Are cardiac G-proteins altered in rat models of hypertension?

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Hypertension

• Publication date

  1993-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00004872-199304000-00005PMID 8390502
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Guanine nucleotide regulatory proteins in the spontaneously hypertensive rat.

  1993cited by this paper
• Adrenergic receptors and their signal transduction mechanisms in hypertension.

  1992cited by this paper
• Desensitization of adenylate cyclase and increase of Gi alpha in cardiac hypertrophy due to acquired hypertension.

  1992cited by this paper
• Cardiac alpha 1-adrenoceptors mediate positive inotropy via myofibrillar sensitization.

  1992cited by this paper
• Enhanced myocardial adenylate cyclase activity in spontaneously hypertensive rats.

  1992cited by this paper
• On the role of renal alpha-adrenergic receptors in spontaneously hypertensive rats.

  1992cited by this paper
• Role of altered G-protein expression in the regulation of myocardial adenylate cyclase activity and force of contraction in spontaneous hypertensive cardiomyopathy in rats

  1992cited by this paper
• Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.

  1991cited by this paper
• Beta 1- and beta 2-adrenoceptors in the human heart: properties, function, and alterations in chronic heart failure.

  1991cited by this paper
• ENHANCED BETA‐ADRENERGIC SIGNAL TRANSDUCTION IN SPONTANEOUSLY HYPERTENSIVE RATS

  1991cited by this paper
• Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi alpha) in spontaneously hypertensive rats.

  1991cited by this paper
• Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

  1991cited by this paper
• Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins.

  1991cited by this paper
• Peripheral adrenergic receptors in hypertension.

  1990cited by this paper
• Autonomic receptor interactions in isolated cardiac myocytes from hypertensive rats.

  1989cited by this paper
• Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranes.

  1989cited by this paper
• Alpha and beta-adrenoceptors in hypertension. I. Cardiac and renal alpha 1-, beta 1-, and beta 2-adrenoceptors in rat models of acquired hypertension.

  1989cited by this paper
• Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats

  1988cited by this paper
• Impaired cardiac muscarinic receptor function in dogs with heart failure.

  1988cited by this paper
• G proteins and cardiovascular disease.

  1988cited by this paper
• Altered responsiveness of adenylate cyclase to adenosine and other agents in the myocardial sarcolemma and aorta of spontaneously-hypertensive rats.

  1988cited by this paper
• Increased Inositol Monophosphate Production in Cardiovascular Tissues of DOCA‐Salt Hypertensive Rats

  1988cited by this paper
• Beta-adrenergic receptor alterations in hypertension--physiological and molecular correlates.

  1987cited by this paper
• Increased beta 2-adrenoreceptor density in heart, kidney and lung of spontaneously hypertensive rats.

  1987cited by this paper
• G proteins: transducers of receptor-generated signals.

  1987cited by this paper
• Reduction in the activity of the stimulatory guanine nucleotide-binding protein in the myocardium of spontaneously hypertensive rats.

  1987cited by this paper
• Alterations of the Glomerular β-Adrenoceptor-Linked Adenylate Cyclase System in Perinephritis Hypertension

  1986cited by this paper
• Increased sensitivity to alpha-adrenoceptor stimulation but intact purinergic and muscarinergic effects in prehypertensive cardiac hypertrophy of spontaneously hypertensive rats.

  1986cited by this paper
• A review of changes in vascular smooth muscle functions in hypertension: isolated tissue versus in vivo studies.

  1985cited by this paper
• Reduced levels of cardiac cAMP-dependent protein kinase in spontaneously hypertensive rat.

  1985cited by this paper
• The Cardiac and Brain Micro vessel Adenylate Cyclase System in Deoxycorticosterone Acetate‐Hypertensive Rats

  1984cited by this paper
• Reversal of Changes in Myocardial β‐Receptors and Inotropic Responsiveness with Regression of Cardiac Hypertrophy in Renal Hypertensive Rats (RHR)

  1984cited by this paper
• Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension.

  1984cited by this paper
• Altered hormone sensitivity of adenylate cyclase in myocardial sarcolemma of renal hypertensive rats.

  1983cited by this paper
• The adenylate cyclase activity in heart membranes from normotensive and spontaneously hypertensive rats, after chemical sympathectomy, suggests the presence of presynaptic secretin receptors.

