Estudio prospectivo y randomizado de suplementación de hierro temprana versus tardía en niños con peso al nacer menor de 1.301 g

Objetivo: Determinar si la suplementacion temprana de hierro disminuye la necesidad, el numero y volumen de globulos rojos transfundidos, en relacion a la suplementacion tardia de hierro en ninos con peso de nacimiento menor a 1.301 g. Pacientes y Metodo: Recien nacidos de muy bajo peso (RNMPN) fueron randomi-zados a recibir suplementacion temprana de hierro de 3 mg/kg/dia, tan pronto estaban tolerando alimentacion enteral de 100 ml/kg/dia, o a los 61 dias de vida como suplementacion tardia. Se midio niveles de hemoglobina al inicio de la suplementacion temprana de hierro y a los 2 meses de vida. La transfusion de globulos rojos fue restringida de acuerdo a las guias de transfusion y no se administro eritropoyetina. Resultados: No hay diferencias en el numero de transfusiones de globulos rojos entre los grupos y en relacion a las morbilidades asociadas con la prematuridad no habria diferencias significativas. Conclusiones: La suplementacion temprana de hierro cuando el nino este tolerando 100 ml/kg/dia de leche, no disminuiria la incidencia de las transfusiones de globulos rojos en relacion al inicio tardio de hierro a los 61 dias de vida y probablemente sea segura en los ninos menores de 1.301 g.

• Publication year

  2013

• Venue

  Revista chilena de pediatría

• Publication date

  2013-07-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.4067/S0370-41062013000400003
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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