Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  American Journal of Physiology. Regulatory Integrative and Comparative Physiology

• Publication date

  2008-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPREGU.00628.2007PMID 18077510
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progesterone withdrawal as the lactogenic trigger in the rat

  2009cited by this paper
• Normal lactational environment restores nephron endowment and prevents hypertension after placental restriction in the rat.

  2007cited by this paper
• Stress during gestation alters postpartum maternal care and the development of the offspring in a rodent model.

  2006cited by this paper
• Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers.

  2005cited by this paper
• a-Lactalbumin and lactose concentrations in rat milk during lactation

  2005cited by this paper
• Trajectories of growth among children who have coronary events as adults.

  2005cited by this paper
• Uteroplacental restriction in the rat impairs fetal growth in association with alterations in placental growth factors including PTHrP.

  2005cited by this paper
• Measuring stress responses in postpartum mothers: Perspectives from studies in human and animal populations

  2005cited by this paper
• Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth

  2004cited by this paper
• Hot topic: effects of frequent milking in early lactation on milk yield and udder health.

  2004cited by this paper
• Hormonal Regulation of Mammary Differentiation and Milk Secretion

  2004cited by this paper
• Pups Presence Eliminates the Stress Hyporesponsiveness of Early Lactating Females to a Psychological Stress Representing a Threat to the Pups

  2003cited by this paper
• Milk yield and mammary growth effects due to increased milking frequency during early lactation.

  2003cited by this paper
• the rat

  2003cited by this paper
• Impaired mammary function and parathyroid hormone-related protein during lactation in growth-restricted spontaneously hypertensive rats.

  2003cited by this paper
• Is birth weight related to later glucose and insulin metabolism?—a systematic review

  2003cited by this paper
• Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life

  2003cited by this paper
• Intrauterine growth retardation leads to the development of type 2 diabetes in the rat.

  2001cited by this paper
• Reduced fetal, placental, and amniotic fluid PTHrP in the growth-restricted spontaneously hypertensive rat.

  2000cited by this paper
• Endocrine regulation and extended follow up of longitudinal growth in intrauterine growth-retarded rats.

  2000cited by this paper
• Milk and Diabetes

  2000cited by this paper
• Interactions of perturbations in intrauterine growth and growth during childhood on the risk of adult-onset disease

  2000cited by this paper
• The influence of suckling interval on milk production of sows.

  2000cited by this paper
• Catch-up growth in childhood and death from coronary heart disease: longitudinal study

  1999cited by this paper
• Education and debate

  1999cited by this paper
• Effect of intrauterine growth restriction on blood pressure, glucose tolerance and sympathetic nervous system activity in the rat at 3-4 months of age.

  1999cited by this paper
• Alteration of the sodium to potassium ratio in milk and the effect on milk secretion in goats.

  1999influential reference
• Observations on the Orexigenic Hypothalamic Neuropeptide Y‐System in Neonatally Overfed Weanling Rats

  1999cited by this paper
• Expression of PTHrP and the PTH/PTHrP receptor in purified alveolar epithelial cells, myoepithelial cells, and stromal fibroblasts derived from the lactating rat mammary gland.

  1999cited by this paper
• Comparison of weigh-suckle-weigh and machine milking for measuring ewe milk production.

  1999cited by this paper
• Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development.

  1998cited by this paper
• Intrauterine Growth Retardation Alters Mitochondrial Gene Expression and Function in Fetal and Juvenile Rat Skeletal Muscle

  1998cited by this paper
• Effect of Uteroplacental Insufficiency upon Brain Neuropeptide Y and Corticotropin-Releasing Factor Gene Expression and Concentrations1

  1998cited by this paper
• Autocrine regulation of milk secretion.

  1998influential reference
• Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation.

  1997cited by this paper
• Breastfeeding and incidence of non-insulin-dependent diabetes mellitus in Pima Indians.

  1997cited by this paper
• Defining the roles of parathyroid hormone-related protein in normal physiology.

  1996cited by this paper
• Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor.

