Gadolinium-containing magnetic resonance contrast media: investigation on the possible transchelation of Gd³⁺ to the glycosaminoglycan heparin.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Contrast Media & Molecular Imaging

• Publication date

  2013-03-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/cmmi.1500PMID 23281283
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The role of phosphate on Omniscan® dechelation: an in vitro relaxivity study at pH 7

  2011cited by this paper
• Erratum to: The role of phosphate on Omniscan® dechelation: an in vitro relaxivity study at pH 7

  2011cited by this paper
• Incidence of nephrogenic systemic fibrosis after adoption of restrictive gadolinium-based contrast agent guidelines.

  2011cited by this paper
• Pathomechanisms of nephrogenic systemic fibrosis: new insights

  2011cited by this paper
• Quantification of gadolinium in fresh skin and serum samples from patients with nephrogenic systemic fibrosis.

  2011cited by this paper
• Synchrotron X‐ray analyses demonstrate phosphate‐bound gadolinium in skin in nephrogenic systemic fibrosis

  2010cited by this paper
• How to measure the transmetallation of a gadolinium complex.

  2010cited by this paper
• Improved Characterization of Focal Liver Lesions With Liver-Specific Gadoxetic Acid Disodium-Enhanced Magnetic Resonance Imaging: A Multicenter Phase 3 Clinical Trial

  2010cited by this paper
• Gadolinium deposition in nephrogenic systemic fibrosis: an examination of tissue using synchrotron x-ray fluorescence spectroscopy.

  2010cited by this paper
• Gadolinium‐Induced Nephrogenic Systemic Fibrosis Is Associated with Insoluble Gd Deposits in Tissues: In Vivo Transmetallation Confirmed by Microanalysis

  2009cited by this paper
• Comparison of 1.0 M Gadobutrol and 0.5 M Gadopentetate Dimeglumine-Enhanced Magnetic Resonance Imaging in Five Hundred Seventy-Two Patients With Known or Suspected Liver Lesions: Results of a Multicenter, Double-Blind, Interindividual, Randomized Clinical Phase-III Trial

  2009cited by this paper
• Evaluating the role of zinc in the occurrence of fibrosis of the skin: A preclinical study

  2009cited by this paper
• Long-term retention of gadolinium in the skin of rodents following the administration of gadolinium-based contrast agents

  2009cited by this paper
• Role of thermodynamic and kinetic parameters in gadolinium chelate stability

  2009cited by this paper
• Gadolinium‐based contrast agents and NSF: Evidence from animal experience

  2009cited by this paper
• Biodistribution of gadolinium‐based contrast agents, including gadolinium deposition

  2009cited by this paper
• Nephrogenic systemic fibrosis after gadopentetate dimeglumine exposure: case series of 36 patients.

  2009cited by this paper
• Stability of Gadolinium-Based Magnetic Resonance Imaging Contrast Agents in Human Serum at 37°C

  2008cited by this paper
• Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions

  2008cited by this paper
• Efficiency, thermodynamic and kinetic stability of marketed gadolinium chelates and their possible clinical consequences: a critical review

  2008cited by this paper
• A Preclinical Study to Investigate the Development of Nephrogenic Systemic Fibrosis: A Possible Role for Gadolinium-Based Contrast Media

  2008cited by this paper
• Strong association between the use of gadolinium‐based contrast agents with nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis

  2007cited by this paper
• Clinical Safety and Diagnostic Value of the Gadolinium Chelate Gadoterate Meglumine (Gd-DOTA)

  2007cited by this paper
• Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents.

  2006cited by this paper
• Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation

  2006cited by this paper
• Assessment of Utilization and Pharmacovigilance Based on Spontaneous Adverse Event Reporting of Gadopentetate Dimeglumine as a Magnetic Resonance Contrast Agent After 45 Million Administrations and 15 Years of Clinical Use

  2006cited by this paper
• A Summary of Safety of Gadofosveset (MS-325) at 0.03 mmol/kg Body Weight Dose: Phase II and Phase III Clinical Trials Data

  2006cited by this paper
• Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?

  2006cited by this paper
• Scleromyxedema‐like lesions of patients in renal failure contain hyaluronan: a possible pathophysiological mechanism

  2005cited by this paper
• Human comparative study of zinc and copper excretion via urine after administration of magnetic resonance imaging contrast agents.

  2005cited by this paper
• Comparison of Magnetic Properties of MRI Contrast Media Solutions at Different Magnetic Field Strengths

  2005cited by this paper
• Probing the interaction of the biotin-avidin complex with the relaxivity of biotinylated Gd-DTPA.

  2004cited by this paper
• Thermosensitive lanthanide complexes of hyaluronan.

