Aumento de Volume Gengival Induzido por Fármacos

Abstract Drug induced gingival enlargement (DIGE) is characterized by a gingival enlargementwhich can reach just one area or involve several areas, mainly anterior regions of maxilla and mandible. The cyclosporine, phenytoin and nifedipine are the mainly drugs related with DIGE. Several risk factors are involved, as bacterial plaque. The pathogenesis is controversial, but most of the studies agree with the participation of genetic susceptibility, growth factors and fibroblasts. The prevention approaches in patients under this therapy programme are essential, and also the early diagnosis and follow-up, to minimize the adverse consequences and reduce the prevalence and severity of gingival enlargement.

• Publication year

  2010

• Venue

  Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial

• Publication date

  2010-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S1646-2890(10)70007-8
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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