Nitric oxide and the respiratory enzyme.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochimica et Biophysica Acta

• Publication date

  2006-09-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BBABIO.2006.05.011PMID 16792997
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase.

  2006influential reference
• Nitric oxide, cytochrome c oxidase and myoglobin: Competition and reaction pathways

  2005cited by this paper
• Nitroxia: the pathological consequence of dysfunction in the nitric oxide-cytochrome c oxidase signaling pathway.

  2005cited by this paper
• A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus.

  2005cited by this paper
• Mitochondrial type I nitric oxide synthase physically interacts with cytochrome c oxidase.

  2005cited by this paper
• Mitochondrial nitric oxide synthase.

  2005cited by this paper
• Cytochrome c oxidase, ligands and electrons.

  2005cited by this paper
• Control of cytochrome c oxidase activity by nitric oxide.

  2004cited by this paper
• Mitochondrial nitric oxide synthase.

  2004cited by this paper
• Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway

  2004cited by this paper
• Mitochondrial Nitric-Oxide Synthase: Enzyme Expression, Characterization, and Regulation

  2004cited by this paper
• Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase.

  2004cited by this paper
• On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide.

  2004cited by this paper
• Nitric oxide and cytochrome oxidase: reaction mechanisms from the enzyme to the cell.

  2003cited by this paper
• Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion.

  2003cited by this paper
• Reversible Inhibition of Cytochrome c Oxidase by Peroxynitrite Proceeds through Ascorbate-dependent Generation of Nitric Oxide*

  2003cited by this paper
• Characterization and function of mitochondrial nitric-oxide synthase.

  2003cited by this paper
• Endothelial NO formation does not control myocardial O2 consumption in mouse heart.

  2003cited by this paper
• A cytochrome c oxidase proton pumping mechanism that excludes the O2 reduction site

  2003cited by this paper
• Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells

  2003cited by this paper
• Redistribution of Intracellular Oxygen in Hypoxia by Nitric Oxide: Effect on HIF1α

  2003cited by this paper
• A discrete water exit pathway in the membrane protein cytochrome c oxidase

  2003cited by this paper
• The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

  2003cited by this paper
• Some recent contributions of FTIR difference spectroscopy to the study of cytochrome oxidase1

  2003cited by this paper
• Hypothesis: the mitochondrial NO(*) signaling pathway, and the transduction of nitrosative to oxidative cell signals: an alternative function for cytochrome C oxidase.

  2002cited by this paper
• Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species.

  2002cited by this paper
• Does nitric oxide modulate mitochondrial energy generation and apoptosis?

  2002influential reference
• Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging.

  2002cited by this paper
• Nitric Oxide Reacts with the Single-electron Reduced Active Site of Cytochrome c Oxidase*

  2002cited by this paper
• The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides.

  2002cited by this paper
• Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector?

  2002cited by this paper
• Myoglobin: A scavenger of bioactive NO.

  2001cited by this paper
• Nitric Oxide and the Control of Firefly Flashing

  2001cited by this paper
• The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2.

  2001cited by this paper
• Nitric oxide, cytochrome-c oxidase and myoglobin.

  2001cited by this paper
• Kinetic and mechanistic studies of the NO*-mediated oxidation of oxymyoglobin and oxyhemoglobin.

  2001cited by this paper
• Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection

  2001cited by this paper
• Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome c oxidase

  2001cited by this paper
• Nitric oxide and cytochrome c oxidase: mechanisms of inhibition and NO degradation.

  2000influential reference
• Structure and mechanism of the aberrant ba3‐cytochrome c oxidase from Thermus thermophilus

  2000cited by this paper
• Reaction of nitric oxide with the turnover intermediates of cytochrome c oxidase: reaction pathway and functional effects.

  2000cited by this paper
• Oxygen activation and reduction in respiration: involvement of redox-active tyrosine 244.

  2000cited by this paper
• How oxygen is activated and reduced in respiration.

  1999cited by this paper
• Modulation of mitochondrial respiration by nitric oxide: investigation by single cell fluorescence microscopy

  1999cited by this paper
• Mass spectrometric determination of dioxygen bond splitting in the "peroxy" intermediate of cytochrome c oxidase.

  1999cited by this paper
• The Cytochrome c Oxidase from Paracoccus denitrificans Does Not Change the Metal Center Ligation upon Reduction*

  1999cited by this paper
• On the mechanism by which vascular endothelial cells regulate their oxygen consumption.