  2002cited by this paper
• The OptiMARK clinical development program: Summary of safety data

  2002cited by this paper
• Gadolinium diffusion into orbital vitreous and aqueous humor, perivascular space, and ventricles in patients with chronic renal disease.

  2002cited by this paper
• Relaxivity and diffusion of gadolinium agents in cartilage

  2002cited by this paper
• Stability of MRI Paramagnetic Contrast Media: A Proton Relaxometric Protocol for Transmetallation Assessment

  2001cited by this paper
• Safety assessment of gadobenate dimeglumine (MultiHance®): Extended clinical experience from phase I studies to post‐marketing surveillance

  2001cited by this paper
• The rates of the exchange reactions between [Gd(DTPA)]2- and the endogenous ions Cu2+ and Zn2+: a kinetic model for the prediction of the in vivo stability of [Gd(DTPA)]2-, used as a contrast agent in magnetic resonance imaging.

  2000cited by this paper
• Scleromyxoedema-like cutaneous diseases in renal-dialysis patients.

  2000cited by this paper
• Magnetic resonance angiography with gadomer-17. An animal study original investigation.

  1998cited by this paper
• Worldwide clinical safety assessment of gadoteridol injection: an update

  1997cited by this paper
• Preclinical evaluation of the pharmacokinetics, biodistribution, and elimination of MS-325, a blood pool agent for magnetic resonance imaging.

  1997cited by this paper
• Evaluation of the clinical safety of gadodiamide injection, a new nonionic MRI contrast medium for the central nervous system: a European perspective

  1996cited by this paper
• Serum hyaluronan concentrations predict survival in patients with chronic renal failure on maintenance haemodialysis.

  1996cited by this paper
• Comparative transmetallation kinetics and thermodynamic stability of gadolinium-DTPA bis-glucosamide and other magnetic resonance imaging contrast media.

  1996cited by this paper
• Human in vivo comparative study of zinc and copper transmetallation after administration of magnetic resonance imaging contrast agents.

  1996cited by this paper
• Supramolecular organization of extracellular matrix glycosaminoglycans, in vitro and in the tissues

  1992cited by this paper
• Quantification of dechelation of gadopentetate dimeglumine in rats.

  1992cited by this paper
• A new lipophilic gadolinium chelate as a tissue‐specific contrast medium for MRI

  1991cited by this paper
• Comparison of Gd-BOPTA with Gd-DTPA in MR imaging of rat liver.

  1990cited by this paper
• Evaluation of Gd-DTPA-labeled dextran as an intravascular MR contrast agent: imaging characteristics in normal rat tissues.

  1990cited by this paper
• Albumin labeled with Gd-DTPA: an intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterization.

  1987cited by this paper
• Albumin labeled with Gd-DTPA. An intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterization.

  1987cited by this paper
• Circulating hyaluronate. A potential marker of altered metabolism of the connective tissue in uremia.

  1987cited by this paper
• The molecular weight of hyaluronate in the aqueous humour and vitreous body of rabbit and cattle eyes.

  1983cited by this paper
• Dermatan sulfate: molecular conformations and interactions in the condensed state.

  1983cited by this paper
• Mechanism of tumor and liver concentration of 111In and 169Yb: 111In and 169Yb binding substances in tumor tissues and liver

  1982cited by this paper
• The glycosaminoglycans (mucopolysaccharides) in plasma in patients with renal insufficiency.

  1977cited by this paper
• Solubilization of cartilage protein--polysaccharide with lanthanum chloride.

  1972cited by this paper
• Zinc concentration in human tissues.

  1972cited by this paper
• THE USE OF LANTHANUM TO STUDY THE DEGRADATION OF A PROTEINPOLYSACCHARIDE FROM CARTILAGE.

  1964cited by this paper
• The concentrations of cobalt, copper, iron and zinc in some normal human tissues as determined by neutron-activation analysis.

  1964cited by this paper

• Glycan-Induced Transchelation of Gadolinium from Magnetic Resonance Imaging Contrast Agent-Complexes

  2025cites this paper
• Fate of gadolinium in inflamed mouse brain: Release and phosphate interaction post-contrast agent administration

  2025influential citation
• Gadolinium toxicity: mechanisms, clinical manifestations, and nanoparticle role

  2025influential citation
• Gadolinium Deposition in Bone Tissues After Contrast-enhanced Magnetic Resonance Imaging

  2025cites this paper
• Quantitative Analysis of Gadolinium Deposits in Liver Tissue of Patients After Single or Multiple Gadolinium-based Contrast Agent Application.

  2025cites this paper
• Generative Adversarial Network Based Contrast Enhancement: Synthetic Contrast Brain Magnetic Resonance Imaging.

