Antibody Tracking Demonstrates Cell Type-Specific and Ligand-Independent Internalization of Guanylyl Cyclase A and Natriuretic Peptide Receptor C

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Molecular Pharmacology

• Publication date

  2011-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1124/mol.110.070573PMID 21498657PMCID PMC5180442
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.

  2011cited by this paper
• Prolonged atrial natriuretic peptide exposure stimulates guanylyl cyclase-a degradation.

  2010influential reference
• Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications.

  2009cited by this paper
• A Familial Mutation Renders Atrial Natriuretic Peptide Resistant to Proteolytic Degradation*

  2009influential reference
• Renal hyporesponsiveness to atrial natriuretic peptide in congestive heart failure results from reduced atrial natriuretic peptide receptor concentrations.

  2007cited by this paper
• Differential regulation of membrane guanylyl cyclases in congestive heart failure: natriuretic peptide receptor (NPR)-B, Not NPR-A, is the predominant natriuretic peptide receptor in the failing heart.

  2007cited by this paper
• Down-Regulation Does Not Mediate Natriuretic Peptide-Dependent Desensitization of Natriuretic Peptide Receptor (NPR)-A or NPR-B: Guanylyl Cyclase-Linked Natriuretic Peptide Receptors Do Not Internalize

  2005influential reference
• Calcium-dependent Dephosphorylation Mediates the Hyperosmotic and Lysophosphatidic Acid-dependent Inhibition of Natriuretic Peptide Receptor-B/Guanylyl Cyclase-B*

  2004cited by this paper
• Receptor downregulation and multivesicular-body sorting

  2002cited by this paper
• The Atrial Natriuretic Peptide Receptor (NPR-A/GC-A) Is Dephosphorylated by Distinct Microcystin-sensitive and Magnesium-dependent Protein Phosphatases*

  2002influential reference
• Ligand-regulated Internalization, Trafficking, and Down-regulation of Guanylyl Cyclase/Atrial Natriuretic Peptide Receptor-A in Human Embryonic Kidney 293 Cells*

  2002cited by this paper
• Molecular and Cellular Physiology of the Dissociation of Atrial Natriuretic Peptide from Guanylyl Cyclase A Receptors*

  2001cited by this paper
• Dynamics of internalization and sequestration of guanylyl cyclase/atrial natriuretic peptide receptor-A.

  2001cited by this paper
• Dynamin:Gtp Controls the Formation of Constricted Coated Pits, the Rate Limiting Step in Clathrin-Mediated Endocytosis

  2000cited by this paper
• The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.

  1999cited by this paper
• Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3).

  1999cited by this paper
• A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.

  1999influential reference
• Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A.

  1997cited by this paper
• Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis

  1996cited by this paper
• Interaction of Atrial Natriuretic Peptide with Its Receptors in Bovine Lung Membranes (*)

  1995cited by this paper
• Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide

  1995cited by this paper
• Dynamics of atrial natriuretic factor-guanylate cyclase receptors and receptor-ligand complexes in cultured glomerular mesangial and renomedullary interstitial cells.

  1992cited by this paper
• Kinetic analysis of internalization, recycling and redistribution of atrial natriuretic factor-receptor complex in cultured vascular smooth-muscle cells. Ligand-dependent receptor down-regulation.

  1992cited by this paper
• Differential internalization and processing of atrial-natriuretic-factor B and C receptor in PC12 cells.

  1991cited by this paper
• Cellular mechanisms of the clearance function of type C receptors of atrial natriuretic factor.

  1990influential reference
• HeLa cells contain the atrial natriuretic peptide receptor with guanylate cyclase activity.

  1989influential reference
• Identification of multiple binding sites for atrial natriuretic factor by affinity cross-linking in cultured endothelial cells.

  1986cited by this paper

• Guanylyl cyclase/natriuretic peptide receptor-A: Identification, molecular characterization, and physiological genomics

  2023cites this paper
• Discovery of another mechanism for the inhibition of particulate guanylyl cyclases by the natriuretic peptide clearance receptor

  2023cites this paper
• Emerging tools for studying receptor endocytosis and signaling.

  2023cites this paper
• Natriuretic peptide receptor-C releases and activates guanine nucleotide-exchange factor H1 in a ligand-dependent manner.

  2021cites this paper
• Emerging concepts of receptor endocytosis and concurrent intracellular signaling: Mechanisms of guanylyl cyclase/natriuretic peptide receptor-A activation and trafficking.

  2019cites this paper
• Clathrin-dependent internalization, signaling, and metabolic processing of guanylyl cyclase/natriuretic peptide receptor-A

  2017cites this paper
• Endocytosis and Trafficking of Natriuretic Peptide Receptor-A: Potential Role of Short Sequence Motifs

  2015cites this paper
• GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer

  2014cites this paper
• Noninvasive imaging of focal atherosclerotic lesions using fluorescence molecular tomography

  2014cites this paper
• Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes

  2013cites this paper
• Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.

  2011cites this paper