  1996cited by this paper
• Parathyroid Hormone-Related Protein

  1995cited by this paper
• Integrin alpha 2 beta 1 mediates interactions between developing embryonic retinal cells and collagen.

  1995cited by this paper
• Parathyroid hormone-related protein.

  1995cited by this paper
• Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development.

  1995cited by this paper
• Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

  1994cited by this paper
• Cow's Milk Exposure and Type I Diabetes Mellitus: A critical overview of the clinical literature

  1994cited by this paper
• Circulating levels of insulin, insulin-like growth factor-I (IGF-I), IGF-II, and IGF-binding proteins in the small for gestational age fetal rat.

  1993cited by this paper
• Glucocorticoid exposure in utero: new model for adult hypertension.

  1993cited by this paper
• Mammary gland differentiation in hypophysectomized, pregnant mice treated with corticosterone and thyroxine.

  1992cited by this paper
• Collection of fore and hind milk from the sow and the changes in milk composition during suckling

  1992cited by this paper
• Parathyroid hormone-related protein: elevated levels in both humoral hypercalcemia of malignancy and hypercalcemia complicating metastatic breast cancer.

  1991cited by this paper
• [Parathyroid hormone-related peptide (PTHrP)].

  1990cited by this paper
• Milk Lactose, Citrate, and Glucose as Markers of Lactogenesis in Normal and Diabetic Women

  1989influential reference
• Altered Growth, Hypoglycemia, Hypoalaninemia, and Ketonemia in the Young Rat: Postnatal Consequences of Intrauterine Growth Retardation

  1985cited by this paper
• The Mechanisms of Milk Secretion

  1983cited by this paper
• Influence of meclofenamic acid on the initiation of parturition and lactation in the sow.

  1982cited by this paper
• Failure of lactogenesis associated with placental retention.

  1981cited by this paper
• Alpha-Lactalbumin and lactose concentrations in rat milk during lactation.

  1981cited by this paper
• The foetoplacental unit and the initiation of lactation in the rat.

  1981cited by this paper
• Milk yield, suckling behaviour and milk ejection in the lactating rat nursing litters of different sizes.

  1980cited by this paper
• Long-term effects of early nutritional experience on the development of obesity in the rat.

  1980cited by this paper
• Ultrastructural alterations in mammary glands of pregnant rats after ovariectomy and hysterectomy: effect of adrenal steroids and prolactin.

  1979cited by this paper
• Prolactin release and lactogenesis after ovariectomy in pregnant rats: effect of ovarian hormones.

  1974cited by this paper
• The persistence of progesterone secretion in pregnant rats after hypophysectomy and hysterectomy: a comparison with pseudopregnant, deciduomata-bearing pseudopregnant, and lactating rats.

  1973cited by this paper
• Porlactin production and lactogenesis in rats after ovariectomy in late pregnancy.

  1973cited by this paper
• Onset and duration of the physiological weaning period for infant rats reared in nests of different sizes.

  1973cited by this paper
• Neonatal hypocalcemia in low birth weight infants.

  1970cited by this paper
• Progesterone withdrawal as the lactogenic trigger in the rat.

  1969cited by this paper
• Lactogenesis in the rat. Changes in metabolic parameters at parturition.

  1967cited by this paper
• A Rapid and Simple Method for the Determination of Esterified Fatty Acids and for Total Fatty Acids in Blood

  1953cited by this paper
• The let-down reflex in human lactation.

  1948cited by this paper

• Early-Life Hydrogen Sulfide Signaling as a Target for Cardiovascular–Kidney–Metabolic Syndrome Reprogramming

  2025cites this paper
• Metformin and insulin exacerbate one‐carbon metabolism deficits in pregnant growth restricted rats and impacts the placenta, fetal liver and pancreas

  2025cites this paper
• Breastfeeding and Future Cardiovascular, Kidney, and Metabolic Health—A Narrative Review

  2025cites this paper
• Animal Models for Studying Developmental Origins of Cardiovascular–Kidney–Metabolic Syndrome

  2025cites this paper
• Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

  2025cites this paper
• Unraveling the persistent renal impact of intrauterine growth restriction and catch-up growth: integrating morphological insights with metabolomic profiling

  2025cites this paper
• The prospective associations of fetal growth-related pregnancy complications with subsequent breastfeeding duration and markers of human milk production.