  1983cited by this paper
• Myocardial adrenergic receptors and adenylate cyclase in the developing spontaneously hypertensive rat.

  1982cited by this paper
• "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

  1981cited by this paper
• Comparative effects of alpha-methyldopa, propranolol and hydralazine therapy on cardiac adenylate cyclase activity in normal and spontaneously hypertensive rats.

  1981cited by this paper
• Age-dependent changes in the myocardial adenylate cyclase of normotensive and spontaneously hypertensive rat.

  1981cited by this paper
• Comparison of beta-adrenergic receptors and the adenylate cyclase system with muscarinic receptors and guanylate cyclase activities in the heart of spontaneously hypertensive rats.

  1981cited by this paper
• Ontogenetic development of isoproterenol subsensitivity of myocardial adenylate cyclase and beta-adrenergic receptors in spontaneously hypertensive rats.

  1980cited by this paper
• Alterations in myocardial adenylate cyclase in spontaneously hypertensive rats.

  1979cited by this paper
• Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

  1979cited by this paper
• Decreased cardiac beta-adrenergic receptors in deoxycorticosterone-salt and renal hypertensive rats.

  1979cited by this paper
• Adrenergic reactivity of the myocardium in hypertension.

  1978cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Aberrations of cyclic nucleotide metabolism in the hearts and vessels of hypertensive rats.

  1974cited by this paper

• Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment

  2019cites this paper
• The Hypertrophied Heart

  2012influential citation
• Renal G proteins in male and female rats Ontogenesis of sympathetic responsiveness in spontaneously hypertensive rats. II.

  2011cites this paper
• Hydrogen peroxide enhances the expression and function of Giα proteins in aortic vascular smooth muscle cells from Sprague-Dawley rats : role of growth factor receptors transactivation

  2011cites this paper
• CHANGES IN THE IN VITRO PHARMACODYNAMIC PROPERTIES OF METOPROLOL IN ATRIA ISOLATED FROM SPONTANEOUSLY HYPERTENSIVE RATS

  2007cites this paper
• DIABETES AND NATRIURETIC SUBSTANCES

  2006cites this paper
• DIABETES AND NATRIURETIC SUBSTANCES Éva Ruzicska

  2004cites this paper
• Propiedades farmacodinámicas in vitro de los bloqueantes B adrenérgicos propranolol y atenolol en ratas con coartación aórtica

  2003cites this paper
• In vivo and in vitro pharmacodynamic properties of metoprolol in aortic coarctated rats.

  2003cites this paper
• Effect of beta-adrenoceptor antagonist and angiotensin-converting enzyme inhibitor on hypertension-associated changes in adenylyl cyclase type V messenger RNA expression in spontaneously hypertensive rats.

  2003cites this paper
• Effect of &bgr;-Adrenoceptor Antagonist and Angiotensin-converting Enzyme Inhibitor on Hypertension-associated Changes in Adenylyl Cyclase Type V Messenger RNA Expression in Spontaneously Hypertensive Rats

  2003cites this paper
• Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation

  2001cites this paper
• Enhanced expression of Gi proteins in non‐hypertrophic hearts from rats with hypertension‐induced by L‐NAME treatment

  2000cites this paper
• Role of G Proteins in Hypertension and Hypertrophy

  2000cites this paper
• Volume overload cardiac hypertrophy exhibits decreased expression of Gsα and not of Giα in heart

  2000cites this paper
• Alterations in G-Proteins and β-Adrenergic Responsive Adenylyl Cyclase in Rat Urinary Bladder during Aging

  2000cites this paper
• Heterotrimeric G proteins in heart disease 1

  2000cites this paper
• The cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in monocrotaline-treated rats.

  2000cites this paper
• Volume overload cardiac hypertrophy exhibits decreased expression of g(s)alpha and not of g(i)alpha in heart.

  2000cites this paper
• Heterotrimeric G proteins in heart disease.

  2000cites this paper
• G-proteins in kidneys of spontaneously hypertensive rats.

  2000cites this paper
• Properties of the ventricular adrenergic signal transduction system during ontogeny of spontaneous hypertension in rats.

