New Targets for the Identification of an Anti-Inflammatory Anti-Senescence Activity

Aging is necessarily associated to cell senescence, but is it its sole motor or phenomenon? Replicative cell senescence can be accelerated by stress, inflammation and uneven life conditions. We talk about stress-induced premature senescence when cell metabolism is exposed to a systemic profile of cortisol and catecholamines and inflammation is maintained by a high profile of cytokines. These latter are detrimental for cells and stem-cells, accelerating the senescence of both.

• Publication year

  2012

• Venue

  Unknown venue

• Publication date

  2012-02-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.5772/34303
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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