  2024cites this paper
• Infant factors that impact the ecology of human milk secretion and composition—a report from “Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN)” Working Group 3

  2023cites this paper
• Postnatal persistence of nonhuman primate sex‐dependent renal structural and molecular changes programmed by intrauterine growth restriction

  2022cites this paper
• The effects of oil sands process-affected water naphthenic acid fraction components on GDF15 secretion in extravillous trophoblast cells.

  2022cites this paper
• Can we modulate the breastfed infant gut microbiota through maternal diet?

  2021cites this paper
• Cross talk of vascular endothelial growth factor and neurotrophins in mammary gland development

  2020cites this paper
• Effects of intrauterine growth restriction on Ca2+-activated force and contractile protein expression in the mesenteric artery of 1-year-old Wistar-Kyoto rats

  2020cites this paper
• Postnatal persistence of sex-dependent renal developmentally programmed structural and molecular changes in nonhuman primates

  2020cites this paper
• Parenterally Delivered Methionyl-Methionine Dipeptide During Pregnancy Enhances Mammogenesis and Lactation Performance Over Free Methionine by Activating PI3K-AKT Signaling in Methionine-Deficient Mice.

  2020cites this paper
• Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress

  2020cites this paper
• Reducing Pup Litter Size Alters Early Postnatal Calcium Homeostasis and Programs Adverse Adult Cardiovascular and Bone Health in Male Rats

  2019cites this paper
• MULTIPLE EFFECTS OF PREECLAMPSIA IN COWS ON POSTNATAL GROWTH AND HEALTH OF OFFSPRING

  2019cites this paper
• Treadmill Exercise before and during Pregnancy Improves Bone Deficits in Pregnant Growth Restricted Rats without the Exacerbated Effects of High Fat Diet

  2019cites this paper
• Preclinical Models of Altered Early Life Nutrition and Development of Reproductive Disorders in Female Offspring.

  2019cites this paper
• The transgenerational effect of maternal and paternal F1 low birth weight on bone health of second and third generation offspring

  2018cites this paper
• Maternal stress does not exacerbate long-term bone deficits in female rats born growth restricted, with differential effects on offspring bone health.

  2018cites this paper
• Fetal growth restriction shortens cardiac telomere length, but this is attenuated by exercise in early life.

  2018cites this paper
• Angiotensin receptor blockade in juvenile male rat offspring: Implications for long‐term cardio‐renal health

  2018cites this paper
• The effect of intrauterine growth restriction on Ca2+‐activated force and contractile protein expression in the mesenteric artery of adult (6‐month‐old) male and female Wistar‐Kyoto rats

  2018cites this paper
• Adolescence and the next generation

  2018cites this paper
• Intrauterine Growth Restriction Alters the Postnatal Development of the Rat Cerebellum

  2017cites this paper
• The highs and lows of programmed cardiovascular disease by developmental hypoxia: studies in the chicken embryo

  2017cites this paper
• Uteroplacental insufficiency reduces rat plasma leptin concentrations and alters placental leptin transporters: ameliorated with enhanced milk intake and nutrition

  2017cites this paper
• Placental restriction in multi-fetal pregnancies and between-twin differences in size at birth alter neonatal feeding behaviour in the sheep

  2017cites this paper
• Prenatal Mechanistic Target of Rapamycin Complex 1 (m TORC1) Inhibition by Rapamycin Treatment of Pregnant Mice Causes Intrauterine Growth Restriction and Alters Postnatal Cardiac Growth, Morphology, and Function

  2017cites this paper
• Multi-hit hypothesis in kidney development: Drug effects and interactions with extrauterine growth restriction