  1999cited by this paper
• Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide

  1999cited by this paper
• Nitric oxide and oxygen utilization: exercise, heart failure and diabetes.

  1999cited by this paper
• A Common Mechanism for the Interaction of Nitric Oxide with the Oxidized Binuclear Centre and Oxygen Intermediates of Cytochromec Oxidase*

  1998cited by this paper
• Purification and Characterization of a Nitric-oxide Synthase from Rat Liver Mitochondria*

  1998cited by this paper
• Chloride Bound to Oxidized Cytochrome c Oxidase Controls the Reaction with Nitric Oxide*

  1998cited by this paper
• Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione.

  1998cited by this paper
• Crystal Structure of Bovine Heart Cytochrome c Oxidase at 2.8 Å Resolution

  1998cited by this paper
• Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment.

  1997cited by this paper
• Nitric oxide ejects electrons from the binuclear centre of cytochrome c oxidase by reacting with oxidised copper: a general mechanism for the interaction of copper proteins with nitric oxide?

  1997cited by this paper
• Nitric oxide synthase activity in mitochondria

  1997cited by this paper
• On the Mechanism of Inhibition of Cytochrome c Oxidase by Nitric Oxide*

  1996cited by this paper
• Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles.

  1996cited by this paper
• The Whole Structure of the 13-Subunit Oxidized Cytochrome c Oxidase at 2.8 Å

  1996cited by this paper
• Role of endothelium-derived nitric oxide in the modulation of canine myocardial mitochondrial respiration in vitro. Implications for the development of heart failure.

  1996cited by this paper
• Mechanism of NO-induced oxidation of myoglobin and hemoglobin.

  1996cited by this paper
• Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide.

  1996cited by this paper
• Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?

  1996cited by this paper
• Cytochrome c oxidase.

  1996cited by this paper
• Kinetic trapping of oxygen in cell respiration

  1996cited by this paper
• 'As prepared' forms of fully oxidised haem/Cu terminal oxidases.

  1996cited by this paper
• Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs.

  1995cited by this paper
• Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration.

  1995cited by this paper
• Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration.

  1995cited by this paper
• Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase

  1995cited by this paper
• Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans

  1995cited by this paper
• Kinetics of Nitric Oxide Autoxidation in Aqueous Solution in the Absence and Presence of Various Reductants. The Nature of the Oxidizing Intermediates

  1995cited by this paper
• Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8 A

  1995cited by this paper
• Nitric oxide. An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption.

  1995cited by this paper
• Immunocytochemical evidence for a mitochondrially located nitric oxide synthase in brain and liver.

  1995cited by this paper
• Endothelial type nitric oxide synthase in skeletal muscle fibers: mitochondrial relationships.

  1995cited by this paper
• Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension.

  1994cited by this paper
• Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

  1994cited by this paper
• Nitric Oxide‐Mediated Inhibition of the Mitochondrial Respiratory Chain in Cultured Astrocytes

  1994cited by this paper
• Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

  1994cited by this paper
• Autoxidation kinetics of aqueous nitric oxide

  1993cited by this paper
• Reaction of hydrogen peroxide with the rapid form of resting cytochrome oxidase.

  1991cited by this paper
• Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

  1991cited by this paper
• Nitric oxide formed by nitrite reductase of Paracoccus denitrificans is sufficiently stable to inhibit cytochrome oxidase activity and is reduced by its reductase under aerobic conditions.

  1990cited by this paper
• Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

  1990cited by this paper
• Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

  1987cited by this paper
• Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

  1987cited by this paper
• Quantification of the contribution of various steps to the control of mitochondrial respiration.

  1982cited by this paper
• Cytochrome c oxidase. Towards a clarification of its structure, interactions and mechanism.

  1980cited by this paper
• Reactions of nitric oxide with cytochrome c oxidase.

  1980cited by this paper
• Oxygen "pulsed" cytochrome c oxidase: functional properties and catalytic relevance.

  1977cited by this paper
• Functional intermediates in the reaction of membrane-bound cytochrome oxidase with oxygen.

  1975cited by this paper
• The invisible copper of cytochrome c oxidase. pH and ATP dependence of its midpoint potential and its role in the oxygen reaction.

  1975cited by this paper
• Studies on partially reduced mammalian cytochrome oxidase. Reactions with carbon monoxide and oxygen.

  1974cited by this paper
• Reactions of cytochrome oxidase with oxygen and carbon monoxide.

