SCIENCE@home

Detection and typing of human papilloma virus in the oral mucosa of patients infected with human immunodeficiency virus

K. Shetty,A. Chattopadhyay,J. Leigh

Published 2005 in Oral Oncology Extra

ABSTRACT

Summary Recent studies have shown an increased risk of oral warts in HIV+ individuals despite treatment with highly active antiretroviral therapy (HAART). Human papilloma virus (HPV) infection has attracted a great deal of attention, not just because of the difficulty of managing oral warts but also because of the oncogenic potential of certain strains, in particular HPV-16 and -18, which have been detected in 20–30% of oral squamous cell carcinomas. Between 1999 and 2004, DNA extraction was performed using a multiplex PCR reaction to detect and type HPV in 12 HIV-positive adult with a clinicopathologic diagnosis of Oral Warts. HPV was detected in 11 of the 12 orals warts. HPV-32 was present in all subjects, whereas only one subject had a co-infection of HPV-32 and -7. Future studies should examine the specific roles of these specific HPV types and whether a potential link exists for oral premalignant lesions.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-28 of 28 references · Page 1 of 1

CITED BY