  2016cites this paper
• The Programming Power of the Placenta

  2016cites this paper
• Endurance training in early life results in long‐term programming of heart mass in rats

  2016influential citation
• Adrenal, metabolic and cardio‐renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy

  2016cites this paper
• METABOLIC STATUS OF THE COWS UNDER INTRAUTERINE GROWTH RETARDATION OF EMBRYO AND FETUS

  2016cites this paper
• Late gestational hypoxia and a postnatal high salt diet programs endothelial dysfunction and arterial stiffness in adult mouse offspring

  2016cites this paper
• Sex-Specific Metabolic Outcomes in Offspring of Female Rats Born Small or Exposed to Stress During Pregnancy.

  2016cites this paper
• A review of fundamental principles for animal models of DOHaD research: an Australian perspective.

  2016cites this paper
• [Malnutrition in early life and cardiovascular disease in adulthood].

  2015cites this paper
• Developmental programming of bone deficits in growth-restricted offspring.

  2015influential citation
• Leptin in pregnancy and development: a contributor to adulthood disease?

  2015cites this paper
• Uteroplacental insufficiency leads to hypertension, but not glucose intolerance or impaired skeletal muscle mitochondrial biogenesis, in 12-month-old rats

  2015cites this paper
• Developmental Origins of Health and Disease Effect of prenatal programming and postnatal rearing on glomerular filtration rate in adult rats

  2015cites this paper
• Puberty onset is delayed following uteroplacental insufficiency and occurs earlier with improved lactation and growth for pups born small.

  2015influential citation
• Pregnant growth restricted female rats have bone gains during late gestation which contributes to second generation adolescent and adult offspring having normal bone health.

  2015cites this paper
• Transgenerational programming of fetal nephron deficits and sex-specific adult hypertension in rats.

  2014cites this paper
• The role of female reproductive history in determining variation in cortical bone remodeling and trabecular architecture in a nonhuman animal model (Papio hamadryas)

  2014cites this paper
• Histometric evaluation of dental alveolar repair in malnourished rats in the intrauterine or postnatal phase.

  2014cites this paper
• Embryo transfer cannot delineate between the maternal pregnancy environment and germ line effects in the transgenerational transmission of disease in rats.

  2014cites this paper
• Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner

  2014cites this paper
• Physiological skeletal gains and losses in rat mothers during pregnancy and lactation are not observed following uteroplacental insufficiency.

  2014cites this paper
• Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction.

  2014cites this paper
• Effect of Postnatal Maternal Protein Intake on Prenatal Programming of Hypertension

  2014cites this paper
• Transgenerational left ventricular hypertrophy and hypertension in offspring after uteroplacental insufficiency in male rats

  2014cites this paper
• Growth restriction in the rat alters expression of metabolic genes during postnatal cardiac development in a sex-specific manner.

  2013cites this paper
• Transgenerational metabolic outcomes associated with uteroplacental insufficiency.

  2013cites this paper
• CALL FOR PAPERS Fetal and Neonatal Programming: Epigenetic Modification of Phenotype The effect of low-to-moderate-dose ethanol consumption on rat mammary gland structure and function and early postnatal growth of offspring

  2013cites this paper
• Comparison of the effect of maternal hypothyroidism on carbohydrate metabolism in young and aged male offspring in rats

  2013cites this paper
• a sex-specific manner metabolic genes during postnatal cardiac development in Growth restriction in the rat alters expression of

  2013cites this paper
• Avaliação das consequências da limitação do tamanho da prole de ratos Wistar ao nascimento sobre seu desenvolvimento ponderal e características morfofuncionais na idade adulta

  2013cites this paper
• Developmental programming: Variations in early growth and adult disease

  2013cites this paper
• Uteroplacental insufficiency programmes vascular dysfunction in non‐pregnant rats: compensatory adaptations in pregnancy

  2012cites this paper
• Effects of ciprofloxacin and zinc chloride in adult albino rat and pre-natal conceptus.

