A mechanistically guided design leads to the synthesis of an efficient and practical new reagent for the highly enantioselective, catalytic dihydroxylation of olefins.

[structure: see text] The catalytic asymmetric dihydroxylation of olefins has been accomplished with high enantioselectivities using a proline-based catalyst. The pre-transition-state assembly for styrene is shown.

• Publication year

  2003

• Venue

  Organic Letters

• Publication date

  2003-08-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/OL035192SPMID 12967298
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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