5‐fluorouracil‐related gene expression levels in primary colorectal cancer and corresponding liver metastasis

No abstract is available for this paper.

• Publication year

  2006

• Venue

  International Journal of Cancer

• Publication date

  2006-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ijc.21692PMID 16572420
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cancer Statistics, 2004

  2004cited by this paper
• Role of cancer-associated stromal fibroblasts in metastatic colon cancer to the liver and their expression profiles

  2004cited by this paper
• Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis

  2004influential reference
• Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers.

  2004cited by this paper
• Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer

  2003cited by this paper
• Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases.

  2002cited by this paper
• Intratumoral dihydropyrimidine dehydrogenase messenger RNA level reflects tumor progression in human colorectal cancer

  2002cited by this paper
• Thymidine phosphorylase and vascular endothelial growth factor in patients with Stage I lung adenocarcinoma

  2002cited by this paper
• Immunohistochemical localization of platelet-derived endothelial cell growth factor expression and its relation to angiogenesis in prostate.

  2001cited by this paper
• Thymidine phosphorylase and dihydropyrimidine dehydrogenase protein expression in colorectal cancer

  2001cited by this paper
• Thymidylate synthase gene expression in primary colorectal cancer and metastatic sites.

  2001cited by this paper
• Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

  2000cited by this paper
• Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans

  2000cited by this paper
• Telomerase reverse transcriptase expression is increased early in the Barrett’s metaplasia, dysplasia, adenocarcinoma sequence

  2000cited by this paper
• Expression of platelet‐derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma

  2000cited by this paper
• Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues.

  2000cited by this paper
• Gene expression for dihydropyrimidine dehydrogenase and thymidine phosphorylase influences outcome in epithelial ovarian cancer.

  2000cited by this paper
• Thymidine phosphorylase expression in tumor stroma of uterine cervical carcinomas: histological features and microvessel density.

  2000cited by this paper
• Prognostic role of thymidylate synthase, thymidine phosphorylase/platelet-derived endothelial cell growth factor, and proliferation markers in colorectal cancer.

  2000cited by this paper
• Regulation of dihydropyrimidine dehydrogenase in colorectal cancer.

  1999cited by this paper
• Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer.

  1999cited by this paper
• High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.

  1998cited by this paper
• Structural organization of the human dihydropyrimidine dehydrogenase gene.

  1997cited by this paper
• Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin.

  1997cited by this paper
• Laser Capture Microdissection: Molecular Analysis of Tissue

  1997cited by this paper
• A novel method for real time quantitative RT-PCR.

  1996cited by this paper
• Real time quantitative PCR.

  1996cited by this paper
• Chemotherapy for colorectal cancer.

  1994cited by this paper
• Purification and characterization of dihydropyrimidine dehydrogenase from human liver.

  1992cited by this paper
• Chemotherapy of colorectal cancer.

  1991cited by this paper
• Cancer statistics

  1989cited by this paper
• Enzymes of uracil catabolism in normal and neoplastic human tissues.

  1985cited by this paper

• Capacity of Thymidylate Synthase and Dihydropyrimidine Dehydrogenase mRNA Expression to Predict Neoadjuvant Chemotherapy Response of 5fu Regimen in Advanced Colorectal Cancer: A Cross-Sectional Study

  2025cites this paper
• 5‐Fluorouracil metabolic pathway genes predict recurrence risk following adjuvant S‐1 therapy: Results of an ancillary analysis from a phase III trial of resected biliary tract cancer (JCOG1202A1)

  2024cites this paper
• Elevated levels of mRNAs encoding dihydropyrimidine dehydrogenase and thymidylate synthase are associated with improved survival of patients with hepatocellular carcinoma treated with S-1.

  2017cites this paper
• Prognostic value of biomarkers in metastatic colorectal cancer patients.

  2015cites this paper
• Experimental and population-based studies on colorectal cancer - Thymidine phosphorylase as a potential biomarker

  2014cites this paper
• Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer

  2014cites this paper
• Biological resonance for cancer metastasis, a new hypothesis based on comparisons between primary cancers and metastases

  2013cites this paper
• Expression of HGF and Met in Human Tissues of Colorectal Cancers: Biological and Clinical Implications for Synchronous Liver Metastasis

  2013cites this paper
• Thymidylate synthase and thymidine phosphorylase mRNA expression in primary lesions using laser capture microdissection is useful for prediction of the efficacy of FOLFOX treatment in colorectal cancer patients with liver metastasis.