  2024cites this paper
• Effects of Gadolinium Retention in the Brains of Type 2 Diabetic Rats after Repeated Administration of Gadolinium‐Based MRI Contrast Agents on Neurobiology and NLRP3 Inflammasome Activation

  2024cites this paper
• Uremic Toxin-Induced Exosome-like Extracellular Vesicles Contain Enhanced Levels of Sulfated Glycosaminoglycans which Facilitate the Interaction with Very Small Superparamagnetic Iron Oxide Particles

  2023cites this paper
• The electrostatic confinement of aquated monocationic Gd(III) complex-molecules within the inner core of porous silica nanoparticles creates a highly efficient T1 contrast agent for magnetic resonance imaging.

  2022cites this paper
• Investigating the Role of Sulfate Groups for the Binding of Gd3+ Ions to Glycosaminoglycans with NMR Relaxometry

  2022cites this paper
• Different Impact of Gadopentetate and Gadobutrol on Inflammation-Promoted Retention and Toxicity of Gadolinium Within the Mouse Brain

  2022cites this paper
• Speciation Analysis of Gadolinium in the Water-Insoluble Rat Brain Fraction After Administration of Gadolinium-Based Contrast Agents

  2021cites this paper
• An NMR relaxometry approach for quantitative investigation of the transchelation of gadolinium ions from GBCAs to a competing macromolecular chelator

  2021cites this paper
• Retention of Gadolinium in Brain Parenchyma: Pathways for Speciation, Access, and Distribution. A Critical Review

  2020cites this paper
• Microdistribution of Magnetic Resonance Imaging Contrast Agents in Atherosclerotic Plaques Determined by LA-ICP-MS and SR-μXRF Imaging

  2020cites this paper
• Rare earth metal–organic frameworks (RE-MOFs): Synthesis, properties, and biomedical applications

  2020cites this paper
• Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats

  2020cites this paper
• Gadolinium Complexes as Contrast Agent for Cellular NMR Spectroscopy

  2020cites this paper
• UV-triggered photoinsertion of contrast agent onto polymer surfaces for in vivo MRI-visible medical devices

  2019cites this paper
• Physicochemical and Pharmacokinetic Profiles of Gadopiclenol

  2019cites this paper
• Distribution of Gadolinium in Rat Heart Studied by Fast Field Cycling Relaxometry and Imaging SIMS

  2019cites this paper
• Increased Retention of Gadolinium in the Inflamed Brain After Repeated Administration of Gadopentetate Dimeglumine: A Proof-of-Concept Study in Mice Combining ICP-MS and Micro- and Nano-SR-XRF.

  2019cites this paper
• Chemical Insights into the Issues of Gd Retention in the Brain and Other Tissues Upon the Administration of Gd-Containing MRI Contrast Agents

  2018cites this paper
• Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals

  2018cites this paper
• Dechelation (Transmetalation): Consequences and Safety Concerns With the Linear Gadolinium-Based Contrast Agents, In View of Recent Health Care Rulings by the EMA (Europe), FDA (United States), and PMDA (Japan)

  2018cites this paper
• Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?

  2018cites this paper
• The Extracellular Matrix as a Target for Biophysical and Molecular Magnetic Resonance Imaging

  2018cites this paper
• Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents

  2017cites this paper
• Quantification and Assessment of the Chemical Form of Residual Gadolinium in the Brain After Repeated Administration of Gadolinium-Based Contrast Agents

  2017cites this paper
• Assessment of active and inactive sacroiliitis in patients with ankylosing spondylitis using quantitative dynamic contrast‐enhanced MRI

  2017cites this paper
• Advanced contrasts for vascular MRI

  2017cites this paper
• Nanoparticle-based highly sensitive MRI contrast agents with enhanced relaxivity in reductive milieu.

  2016cites this paper
• Stimuli-responsive amphiphilic peptides for biomedical applications

  2016cites this paper
• Stability of gadolinium-based contrast agents in the presence of zinc and calcium ions in different media

  2016cites this paper
• Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms

  2016cites this paper
• Die multiparametrische Magnetresonanztomographie in Detektion und bildgeführter Biopsie des Prostatakarzinoms

  2015cites this paper
• Magnetresonanztomografie der Sakroiliitis bei Patienten mit Spondyloarthritis: Korrelation mit Anatomie und Histologie

  2014cites this paper
• The role of gadolinium chelates in the mechanism of nephrogenic systemic fibrosis: A critical update

  2014influential citation
• Magnetic Resonance Imaging of Sacroiliitis in Patients with Spondyloarthritis: Correlation with Anatomy and Histology

  2013cites this paper