The Role of Biomarkers in Detecting Early Changes Relating to Exposure to Occupational Carcinogens

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Journal of Occupational Health

• Publication date

  1996-10-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1539/joh.38.170
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1970cited by this paper
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  1954cited by this paper
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  1941cited by this paper
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