Genotypic anomaly in Ebola virus strains circulating in Magazine Wharf area, Freetown, Sierra Leone, 2015.

S. Smits,S. Pas,C. Reusken,B. Haagmans,Peirro Pertile,C. Cancedda,K. Dierberg,Isata Wurie,A. Kamara,D. Kargbo,S. Caddy,A. Arias,Lucy G. Thorne,Jia Lu,U. Jah,I. Goodfellow,M. Koopmans

Published 2015 in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

ABSTRACT

The Magazine Wharf area, Freetown, Sierra Leone was a focus of ongoing Ebola virus transmission from late June 2015. Viral genomes linked to this area contain a series of 13 T to C substitutions in a 150 base pair intergenic region downstream of viral protein 40 open reading frame, similar to the Ebolavirus/H.sapiens-wt/SLE/2014/Makona-J0169 strain (J0169) detected in the same town in November 2014. This suggests that recently circulating viruses from Freetown descend from a J0169-like virus.

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