Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Controlled Release

• Publication date

  2015-06-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.jconrel.2014.12.017PMID 25523518PMCID PMC4456098
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

  2015cited by this paper
• Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo.

  2013cited by this paper
• Polymeric immunoglobulin receptor traffics through two distinct apically targeted pathways in primary lacrimal gland acinar cells

  2013cited by this paper
• Novel Strategies for Anterior Segment Ocular Drug Delivery

  2013cited by this paper
• Mycotic keratitis: epidemiology, diagnosis and management.

  2013cited by this paper
• A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.

  2013cited by this paper
• Basolateral sorting of the coxsackie and adenovirus receptor through interaction of a canonical YXXΦ motif with the clathrin adaptors AP-1A and AP-1B

  2012cited by this paper
• Emerging roles for ubiquitin in adenovirus cell entry

  2012cited by this paper
• Direct Imaging of RAB27B-Enriched Secretory Vesicle Biogenesis in Lacrimal Acinar Cells Reveals Origins on a Nascent Vesicle Budding Site

  2012cited by this paper
• The PDZ1 and PDZ3 Domains of MAGI-1 Regulate the Eight-Exon Isoform of the Coxsackievirus and Adenovirus Receptor

  2012cited by this paper
• Biodegradation of elastin‐like polypeptide nanoparticles

  2012cited by this paper
• Glaucoma.

  2011cited by this paper
• Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain.

  2011cited by this paper
• Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland.

  2011cited by this paper
• A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland

  2011cited by this paper
• Advancements in ocular drug delivery.

  2010cited by this paper
• Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia

  2010cited by this paper
• Elastin‐Like Polypeptides as a Purification Tag for Recombinant Proteins

  2010cited by this paper
• Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.

  2010cited by this paper
• Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

  2010cited by this paper
• Recent advances in ophthalmic drug delivery.

  2010cited by this paper
• Lacrimal Gland Overview

  2010cited by this paper
• Neurologic evaluation of acute lacrimomimetic effect of cyclosporine in an experimental rabbit dry eye model.

  2009cited by this paper
• Mycotic keratitis: an overview of diagnosis and therapy

  2008cited by this paper
• Direct interaction between Rab3D and the polymeric immunoglobulin receptor and trafficking through regulated secretory vesicles in lacrimal gland acinar cells.

  2008cited by this paper
• Interaction of the Coxsackie and adenovirus receptor (CAR) with the cytoskeleton: Binding to actin

  2007cited by this paper
• Elucidating the assembled structure of amphiphiles in solution via cryogenic transmission electron microscopy.

  2007cited by this paper
• Scleritis and peripheral ulcerative keratitis.

  2007cited by this paper
• Novel Fiber-Dependent Entry Mechanism for Adenovirus Serotype 5 in LacrimalAcini

  2006cited by this paper
• Evidence for Early Endosome‐like Fusion of Recently Endocytosed Synaptic Vesicles

  2006cited by this paper
• Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics.

  2006cited by this paper
• The use of mucoadhesive polymers in ocular drug delivery.

  2005cited by this paper
• Noncompliance with ocular hypotensive treatment in patients with glaucoma or ocular hypertension an evidence-based review.

  2005cited by this paper
• Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells

  2005cited by this paper
• Internalization and trafficking mechanisms of coxsackievirus B3 in HeLa cells.

  2005cited by this paper
• Biodistribution of Radioiodinated Adenovirus Fiber Protein Knob Domain after Intravenous Injection in Mice

  2004cited by this paper
• Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.

  2004cited by this paper
• Structure and Chromosomal Localization of the Murine Coxsackievirus and Adenovirus Receptor Gene

  2003cited by this paper
• Regulatory pathways in lacrimal gland epithelium.

  2003cited by this paper
• Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape.

  2002cited by this paper
• Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery.

  2002cited by this paper
• The polymeric immunoglobulin receptor translocates pneumococci across human nasopharyngeal epithelial cells.

  2000cited by this paper
• Optical and visual impact of tear break-up in human eyes.

  2000cited by this paper
• Cholinergic stimulation of lacrimal acinar cells promotes redistribution of membrane-associated kinesin and the secretory protein, beta-hexosaminidase, and increases kinesin motor activity.

  1997cited by this paper
• Na-K-ATPase in lacrimal gland acinar cell endosomal system: correcting a case of mistaken identity.

  1996cited by this paper
• Poly(ethylene oxide)-poly(propylene oxide )-poly (ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamics, structure, dynamics, and modeling

  1995cited by this paper
• Minimizing systemic absorption of topically administered ophthalmic drugs.

  1993cited by this paper
• Molecular modeling of micelle formation and solubilization in block copolymer micelles. 1. A self-consistent mean-field lattice theory.

  1993cited by this paper
• Which fluorophore is brightest? A comparison of the staining obtained using fluorescein, tetramethylrhodamine, lissamine rhodamine, texas red, and cyanine 3.18

  1992cited by this paper
• Use of collagen corneal shields in the treatment of bacterial keratitis.

  1988cited by this paper
• Evidence for a repeating cross‐beta sheet structure in the adenovirus fibre.

  1983cited by this paper

• Protective effects of combined vitamins C and PEG-E on peripheral nerves during hypothermic storage at 4 °C: histological study and oxidative stress status.

  2025cites this paper
• Consistent Intraocular Pressure Reduction by Solid Drug Nanoparticles in Fixed Combinations for Glaucoma Therapy

  2024cites this paper
• Long-Acting Hydrogel Eye Drops Composite Sequentially Releases Basic Fibroblast Growth Factor and Carbomer for Synergistic Promotion of the Repair of Corneal Epithelium

  2024cites this paper
• Anti-oxidative and mucin-compensating dual-functional nano eye drops for synergistic treatment of dry eye disease

  2022cites this paper
• Protein and polypeptide mediated delivery to the eye.

  2022cites this paper
• Elastin-like polypeptide-based micelles as a promising platform in nanomedicine.

  2022cites this paper
• Novel drug delivery systems for the management of dry eye.

  2022cites this paper
• The Role Of Nano- Ophthalmology In Treating Dry Eye Disease.

  2020cites this paper
• A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye

  2020cites this paper
• Elastin-Like Polypeptides for Biomedical Applications.

  2020cites this paper
• Nanoparticles based on natural, engineered or synthetic proteins and polypeptides for drug delivery applications.

  2020cites this paper
• Actin and Myosin in Non-Neuronal Exocytosis

  2020cites this paper
• Application of advances in endocytosis and membrane trafficking to drug delivery.

  2020cites this paper
• Recent trends in protein and peptide-based biomaterials for advanced drug delivery

  2020cites this paper
• Inverse regulation of secretion and inflammation in human airway gland serous cells by neuropeptides upregulated in allergy and asthma

  2019cites this paper
• Dry eye disease immune responses and topical therapy

  2019cites this paper
• A New Direction in Ophthalmic Development: Nanoparticle Drug Delivery Systems.

  2016cites this paper
• Safety and toxicity of nanomaterials for ocular drug delivery applications

  2016cites this paper
• Elastin-like polypeptides in drug delivery.

  2016cites this paper
• Title : Elastin-like recombinamers as smart drug delivery systems

  2015cites this paper