  1963influential reference
• The Oxygen Tension of Arterial Blood

  1896cited by this paper
• Über die Wirkung des Kohlenoxyds auf den Stoffwechsel der Hefe

  year unknowninfluential reference
• BIOCHIMICA ET BIOPHYSICA ACTA

  year unknowncited by this paper

• Modulation of GSNOR activity for improved NO homeostasis and flood resilience in plants

  2026cites this paper
• Cytochrome bd-type oxidases and environmental stressors in microbial physiology.

  2025cites this paper
• A Theoretical Analysis of the Effects That the Glycocalyx and the Internal Elastic Lamina Have on Nitric Oxide Concentration Gradients in the Arterial Wall

  2025cites this paper
• Tissue Hypoxia and Associated Innate Immune Factors in Experimental Autoimmune Optic Neuritis

  2024cites this paper
• Modulation of oxidative neurometabolism in ischemia/reperfusion by nitrite.

  2022cites this paper
• Nitric oxide and its role in exercise physiology.

  2021cites this paper
• Nitric Oxide Does Not Inhibit but Is Metabolized by the Cytochrome bcc-aa3 Supercomplex

  2020cites this paper
• Contribution des phytoglobines et des nitrate réductases à la régulation de l’oxyde nitrique et de la fixation de l’azote dans la symbiose Medicago truncatula / Sinorhizobium meliloti

  2019cites this paper
• Pathways of nitric oxide metabolism and operation of phytoglobins in legume nodules: missing links and future directions.

  2018cites this paper
• Nonylphenol and Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide Signaling

  2018cites this paper
• Staphylococcus aureus nitric oxide synthase (saNOS) modulates aerobic respiratory metabolism and cell physiology

  2017cites this paper
• The kallikrein–kinin system in diabetic kidney disease

  2017cites this paper
• Nitric oxide euthanasia: a potential procedure for improving animal welfare and fillet color of tilapia (Oreochromis niloticus)

  2017cites this paper
• An integrated view of changing nutrient availability in model species: the role of signaling in the plant response

  2017cites this paper
• Cytochrome bd and Gaseous Ligands in Bacterial Physiology.

  2017cites this paper
• Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift

  2017cites this paper
• Molecular Docking Studies of PA-824 with Pyridoxine 5'-Phosphate

  2016cites this paper
• Oxidative stress and myocarditis.

  2016cites this paper
• Three toxic gases meet in the mitochondria

  2015cites this paper
• Exercise and NO production: relevance and implications in the cardiopulmonary system

  2015cites this paper
• Molecular Docking Studies of PA-824 with Pyridoxine 5'-Phosphate Oxidase

  2015cites this paper
• Structure-Based Function Prediction of Functionally Unannotated Structures in the PDB: Prediction of ATP, GTP, Sialic Acid, Retinoic Acid and Heme-bound and -Unbound (Free) Nitric Oxide Protein Binding Sites

  2015cites this paper
• Compartmentalization of Reactive Oxygen Species and Nitric Oxide Production in Plant Cells: An Overview

  2015cites this paper
• Plant mitochondria: source and target for nitric oxide.

  2014cites this paper
• Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress.

  2014cites this paper
• VO2 kinetics in supra-anaerobic threshold constant tests allow the visualization and quantification of the O2 saving after cytochrome c oxidase inhibition by aerobic training or nitrate administration.

  2013cites this paper
• New Evidence for Cross Talk between Melatonin and Mitochondria Mediated by a Circadian-Compatible Interaction with Nitric Oxide

  2013cites this paper
• Kinins— The Kallikrein-Kinin System and Oxidative Stress

  2013cites this paper
• Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology

  2013cites this paper
• Nitric Oxide in Human Health and Disease

  2013cites this paper
• Nitric oxide donors: spermine/NO and diethylenetriamine/NO induce ovarian cancer cell death and affect STAT3 and AKT signaling proteins.

  2013cites this paper
• Effects of anesthetics on mitochondrial signaling and function.

  2012cites this paper
• Mitochondria and nitric oxide: chemistry and pathophysiology.

  2012cites this paper
• Cytochrome c oxidase and nitric oxide in action: molecular mechanisms and pathophysiological implications.

  2012cites this paper
• The kallikrein–kinin system and oxidative stress

  2012cites this paper
• Functional evidence for nitric oxide production by skeletal-muscle mitochondria from lipopolysaccharide-treated mice.