  2012cites this paper
• Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases

  2012cites this paper
• A pilot study of mRNA expressions of 5-fluorouracil pathway genes in peripheral blood mononuclear cells and tumor tissues in patients with lung adenocarcinoma.

  2011cites this paper
• Metastatic lymph node targeted chemosensitivity test for gastric cancer.

  2011cites this paper
• S-1 and the treatment of gastric cancer with peritoneal dissemination.

  2011cites this paper
• Determinants of antifolate and 5-fluorouracil efficacy

  2011cites this paper
• Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti‐metastatic efficacy between oral S‐1 and UFT/ LV

  2010cites this paper
• Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases

  2010cites this paper
• Correlation between Efficacy of Irinotecan and Thymidylate Synthase in Colorectal Cancer

  2010cites this paper
• Thymidylate synthase expression and mismatch repair protein expression in colorectal cancer

  2010cites this paper
• Telomere length, telomeric proteins and DNA damage repair proteins are differentially expressed between primary lung tumors and their adrenal metastases.

  2009cites this paper
• Polymorphisms in the enhancer region of the thymidylate synthase gene are associated with thymidylate synthase levels in normal tissues but not in malignant tissues of patients with colorectal cancer.

  2009cites this paper
• Expression of 5-fluorouracil-related enzymes in lung cancer: ELISA characterizes enzyme activity and messenger RNA expression.

  2009cites this paper
• Dihydropyrimidine dehydrogenase mRNA expression in peripheral blood of rectal cancer patients is significantly associated with residual tumor and distant metastases following resection

  2009cites this paper
• A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?

  2009cites this paper
• Predikce chemosenzitivity na 5-fluorouracil a jeho deriváty u nemocných léčených chemoterapií pro kolorektální karcinom

  2009cites this paper
• Molecular determinants of efficacy for 5‐FU‐based treatments in advanced colorectal cancer: mRNA expression for 18 chemotherapy‐related genes

  2009cites this paper
• Thymidylate Synthase and Dihydropyrimidine Dehydrogenase Are Upregulated in Pancreatic and Biliary Tract Cancers

  2009cites this paper
• Both β‐actin and GAPDH are useful reference genes for normalization of quantitative RT‐PCR in human FFPE tissue samples of prostate cancer

  2008cites this paper
• High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1

  2008cites this paper
• Thymidylate synthase polymorphisms and mRNA expression are independent chemotherapy predictive markers in esophageal adenocarcinoma patients.

  2008cites this paper
• Combination of O6-methylguanine-DNA methyltransferase and thymidylate synthase for the prediction of fluoropyrimidine efficacy.

  2008cites this paper
• 5-Fluorouracil-related gene expression in hepatic artery infusion-treated patients with hepatic metastases from colorectal carcinomas.

  2008cites this paper
• Expression of orotate phosphoribosyltransferase in colorectal carcinoma: an immunohistochemical analysis in several components of neoplastic lesions.

  2008cites this paper
• Decreased expression of thymidine phosphorylase/platelet‐derived endothelial cell growth factor in basal cell carcinomas

  2008cites this paper
• 5-Fluorouracil-related gene expression in primary sites and hepatic metastases of colorectal carcinomas.

  2008cites this paper
• Expression of thymidylate synthase in liver and lung metastases of colorectal cancer and their matched primary tumours.

  2008cites this paper
• Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine

  2008cites this paper
• Predictive and prognostic markers in colorectal cancer.

  2007cites this paper
• Predictive molecular markers for colorectal cancer patients with resected liver metastasis and adjuvant chemotherapy.

  2007cites this paper
• Gene expression profile of 5-fluorouracil metabolic enzymes in primary colorectal cancer: potential as predictive parameters for response to fluorouracil-based chemotherapy.

  2007cites this paper
• Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy

  2007cites this paper
• Determinants of Antifolate and 5‐fluorouracil Efficacy Determinants of Antifolate and 5‐fluorouracil Efficacy

  year unknowncites this paper