Emerging roles of ATF3 in the suppression of prostate cancer

Stress response mediator activating transcription factor 3 (ATF3) engages in diverse oncogenic pathways including the androgen receptor signaling essential for prostatic proliferation. In line with frequent downregulation of ATF3 expression in human prostate cancers, we have provided the first genetic evidence supporting the role of ATF3 as a tumor suppressor in a subset of prostate cancers with PTEN dysfunction.

• Publication year

  2015

• Venue

  Molecular & Cellular Oncology

• Publication date

  2015-02-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/23723556.2015.1010948PMID 27308526PMCID 4845162
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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