Regression of rat mammary tumors effected by a gonadoliberin analog.

No abstract is available for this paper.

• Publication year

  1976

• Venue

  Cancer Research

• Publication date

  1976-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 782692
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biochemical nomenclature

  1978cited by this paper
• Delay of puberty and inhibition of reproductive processes in the rat by a gonadotropin-releasing hormone agonist analog.

  1976cited by this paper
• Inhibitors of the luteinizing hormone-releasing hormone based upon modifications in the 2, 3, and 6 positions.

  1976cited by this paper
• NOMENCLATURE OF PEPTIDE HORMONES

  1976cited by this paper
• Ovulation and Gonadotropin-Releasing Activity of [d-LEU6, DES-GLY NH2 10, PRO-ETHYLAMIDE9] -GNRH

  1975cited by this paper
• Effect of the antiestrogen C1628 on the growth of rat mammary tumors.

  1974cited by this paper
• (D-Ala 6, Des-Gly-NH 2 10)-LH-RH-ethylamide: a new analogue with unusually high LH-RH-FSH-RH activity.

  1974cited by this paper
• Synthetic analogs of luteinizing hormone releasing hormone (LH-RH) substituted in position 6 and 10.

  1974cited by this paper
• Estrogen receptors in human breast cancer.

  1973cited by this paper
• The Response of Experimentally Induced Mammary Tumours in Rats to Hypophysectomy and to Pituitary Stalk Section

  1963cited by this paper
• The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons.

  1962cited by this paper
• Mammary Cancer Induced by a Single Feeding of Polynuclear Hydrocarbons, and its Suppression

  1961cited by this paper
• RAPID INDUCTION OF MAMMARY CARCINOMA IN THE RAT AND THE INFLUENCE OF HORMONES ON THE TUMORS

  1959cited by this paper

• Targeting Oestrogen Receptor Signalling in Breast Cancer Therapy.

  2025cites this paper
• Targeting luteinizing hormone‐releasing hormone: A potential therapeutics to treat gynecological and other cancers

  2018cites this paper
• Efficacy Evaluation of a Leuprorelin Formulation (Lorelin Depot Injection ® ) by Determination of Serum Testosterone in Rats

  2009cites this paper
• Leuprolide acetate: a drug of diverse clinical applications

  2007cites this paper
• Anti-tumor and endocrine effects of chronic LHRH agonist treatment (Buserelin) with or without tamoxifen in premenopausal metastatic breast cancer

  2005cites this paper
• Treatment of experimental DMBA induced mammary carcinoma with Cetrorelix (SB-75): a potent antagonist of luteinizing hormone-releasing hormone

  2005cites this paper
• Prevention of DMBA-induced rat mammary carcinomas comparing leuprolide, oophorectomy, and tamoxifen

  2004cites this paper
• Sex Hormone Dependency of Diethylnitrosamine‐induced Liver Tumors in Mice and Chemoprevention by Leuprorelin

  2001cites this paper
• The role of LH-RH analogues in the adjuvant and palliative treatment of breast cancer.

  2000cites this paper
• Combined treatment with buserelin and tamoxifen in premenopausal metastatic breast cancer: a randomized study.

  2000cites this paper
• Prevention of rat mammary carcinoma utilizing leuprolide as an equivalent to oophorectomy

  1999cites this paper
• Endocrinology of Breast Cancer

  1999cites this paper
• Cell cycle arrest in endometrial carcinoma cells exposed to gonadotropin-releasing hormone analog.

  1999cites this paper
• LHRH Superagonists and Antagonists in the Treatment of Breast Cancer

  1999cites this paper
• Endocrine therapy in metastatic breast cancer.

  1998cites this paper
• One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate.

  1997cites this paper
• Mechanisms of action of endocrine treatment in breast cancer.

  1995cites this paper
• Biodegradable microspheres in drug delivery.

  1995cites this paper
• The use of luteinizing hormone releasing hormone agonists and antagonists in gynaecological cancers.

  1994cites this paper
• The Use of GnRH Agonists in Breast and Gynecologic Cancers

  1993cites this paper
• Treatment of Duct Carcinoma of the Pancreas with the LH‐RH Analogue Buserelin

  1992cites this paper
• Peptides in Oncology I

  1992cites this paper
• GnRH analogs in gynecological oncology: a review.

  1992cites this paper
• A biodegradable delivery system for peptides: preclinical experience with the gonadotrophin-releasing hormone agonist Zoladex☆

  1992cites this paper
• LH-RH agonists in the treatment of metastatic breast cancer: ten years' experience.

