Expression of Bub1 Gene Correlates with Tumor Proliferating Activity in Human Gastric Carcinomas

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Pathobiology (Basel)

• Publication date

  2001-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000048754PMID 11641614
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• p53 point mutations in primary human gastric carcinomas

  2005cited by this paper
• AJCC Cancer Staging Manual

  2002cited by this paper
• Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast cancer cell lines.

  2000cited by this paper
• Mutational Inactivation of Mitotic Checkpoint Genes, hsMAD2 and hBUB1, Is Rare in Sporadic Digestive Tract Cancers

  1999cited by this paper
• Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines.

  1999cited by this paper
• The mouse mitotic checkpoint gene bub1b, a novel bub1 family member, is expressed in a cell cycle-dependent manner.

  1999cited by this paper
• Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the Spindle Checkpoint and the Preservation of Correct Ploidy through Mitosis

  1998cited by this paper
• Mutations of mitotic checkpoint genes in human cancers

  1998cited by this paper
• Human Bub1: a putative spindle checkpoint kinase closely linked to cell proliferation.

  1998cited by this paper
• Reduced Expression of Cyclin–dependent Kinase Inhibitor p27Kipl Is Associated with Advanced Stage and Invasiveness of Gastric Carcinomas

  1997cited by this paper
• Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage.

  1997cited by this paper
• The spindle assembly checkpoint.

  1996cited by this paper
• Expression of cyclin E in colorectal adenomas and adenocarcinomas: correlation with expression of Ki-67 antigen and p53 protein

  1996cited by this paper
• Abnormal kinetochore structure activates the spindle assembly checkpoint in budding yeast.

  1996cited by this paper
• Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast

  1995cited by this paper
• The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase.

  1994cited by this paper
• DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.

  1992cited by this paper
• Prognostic value of proliferating cell nuclear antigen in gastric carcinoma.

  1991cited by this paper
• S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function.

  1991cited by this paper
• Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle.

  1990cited by this paper
• Growth fractions in gastric carcinomas determined with monoclonal antibody Ki‐67

  1990cited by this paper
• Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissues. Comparison with flow cytometric analysis.

  1989cited by this paper
• Monoclonal antibodies to proliferating cell nuclear antigen (PCNA)/cyclin as probes for proliferating cells by immunofluorescence microscopy and flow cytometry.

  1988cited by this paper

• Budding Uninhibited by Benzimidazole 1 in pancreatic cancer: theoretical, mechanistic and bioinformatic insights

  2025cites this paper
• Transcriptomics-based liquid biopsy panel for early non-invasive identification of peritoneal recurrence and micrometastasis in locally advanced gastric cancer

  2024cites this paper
• BUB1 potentiates gastric cancer proliferation and metastasis by activating TRAF6/NF-κB/FGF18 through m6A modification.

  2024cites this paper
• Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies

  2024cites this paper
• Identification of GNG7 as a novel biomarker and potential therapeutic target for gastric cancer via bioinformatic analysis and in vitro experiments

  2023cites this paper
• Development and veri�cation of pyroptosis scoring system of lower-grade gliomas

  2023cites this paper
• Construction of novel lncRNA-miRNA-mRNA ceRNA networks associated with prognosis of hepatitis C virus related hepatocellular carcinoma

  2022cites this paper
• Increased Expression of VANGL1 Is Predictive of Lymph Node Metastasis in Colorectal Cancer: Results from a 20-Gene Expression Signature

  2021cites this paper
• Identification of key molecular markers in epithelial ovarian cancer by integrated bioinformatics analysis.

  2021cites this paper
• Inhibition of BUB1 suppresses tumorigenesis of osteosarcoma via blocking of PI3K/Akt and ERK pathways

  2021cites this paper
• Prognostic Value of BUB1 for Predicting Non-Muscle-Invasive Bladder Cancer Progression

  2021cites this paper
• Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma

  2020cites this paper
• Gene Activation as a Cell Protection Mechanism Against Gamma-Ray radiation.

