Drug-drug interactions and masking effects in sport doping: influence of miconazole administration on the urinary concentrations of endogenous anabolic steroids

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Forensic Toxicology

• Publication date

  2016-06-20

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s11419-016-0325-x
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• In vitro evaluation of the effects of anti-fungals, benzodiazepines and non-steroidal anti-inflammatory drugs on the glucuronidation of 19-norandrosterone: implications on doping control analysis.

  2016influential reference
• Detection of Synthetic Forms of Endogenous Anabolic Androgenic Steroids by GC-C-IRMS

  2015cited by this paper
• Masking and unmasking strategies in sport doping

  2015cited by this paper
• Drug-drug interaction and doping, part 2: an in vitro study on the effect of non-prohibited drugs on the phase I metabolic profile of stanozolol.

  2014influential reference
• Monitoring of biological markers indicative of doping: the athlete biological passport

  2014influential reference
• Drug-drug interaction and doping, part 1: an in vitro study on the effect of non-prohibited drugs on the phase I metabolic profile of toremifene.

  2014cited by this paper
• Effects of ketoconazole on the excretion kinetics of methandienone . An in vivo study

  2014cited by this paper
• Confounding factors and genetic polymorphism in the evaluation of individual steroid profiling

  2014cited by this paper
• Narrowing the gap between the number of athletes who dope and the number of athletes who are caught: scientific advances that increase the efficacy of antidoping tests

  2014cited by this paper
• Androgens and doping tests: genetic variation and pit-falls.

  2012cited by this paper
• The athlete biological passport.

  2011influential reference
• A pilot study on subject‐based comprehensive steroid profiling: novel biomarkers to detect testosterone misuse in sports

  2011cited by this paper
• Relevance of the selective oestrogen receptor modulators tamoxifen, toremifene and clomiphene in doping field: endogenous steroids urinary profile after multiple oral doses.

  2011cited by this paper
• Urine stability and steroid profile: towards a screening index of urine sample degradation for anti-doping purpose.

  2011cited by this paper
• Population based evaluation of a multi-parametric steroid profiling on administered endogenous steroids in single low dose.

  2010cited by this paper
• Detection of the misuse of steroids in doping control.

  2010cited by this paper
• Subject-based steroid profiling and the determination of novel biomarkers for DHT and DHEA misuse in sports.

  2010cited by this paper
• Reference ranges for urinary concentrations and ratios of endogenous steroids, which can be used as markers for steroid misuse, in a Caucasian population of athletes.

  2010influential reference
• Biochemical and physiological aspects of endogenous androgens.

  2010cited by this paper
• Masking and manipulation.

  2010cited by this paper
• Declared Use of Medication in Sports

  2008cited by this paper
• Published Online First

  2008cited by this paper
• Factors influencing the steroid profile in doping control analysis.

  2008cited by this paper
• Validation of an extended method for the detection of the misuse of endogenous steroids in sports, including new hydroxylated metabolites.

  2008cited by this paper
• From population- to subject-based limits of T/E ratio to detect testosterone abuse in elite sports.

  2008cited by this paper
• Bayesian detection of abnormal values in longitudinal biomarkers with an application to T/E ratio.

  2007cited by this paper
• Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite

  2007cited by this paper
• The Use of Dietary Supplements and Medications by Canadian Athletes at the Atlanta and Sydney Olympic Games

  2006cited by this paper
• Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism.

  2006cited by this paper
• Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes.

  2005cited by this paper
• Effect of antifungal drugs on cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 activities in human liver microsomes.

  2005cited by this paper
• Medication Use in Athletes Selected for Doping Control at the Sydney Olympics (2000)

  2003cited by this paper
• The appearance of urinary 19-norandrosterone during pregnancy

  2002cited by this paper
• Human cytochrome P450 (CYP) enzymes in doping control: metabolism, interactions, adverse effects

  1996cited by this paper
• Establishing a ketoconazole suppression test for verifying testosterone administration in the doping control of athletes.

  1994cited by this paper
• Potential use of ketoconazole in a dynamic endocrine test to differentiate between biological outliers and testosterone use by athletes.

  1993cited by this paper
• Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man.

  1992influential reference
• Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.

  1987cited by this paper
• Inhibition of testicular 17α-hydroxylase and 17,20-lyase but not 3β-hydroxysteroid dehydrogenase-isomerase or 17β-hydroxysteroid oxidoreductase by ketoconazole and other imidazole drugs

  1987cited by this paper
• Mechanism of Inhibition of Human Testicular Steroidogenesis by Oral Ketoconazole

  1987cited by this paper
• Ketoconazole and other imidazole derivatives as inhibitors of steroidogenesis.

  1986cited by this paper
• Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes.

  1983cited by this paper

• Adulteration of Sports Supplements with Anabolic Steroids—From Innocent Athlete to Vicious Cheater

  2025cites this paper
• Application of the transient matrix effect for determination of anabolic–androgenic steroids in biological samples by GC–MS/MS

  2025cites this paper
• Changes in Plasma Metabolic Signature upon Acute and Chronic Morphine Administration in Morphine-Tolerant Mice

  2023cites this paper
• Development and validation of a productive liquid chromatography-tandem mass spectrometry method for the analysis of androgens, estrogens, glucocorticoids and progestagens in human serum

  2021cites this paper
• Influence of synthetic isoflavones on selected urinary steroid biomarkers: relevance to doping control.

  2021cites this paper
• Effects of the administration of miconazole by different routes on the biomarkers of the “steroidal module” of the Athlete Biological Passport

  2021cites this paper
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  2020cites this paper
• UPLC-MS-Based Procedures to Detect Prolyl-hydroxylase Inhibitors of HIF in Urine.

  2020cites this paper
• Detection of 5α-reductase inhibitors by UPLC-MS/MS: Application to the definition of the excretion profile of dutasteride in urine.

  2019cites this paper
• Detection of urinary metabolites of arimistane in humans by gas chromatography coupled to high accuracy mass spectrometry for antidoping analyses.

  2019cites this paper
• An investigation on the metabolic pathways of synthetic isoflavones by gas chromatography coupled to high accuracy mass spectrometry.

  2019cites this paper
• Drug-drug interaction and doping: Effect of non-prohibited drugs on the urinary excretion profile of methandienone.

  2018cites this paper
• Non-targeted LC-MS based metabolomics analysis of the urinary steroidal profile.

  2017cites this paper
• Characterization of the phase I and phase II metabolic profile of tolvaptan by in vitro studies and liquid chromatography–mass spectrometry profiling: Relevance to doping control analysis

  2017cites this paper