Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2013-05-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.1300592110PMID 23674686PMCID PMC3696775
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010cited by this paper
• Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains.

  2010influential reference
• Hox genes and regional patterning of the vertebrate body plan.

  2010cited by this paper
• Axial patterning in snakes and caecilians: evidence for an alternative interpretation of the Hox code.

  2009cited by this paper
• Cross-regulatory protein–protein interactions between Hox and Pax transcription factors

  2008cited by this paper
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  2008cited by this paper
• A homeo-paired domain-binding motif directs Myf5 expression in progenitor cells of limb muscle

  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb.

  2006cited by this paper
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  2005cited by this paper
• Modulating Hox gene functions during animal body patterning

  2005cited by this paper
• Evolution of the vertebral formulae in mammals: a perspective on developmental constraints.

  2005cited by this paper
• Hox genes specify vertebral types in the presomitic mesoderm.

  2005influential reference
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  2003cited by this paper
• Hox10 and Hox11 Genes Are Required to Globally Pattern the Mammalian Skeleton

  2003cited by this paper
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  2002cited by this paper
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  2001influential reference
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  2001cited by this paper
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  2000cited by this paper
• Segmental identity can change independently in the hindbrain and rhombencephalic neural crest

  1997cited by this paper
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  1994cited by this paper
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  1986cited by this paper
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  1986cited by this paper

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