Treatment of neurodegenerative diseases with using of stem cells/scaffolds

S. Ghorbani,H. Eyni

Published 2016 in MOJ Anatomy & Physiology

ABSTRACT

Over the two decades, stem cell technologies have become an increasingly attractive option to treat neurodegenerative diseases. However, this approach has been limited due to transplanted cell death because of the unsuitable microenvironment. Tissue engineering by using of stem cells, scaffolds and growth factors comes to improve the chance of regeneration. In the current mini-review, we discuss the advantages of synthetic extra cellular matrix for stem cell-based therapies in patients suffering from neurodegenerative diseases. Hence, explained about biological and mechanical properties of scaffolds in nerve engineered tissues. There is growing public hope with a greater understanding of the capacity of stem cell technologies that regenerative medicine will continue to progress into effective treatments for neurodegenerative diseases.

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