  2012cites this paper
• Uteroplacental Insufficiency and Lactational Environment Separately Influence Arterial Stiffness and Vascular Function in Adult Male Rats

  2012cites this paper
• Effect of Pregnancy for Females Born Small on Later Life Metabolic Disease Risk

  2012cites this paper
• Normal lactational environment restores cardiomyocyte number after uteroplacental insufficiency: implications for the preterm neonate.

  2012cites this paper
• Cardio‐renal and metabolic adaptations during pregnancy in female rats born small: implications for maternal health and second generation fetal growth

  2012cites this paper
• Pregnancy in aged rats that were born small: cardiorenal and metabolic adaptations and second‐generation fetal growth

  2012cites this paper
• Exercise early in life in rats born small does not normalize reductions in skeletal muscle PGC-1α in adulthood.

  2012cites this paper
• Growth restriction alters adult spatial memory and sensorimotor gating in a sex-specific manner

  2011cites this paper
• Stage of perinatal development regulates skeletal muscle mitochondrial biogenesis and myogenic regulatory factor genes with little impact of growth restriction or cross-fostering

  2011cites this paper
• Expression study on the porcine PTHLH gene and its relationship with sow teat number.

  2011cites this paper
• Prenatal Programming of Hypertension in the Rat: Effect of Postnatal Rearing

  2011cites this paper
• growth restriction in adult male rats -cell mass associated with β deficits in pancreatic Short-term exercise training early in life restores

  2011cites this paper
• Short-term exercise training early in life restores deficits in pancreatic β-cell mass associated with growth restriction in adult male rats.

  2011cites this paper
• Role of the kidney in the prenatal and early postnatal programming of hypertension.

  2010cites this paper
• Uteroplacental insufficiency programs regional vascular dysfunction and alters arterial stiffness in female offspring

  2010cites this paper
• Placental Restriction Increases Adipose Leptin Gene Expression and Plasma Leptin and Alters Their Relationship to Feeding Activity in the Young Lamb

  2010cites this paper
• Cross-fostering and improved lactation ameliorates deficits in endocrine pancreatic morphology in growth-restricted adult male rat offspring

  2010cites this paper
• Chronic placental ischemia alters amniotic fluid milieu and results in impaired glucose tolerance, insulin resistance and hyperleptinemia in young rats

  2010cites this paper
• Озонотерапия фетоплацентарной недостаточности новые возможности адаптации новорожденных

  2010cites this paper
• Growth restriction before and after birth increases kinase signaling pathways in the adult rat heart

  2010cites this paper
• Maternal nutrition, low nephron number and arterial hypertension in later life.

  2010cites this paper
• Calcium supplementation does not rescue the programmed adult bone deficits associated with perinatal growth restriction.

  2010cites this paper
• Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats

  2009cites this paper
• Faculdade de Odontologia de Araçatuba-UNESP-Universidade Estadual Paulista

  2009cites this paper
• Early life origins of obesity.

  2009cites this paper
• Modeling intrauterine growth retardation in rodents: Impact on pancreas development and glucose homeostasis.

  2009cites this paper
• Prenatal growth restriction and postnatal growth restriction followed by accelerated growth independently program reduced bone growth and strength.

  2009influential citation
• Developmental programming of a reduced nephron endowment: more than just a baby's birth weight.

  2009cites this paper
• Maternal Progesterone Treatment Rescues the Mammary Impairment Following Uteroplacental Insufficiency and Improves Postnatal Pup Growth in the Rat

  2009cites this paper
• Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.

  2008cites this paper
• Brain Allopregnanolone in the Fetal and Postnatal Rat in Response to Uteroplacental Insufficiency

  2008cites this paper
• Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat.

  2008influential citation
• Glucose Tolerance by Uteroplacental Insufficiency in Male Rat Offspring Improved Lactational Nutrition and Postnatal Growth Ameliorates Impairment of

  2008cites this paper
• Uteroplacental insufficiency alters the mammary gland response to lactogenic hormones in vitro.

  2008cites this paper
• Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats.

  2008influential citation