  1992cites this paper
• Inhibition of growth of MCF-7 MIII human breast carcinoma in nude mice by treatment with agonists or antagonists of LH-RH

  1992cites this paper
• [Once-a-month injectable microcapsules of leuprorelin acetate].

  1991cites this paper
• Endocrine treatment of breast cancer in women.

  1990cites this paper
• Direct inhibiting effects of [D-Trp6]gonadotropin-releasing hormone on the estrogen-sensitive progression of polyoma virus-induced mammary tumors in athymic mice.

  1990cites this paper
• New endocrine approaches to breast cancer.

  1990cites this paper
• Endocrine and clinical aspects of new compounds for treatment of hormone-related cancer in gynecology.

  1990cites this paper
• Histological studies on the therapeutic effect of sustained-release microspheres of a potent LHRH agonist (leuprorelin acetate) in an experimental endometriosis model in rats.

  1990cites this paper
• Endocrine treatment of prostate cancer.

  1989cites this paper
• Leuprolide acetate in the treatment of refractory or persistent epithelial ovarian cancer.

  1989cites this paper
• Endogenous Factors Affecting the Progression of Carcinogen-Induced Rat Mammary Carcinomas

  1989cites this paper
• Therapy in premenopausal women with advanced, oestrogen positive or/and progesterone positive breast cancer: surgical oophorectomy versus the LHRH analogue, Zoladex.

  1989cites this paper
• LH-RH antagonists: design and synthesis of a novel series of peptidomimetics.

  1989cites this paper
• Metabolism of steroid-modifying anticancer agents.

  1988cites this paper
• Preclinical studies and antitumor mechanism of action of LHRH analogues.

  1988cites this paper
• [Gonadotropin-releasing hormone receptors in human breast cancer tissue].

  1988cites this paper
• Treatment of Hormone‐Dependent Cancer with Analogues of Hypothalamic Hormones. Experimental and Clinical Studies a

  1987cites this paper
• Effect of ovariectomy, hypophysectomy and/or GnRH analog (HRF) administration on the cell proliferation of the MXT mouse hormone-dependent mammary tumor.

  1987cites this paper
• Self injury and mental handicap.

  1987cites this paper
• Gonadotrophin hormone releasing analogues open new doors in cancer treatment.

  1987cites this paper
• Single-dose pharmacokinetics of leuprolide in humans following intravenous and subcutaneous administration.

  1986cites this paper
• Hormone dependence and independence of mammary tumors in mice.

  1986cites this paper
• Treatment of breast cancer with gonadotropin-releasing hormone.

  1986cites this paper
• Non-pituitary actions of hypothalamic hormones. Functional significance and therapeutic implications. General introduction.

  1986cites this paper
• Comparison of the potential for therapeutic utilities with gonadotropin-releasing hormone agonists and antagonists.

  1986cites this paper
• Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.

  1985cites this paper
• Medical castration produced by the GnRH analogue leuprolide to treat metastatic breast cancer.

  1985cites this paper
• Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist

  1985cites this paper
• Potential use of analogs of luteinizing hormone-releasing hormones in the treatment of hormone-sensitive neoplasms.

  1984cites this paper
• 15 Antisteroidal actions of LH R H agonists

  1984cites this paper
• Antitumor Effects of Analogs of Hypothalamic Hormones in Endocrine-Dependent Cancers

  1984cites this paper
• LHRH and Its Analogs

  1984cites this paper
• LHRH analogs for human mammary carcinoma

  1984cites this paper
• Vaginal absorption of a potent luteinizing hormone-releasing hormone analogue (leuprolide) in rats. IV: Evaluation of the vaginal absorption and gonadotropin responses by radioimmunoassay.

  1984cites this paper
• Long-term LHRH-agonist treatment in metastatic breast cancer as a single treatment and in combination with other additive endocrine treatments

  1984cites this paper
• Inhibition of the growth of some hormone dependent tumors byd-Trp6-LH-RH

  1984cites this paper
• LHRH-agonist treatment in metastatic prostate carcinoma.

  1984cites this paper
• Antisteroidal actions of LHRH agonists

  1984cites this paper
• Desensitization of gonadotropin-releasing response following vaginal consecutive administration of leuprolide in rats.

  1983cites this paper
• Therapeutic potential of the LHRH agonist, ICI 118630, in the treatment of advanced prostatic carcinoma.