  2000cites this paper
• PERTUSSIS TOXIN‐SENSITIVE G‐PROTEINS AND REGULATION OF BLOOD PRESSURE IN THE SPONTANEOUSLY HYPERTENSIVE RAT

  1999cites this paper
• Transition from Hypertrophy to Failure—Β-Adrenergic Desensitization of the Heart

  1999cites this paper
• Gelatinase A expression in endothelial cells is regulated by at least two cis-acting promoter elements.

  1999cites this paper
• Ontogenetic aspects of hypertension development: analysis in the rat.

  1999cites this paper
• Endothelin receptors in the failing and nonfailing human heart.

  1998cites this paper
• Beta-andrenoceptors in the hearts of diabetic-hypertensive rats: radioligand binding and functional experiments.

  1997cites this paper
• G protein mRNA expression in renal microvessels from spontaneously hypertensive and Wistar-Kyoto rats.

  1997cites this paper
• Enhanced expression of Gi-protein precedes the development of blood pressure in spontaneously hypertensive rats.

  1997cites this paper
• G protein mRNA expression in renal microvessels from spontaneously hypertensive and Wistar-Kyoto rats.

  1997influential citation
• Effects of renin-angiotensin blockade on sympathetic reactivity and beta-adrenergic pathway in the spontaneously hypertensive rat.

  1997cites this paper
• G-protein activation by chemokines.

  1997cites this paper
• The cardiac beta-adrenoceptor-mediated signaling pathway and its alterations in hypertensive heart disease.

  1997cites this paper
• The Cardiac β-Adrenoceptor–Mediated Signaling Pathway and Its Alterations in Hypertensive Heart Disease

  1997cites this paper
• Use of the operational model of agonism and [3H]prazosin binding to assess altered responsiveness of α1-adrenoceptors in the vas deferens of spontaneously hypertensive rat

  1997cites this paper
• Chronic treatment with carbachol sensitizes the myocardium to cAMP-induced arrhythmia.

  1996cites this paper
• Increased expression of inhibitory guanine nucleotide binding proteins in membranes from renal proximal tubules, but not brain striata, of the normotensive and the spontaneously hypertensive rat

  1996cites this paper
• Use of elastase as an internal standard in immunoblotting techniques.

  1996cites this paper
• Bradykinin and protein kinase C activation fail to stimulate renal sensory neurons in hypertensive rats.

  1996cites this paper
• Developmental regulation of the alpha-subunit of Gq/G11 as determined by quantitative immunoblot analysis.

  1995cites this paper
• Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes.

  1995cites this paper
• GTP-binding proteins 1: heterotrimeric G proteins.

  1995cites this paper
• Treatment in hypertensive cardiac hypertrophy, I. Neuropeptide Y and beta-adrenoceptors.

  1995cites this paper
• Nitric oxide regulation of ADP-ribosylation of G proteins in hypertension.

  1995cites this paper
• G protein alterations in hypertension and aging.

  1995cites this paper
• Adrenoceptors in SHR: alterations in binding characteristics and intracellular signal transduction pathways.

  1995cites this paper
• Treatment in hypertensive cardiac hypertrophy, II. Postreceptor events.

  1995cites this paper
• Ischemic preconditioning, adenosine and bethanechol protect spontaneously hypertensive isolated rat hearts.

  1995cites this paper
• Regulation of NPY/NPY Y1 receptor/G protein system in rat brain cortex.

  1995cites this paper
• Mechanisms of the circadian regulation of beta-adrenoceptor density and adenylyl cyclase activity in cardiac tissue from normotensive and spontaneously hypertensive rats.

  1995cites this paper
• GTP-binding proteins. 1: heterotrimeric G proteins.

  1994cites this paper
• Intracellular signal transduction for vasoactive peptides in hypertension.

  1994cites this paper
• Sensitization by dexamethasone of lymphocyte cyclic AMP formation: evidence for increased function of the adenylyl cyclase catalyst

  1994cites this paper
• Ontogenesis of sympathetic responsiveness in spontaneously hypertensive rats. II. Renal G proteins in male and female rats.

  1994cites this paper
• Angiotensin II/prostaglandin I2 interactions in spontaneously hypertensive rats.

  1993cites this paper