutrition

• Publication date

  2007-10-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1017/S1368980007000687PMID 17903328
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Efficacy of conjugated linoleic acid for reducing fat mass : a meta-analysis in humans 1 , 2

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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation

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• Conjugated linoleic acid evokes de‐lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue

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• Conjugated Linoleic Acid Promotes Human Adipocyte Insulin Resistance through NFκB-dependent Cytokine Production*

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• Dietary protein modulates the effect of CLA on lipid metabolism in rats

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• Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans.

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• Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10,cis-12-isomer of linoleic acid.

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• Conjugated linoleic acids, atherosclerosis, and hepatic very-low-density lipoprotein metabolism.

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• Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase1 expression and enzyme activity.

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• Conjugated linoleic acid (CLA) induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines

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• Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes.

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• Conjugated linoleic acid decreases fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry

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• Inhibition of carcinogenesis by conjugated linoleic acid: potential mechanisms of action.

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• Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse DOI 10.1194/jlr.M20008-JLR200

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• Effects of dietary conjugated linoleic acid on the expression of uncoupling proteins in mice and rats

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• Dietary conjugated linoleic acid reduces body fat mass and affects gene expression of proteins regulating energy metabolism in mice.

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• Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome.

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• Dietary conjugated linoleic acids affect tissue lipid composition but not de novo lipogenesis in finishing pigs

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• Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice.

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• Conjugated linoleic acid improves feed efficiency, decreases subcutaneous fat, and improves certain aspects of meat quality in stress-genotype pigs.

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• Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat.

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• A single oral administration of conjugated linoleic acid enhanced energy metabolism in mice

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• Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor α-null mice

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• The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans

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• Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats.

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• Evaluation of conjugated linoleic acid and dietary antibiotics as growth promotants in weanling pigs.

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• Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology.

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• Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, cis-12 conjugated linoleic acid and its derivatives.

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• Conjugated linoleic acid reduces body fat mass in overweight and obese humans.

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• Changes in Body Composition with Conjugated Linoleic Acid

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• Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression.

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• Conjugated linoleic acid suppresses triglyceride accumulation and induces apoptosis in 3T3-L1 preadipocytes

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• Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.

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• The trans-10,cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes.

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• Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha.

  1999cited by this paper
• Dietary conjugated linoleic acids increase lean tissue and decrease fat deposition in growing pigs.

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• Evidence that the trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes in mice

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• Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster

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• Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse.

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• Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse.

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• Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression.

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• Effect of conjugated linoleic acid on body composition in mice

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• The effect of conjugated linoleic acid on fat to lean repartitioning and feed conversion in pigs

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• Isomers in commercial samples of conjugated linoleic acid

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• Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency.

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• Intermediates and products of the biohydrogenation of linoleic acid by Butyrinvibrio fibrisolvens.

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• The Dual Role of Conjugated Linoleic Acid in Obesity and Metabolic Disorders

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• Flavonoid-rich extracts of Nelumbo nucifera leaves alleviate obesity in HFD-fed mice via microbiota-dependent modulation of brown fat thermogenesis.

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• Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega‐7,9 trans‐fat rumenic acid

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• Body Fat Changes and Liver Safety in Obese and Overweight Women Supplemented with Conjugated Linoleic Acid: A 12-Week Randomised, Double-Blind, Placebo-Controlled Trial

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• The Human Breast Milk Metabolome in Overweight and Obese Mothers

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• Obese Mice Losing Weight Due to trans-10,cis-12 Conjugated Linoleic Acid Supplementation or Food Restriction Harbor Distinct Gut Microbiota.

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• Antioxidative effect of CLA diet and endurance training in liver and skeletal muscles of rat

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• Effect of Conjugated Linoleic Acid-enriched Butter After 24 hours of Intestinal Mucositis Induction

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• The Effect of Conjugated Linoleic Acids (CLA) Supplementation on the Activity of Enzymes Participating in the Formation of Arachidonic Acid in Liver Microsomes of Rats—Probable Mechanism of CLA Anticancer Activity

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• The phospholipase C inhibitor U73122 attenuates trans-10, cis-12 conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.

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• Equimolar mixture of c9,t11 and t9,t11 CLA inhibits the growth and induces apoptosis in Caco-2 cells

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• 10e12z CLA alters adipocyte differentiation and adipocyte cytokine expression and induces macrophage proliferation.

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• Short Communication Conjugated linoleic acid induces hepatic expression of fibroblast growth factor 21 through PPAR-a

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• Caenorhabditis elegans as a model to study the effectiveness and metabolic targets of dietary supplements used for obesity treatment: the specific case of a conjugated linoleic acid mixture (Tonalin).

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