  1983cites this paper
• Regression of rat mammary tumors by a potent luteinizing hormone-releasing hormone analogue (leuprolide) administered vaginally.

  1983influential citation
• Inhibition of mammary tumor growth in rats and mice by administration of agonistic and antagonistic analogs of luteinizing hormone-releasing hormone.

  1983cites this paper
• Inhibition of growth of a prolactin-secreting pituitary tumor in rats by analogs of luteinizing hormone-releasing hormone and somatostatin.

  1983cites this paper
• GnRH in the spinal subarachnoid space potentiates lordosis behavior in the female rat.

  1983cites this paper
• Inhibition of growth of the transplantable rat chondrosarcoma by analogs of hypothalamic hormones.

  1983cites this paper
• CLINICAL APPLICATIONS OF LHRH AND ITS ANALOGUES

  1983cites this paper
• Relation of the Neuroendocrine System to the Development of Mammary Tumors in Rats during Aging

  1983cites this paper
• Vaginal absorption of a potent luteinizing hormone-releasing hormone analog (leuprolide) in rats I: absorption by various routes and absorption enhancement.

  1982cites this paper
• Treatment with a luteinising-hormone-releasing-hormone analogue (buserelin) in premenopausal patients with metastatic breast cancer.

  1982cites this paper
• Tumor growth inhibition in patients with prostatic carcinoma treated with luteinizing hormone-releasing hormone agonists.

  1982cites this paper
• Enhanced and reversed growth in vitro of a pregnancy-dependent mouse mammary tumor (TPDMT-4) by a gonadotropin-releasing hormone agonist analog.

  1982cites this paper
• Prolactin and Prolactin Receptors in Tumor Development, Growth and Cellular Functions

  1982cites this paper
• From contraception to cancer: a review of the therapeutic applications of LHRH analogues as antitumor agents.

  1982cites this paper
• Control of Proclactin Secretion

  1982cites this paper
• Use of analogues of luteinizing hormone-releasing hormone for the treatment of cancer.

  1982cites this paper
• [Antiestrogens in the treatment of breast cancer].

  1981cites this paper
• Inhibition of the action of sex steroids by gonadotropin-releasing hormone (GnRH) agonists: a new biological effect.

  1981cites this paper
• Extrapituitary actions of gonadotropin-releasing hormone.

  1981cites this paper
• Antifertility Effects of LH-RH and Its Agonists

  1981cites this paper
• Effect of an LHRH analog on growth and hormone receptor levels in DMBA-induced mammary tumors in the rat.

  1981cites this paper
• Inhibition of prostate tumor growth in two rat models by chronic administration of D-Trp6 analogue of luteinizing hormone-releasing hormone.

  1981cites this paper
• Effects of a luteinizing hormone-releasing hormone analog and tamoxifen on the growth of an estrogen-induced prolactin-secreting rat pituitary tumor and its influence on pituitary gonadotropins.

  1981cites this paper
• Prolactin

  1981cites this paper
• A radioimmunoassay for a highly active luteinizing hormone-releasing hormone analogue and relation between the serum level of the analogue and that of gonadotropin.

  1980cites this paper
• Effects of progesterone on normal and preneoplastic mammary development in mice in relation to prolactin and estrogen.

  1980cites this paper
• Inhibition of mammary carcinogenesis of dimethylbenzanthracene treated rats with a brominated triphenylethylene.

  1979cites this paper
• Modification of the effect of a gonadoliberin analog on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by hormone replacement.

  1979influential citation
• Ovarian Growth and Uptake of lodinated D-Leu6, des Gly NH2 10-LHRH Ethylamide in HCG Treated Rats 1 2

  1979cites this paper
• Inhibition of preovulatory gonadotropin secretion and stimulation of prolactin secretion by 7,12-dimethylbenz(a)anthracene in Sprague-Dawley rats.

  1979cites this paper
• Potent agonist and antagonist analogues of luliberin containing an azaglycine residue in position 10.

  1978cites this paper
• Pituitary gonadotropin inhibition by a highly active analog of luteinizing hormone-releasing hormone.

  1978cites this paper
• Synthesis and biological activity of highly active alpha-aza analogues of luliberin.

  1978cites this paper
• Effects of a gonadotropin-releasing hormone (GnRH) analogue (A-43818) on 7, 12- dimethylbenz (a)anthracene-induced rat mammary tumors. Histological and endocrine studies.

  1977cites this paper