Reduced 293T cell susceptibility to acrolein due to aldose reductase-like-1 protein expression.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Toxicological Sciences

• Publication date

  2007-06-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/TOXSCI/KFM033PMID 17329238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Clonogenic cell survival assay.

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• The molecular effects of acrolein.

  2000influential reference
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  1999cited by this paper
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  1999cited by this paper
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  1985cited by this paper
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  1985cited by this paper
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  1982cited by this paper

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