  2020cites this paper
• Prognostic Prediction Using a Stemness Index-Related Signature in a Cohort of Gastric Cancer

  2020cites this paper
• Screening and identification of key biomarkers and related transcription factors in ovarian cancer by integrated bioinformatics analysis

  2020cites this paper
• Gene Activation as a Cell Protection Mechanism Against Gamma-Ray radiation

  2020cites this paper
• Identifying candidate diagnostic markers for early stage of non-small cell lung cancer

  2019cites this paper
• Serine/threonine kinase BUB1 promotes proliferation and radio-resistance in glioblastoma.

  2019cites this paper
• The Association Between AURKA Gene rs2273535 Polymorphism and Gastric Cancer Risk in a Chinese Population

  2018cites this paper
• Aneuploidy: Cancer strength or vulnerability?

  2018cites this paper
• Mutation status coupled with RNA-sequencing data can efficiently identify important non-significantly mutated genes serving as diagnostic biomarkers of endometrial cancer

  2017cites this paper
• Low BUB1 expression is an adverse prognostic marker in gastric adenocarcinoma

  2017cites this paper
• HMGA1 knock-down induces autophagy through regulation of ULK gene expression in cancer cells

  2016cites this paper
• Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities

  2016cites this paper
• Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes

  2015cites this paper
• Biological and Clinical Significance of MAD2L1 and BUB1, Genes Frequently Appearing in Expression Signatures for Breast Cancer Prognosis

  2015cites this paper
• Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

  2014influential citation
• BUB1 Immunolocalization in Breast Carcinoma: Its Nuclear Localization as a Potent Prognostic Factor of the Patients

  2013cites this paper
• Potential Role of Meiosis Proteins in Melanoma Chromosomal Instability

  2013cites this paper
• Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons

  2012cites this paper
• Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation

  2011cites this paper
• Bub1 overexpression induces aneuploidy and tumor formation through Aurora B kinase hyperactivation

  2011cites this paper
• The spindle assembly checkpoint: perspectives in tumorigenesis and cancer therapy

  2011cites this paper
• BUB3 that dissociates from BUB1 activates caspase-independent mitotic death (CIMD)

  2010cites this paper
• Mitotic Checkpoint and Chromosome Instability in Cancer

  2010cites this paper
• Bub1 regulates chromosome segregation in a kinetochore-independent manner

  2009cites this paper
• Caspase-independent mitotic death

  2009cites this paper
• Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.

  2009cites this paper
• The mitotic checkpoint: mechanism and biological relevance

  2008cites this paper
• Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature.

  2008cites this paper
• Preventing aneuploidy: the contribution of mitotic checkpoint proteins.

  2008cites this paper
• Aneuploidy in upper gastro-intestinal tract cancers--a potential prognostic marker?

  2008cites this paper
• Caspase-independent mitotic death (CIMD)

  2008cites this paper
• Characterization of a murine hypomorphic allele of the spindle checkpoint gene Bub1 and its role in tumorigenesis

  2008cites this paper
• Human MOB1 expression in non-small-cell lung cancer.

  2007cites this paper
• Bub1: Escapades in a Cellular World

  2007cites this paper
• Analysis of anaphase inhibitors in fission yeast

  2007cites this paper
• Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

  2007cites this paper
• BUB1 mediation of caspase-independent mitotic death determines cell fate

  2007cites this paper
• Correlation of human Bub 1 expression with tumor-proliferating activity in salivary gland tumors

  2006cites this paper
• Correlation of human Bub1 expression with tumor-proliferating activity in salivary gland tumors.

  2006cites this paper
• DNA methylation of CHFR is not a predictor of the response to docetaxel and paclitaxel in advanced and recurrent gastric cancer.

  2006cites this paper
• Does aneuploidy cause cancer?

  2006cites this paper
• Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett's oesophagus-their association with aneuploidy and neoplastic progression.

  2004cites this paper
• The spindle checkpoint: from normal cell division to tumorigenesis.

  2003cites this paper
• Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization

  2003cites this paper
• Jcb: Article Introduction

  2002cites this paper
• No mutations of the Bub1 gene in human gastric and oral cancer cell lines.

  2002cites this paper
• Jcb: Article

  year unknowncites this paper
• Oncotargets and Therapy Dovepress Identifying Module Biomarkers from Gastric Cancer by Differential Correlation Network

  year unknowncites this paper
• Jcb: Article

  year unknowncites this paper