  2012cites this paper
• Cytochrome bd oxidase and nitric oxide: From reaction mechanisms to bacterial physiology

  2012cites this paper
• Acquired cytochrome C oxidase impairment in apheresis platelets during storage: a possible mechanism for depletion of metabolic adenosine triphosphate

  2012cites this paper
• Nitroimidazoles for the treatment of TB: past, present and future.

  2011cites this paper
• Newly lesioned tissue in multiple sclerosis--a role for oxidative damage?

  2011cites this paper
• Emblica officinalis Ameliorates Alcohol-Induced Brain Mitochondrial Dysfunction in Rats

  2011cites this paper
• Low intensity light stimulates nitrite-dependent nitric oxide synthesis but not oxygen consumption by cytochrome c oxidase: Implications for phototherapy.

  2011cites this paper
• NO and O2 reactivities of synthetic functional models of nitric oxide reductase and cytochrome c oxidase.

  2011cites this paper
• A Computational flow model of oxygen and nitric oxide transport & reactions and the relation with glaucoma

  2011cites this paper
• Mechanistic studies of NO reduction in dinuclear metalloproteins

  2011cites this paper
• The anoxic plant mitochondrion as a nitrite: NO reductase.

  2011influential citation
• Electronic structure and dynamics of nitrosyl porphyrins.

  2010cites this paper
• Bioinspired heme, heme/nonheme diiron, heme/copper, and inorganic NOx chemistry: *NO((g)) oxidation, peroxynitrite-metal chemistry, and *NO((g)) reductive coupling.

  2010cites this paper
• GDP and carboxyatractylate inhibit 4-hydroxynonenal-activated proton conductance to differing degrees in mitochondria from skeletal muscle and heart.

  2010cites this paper
• Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices.

  2010cites this paper
• Myoglobin strikes back

  2010cites this paper
• Anoxic nitric oxide cycling in plants: participating reactions and possible mechanisms.

  2010cites this paper
• Organizzazione strutturale della catena respiratoria mitocondriale

  2010cites this paper
• Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells.

  2010cites this paper
• X-ray structure of the NO-bound Cu(B) in bovine cytochrome c oxidase.

  2010cites this paper
• Recent applications of a synthetic model of cytochrome c oxidase: beyond functional modeling.

  2010cites this paper
• Inactivation of cytochrome c oxidase by mutant SOD1s in mouse motoneuronal NSC‐34 cells is independent from copper availability but is because of nitric oxide

  2010cites this paper
• Mechanisms of the Beneficial Actions of Ischemic Preconditioning on Subcellular Remodeling in Ischemic-Reperfused Heart

  2010cites this paper
• Carbon monoxide and nitrogen monoxide ligand dynamics in synthetic heme and heme-copper complex systems.

  2009cites this paper
• Plant mitochondrial function during anaerobiosis.

  2009cites this paper
• Cardioprotection by metabolic shut-down and gradual wake-up.

  2009cites this paper
• Nitric oxide suppresses transforming growth factor‐β1–induced epithelial‐to‐mesenchymal transition and apoptosis in mouse hepatocytes

  2009cites this paper
• Interaction of nitric oxide with the activity of cytosolic NADH/cytochrome c electron transport system.

  2009cites this paper
• The mechanism of action of PA-824

  2009cites this paper
• Mitochondrial nitrite reduction coupled to soluble guanylate cyclase activation: lack of evidence for a role in the bioactivation of nitroglycerin.

  2009cites this paper
• Changes in cytochrome c oxidase and NO in rat lung mitochondria following iron overload

  2009cites this paper
• O2 reduction by a functional heme/nonheme bis-iron NOR model complex

  2009cites this paper
• Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins

  2009cites this paper
• Mitochondrial generation of free radicals and hypoxic signaling.

  2009cites this paper
• Inhibition of electrocatalytic O(2) reduction of functional CcO models by competitive, non-competitive, and mixed inhibitors.

  2009cites this paper
• Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols

  2008cites this paper
• Interaction of nitric oxide with a functional model of cytochrome c oxidase

  2008cites this paper
• Caractérisation structurale et fonctionnelle d'oxyde nitrique synthases bactériennes

  2007cites this paper
• Spectroscopic characterization of heme iron-nitrosyl species and their role in NO reductase mechanisms in diiron proteins.

  2007cites this paper
• Relative sensitivity of soluble guanylate cyclase and mitochondrial respiration to endogenous nitric oxide at physiological oxygen concentration.

  2007influential citation
• Redox control of fast ligand dissociation from Escherichia coli cytochrome bd.

  2007cites this paper