Prostaglandin D2-loaded microspheres effectively activate macrophage effector functions.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  European Journal of Pharmaceutical Sciences

• Publication date

  2015-10-12

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.ejps.2015.07.001PMID 26143263
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007influential reference
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  1998cited by this paper
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  1998cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
• Biodegradable microspheres as a vaccine delivery system.

  1991cited by this paper
• Effect of the size and surface charge of polymer microspheres on their phagocytosis by macrophage.

  1988cited by this paper

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