Frequent Deletion and Methylation in SH3GL2 and CDKN2A Loci are Associated with Early- and Late-onset Breast Carcinoma

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Annals of Surgical Oncology

• Publication date

  2008-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1245/s10434-007-9790-0PMID 18239974
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Deletions in chromosome 4 differentially associated with the development of cervical cancer: evidence of slit2 as a candidate tumor suppressor gene

  2007cited by this paper
• Study of the SH3‐domain GRB2‐like 2 gene expression in laryngeal carcinoma

  2007cited by this paper
• Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer

  2006cited by this paper
• Breast cancer in young Asian women: Study on survival

  2005cited by this paper
• Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.

  2005cited by this paper
• [Promoter methylation profile in breast cancer].

  2004cited by this paper
• Patrón de metilación génico en el cáncer de mama

  2004cited by this paper
• Analysis of Different Deleted Regions in Chromosome 11 and Their Interrelations in Early- and Late-Onset Breast Tumors: Association with Cyclin D1 Amplification and Survival

  2004cited by this paper
• Differential alterations of the genes in the CDKN2A-CCND1-CDK4-RB1 pathway are associated with the development of head and neck squamous cell carcinoma in Indian patients

  2003cited by this paper
• Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms

  2003cited by this paper
• Mechanisms controlling EGF receptor endocytosis and degradation.

  2003cited by this paper
• Deletion mapping of chromosome 1 in early onset and late onset breast tumors--a comparative study in eastern India.

  2003cited by this paper
• Cancer patterns in eastern India: The first report of the Kolkata cancer registry

  2002cited by this paper
• Germline mutation of ARF in a melanoma kindred.

  2002cited by this paper
• Two regions of deletion in 9p22- p24 in neuroblastoma are frequently observed in favorable tumors.

  2002cited by this paper
• p16 and p53 Protein expression as prognostic indicators of survival and disease recurrence from head and neck cancer.

  2002cited by this paper
• Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization

  2002cited by this paper
• Mapping of the candidate tumor suppressor genes' loci on human chromosome 3 in head and neck squamous cell carcinoma of an Indian patient population.

  2002cited by this paper
• Genetic and epigenetic alterations of the INK4a–ARF pathway in cholangiocarcinoma

  2002cited by this paper
• Methylation and silencing of the retinoic acid receptor-β2 gene in cervical cancer

  2002cited by this paper
• Evidence for three tumor suppressor loci on chromosome 9p involved in melanoma development.

  2001cited by this paper
• Overexpression of the p16 Cell Cycle Inhibitor in Breast Cancer is Associated with a More Malignant Phenotype

  2001cited by this paper
• Analysis of genetic and epigenetic processes that influence p14ARF expression in breast cancer

  2001cited by this paper
• Molecular analysis of the INK4A and INK4B gene loci in human breast cancer cell lines and primary carcinomas.

  2001cited by this paper
• Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities.

  2000cited by this paper
• Quality of life in patients with early and advanced carcinoma of the breast.

  2000cited by this paper
• The INK4A/ARF locus and its two gene products.

  1999cited by this paper
• Two regions of deletion in 9p23-24 in sporadic breast cancer.

  1999cited by this paper
• TNM Classification of Malignant Tumors

  1998cited by this paper
• Loss of heterozygosity at chromosome 9p in ductal carcinoma in situ and invasive carcinoma of the breast.

  1998cited by this paper
• Prognostic importance of p15INK4B and p16INK4 gene inactivation in childhood acute lymphocytic leukemia.

  1996influential reference
• Frequent allele loss on 9p21–22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer

  1996cited by this paper
• Preferential loss of expression of p16(INK4a) rather than p19(ARF) in breast cancer.

  1996cited by this paper
• Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.

  1996cited by this paper
• Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells.

  1995cited by this paper
• Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

  1995cited by this paper
• Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions

  1995cited by this paper
• Analysis of p16 gene deletion and point mutation in breast carcinoma.

  1995cited by this paper
• Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas.

  1994influential reference
• Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers.

  1992cited by this paper

• DNA Methylation and Transcript Variant Analysis of CDKN2A Exon 2 Despite High Sequence Identity with CDKN2B Exon 2

  2025cites this paper
• Bending the boundaries: the many facets of endophilin-As from membrane dynamics to disease

  2025cites this paper
• CDKN2A promoter methylation enhances self-renewal of glioblastoma stem cells and confers resistance to carmustine

  2024cites this paper
• SH3GL2 and MMP17 as lung adenocarcinoma biomarkers: a machine-learning based approach

  2024cites this paper
• Biology of endophilin and it’s role in disease

  2023cites this paper
• Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma

  2022cites this paper
• Methylation Profiling of Specific Genes in Ependymomas

  2021cites this paper
• Impact of Endocytosis Mechanisms for the Receptors Targeted by the Currently Approved Antibody-Drug Conjugates (ADCs)—A Necessity for Future ADC Research and Development

  2021cites this paper
• Impact of Endocytosis Mechanisms for the Receptors Targeted by the Currently Approved ADCs—A Necessity for Future ADC Research and Development

  2021cites this paper
• Genistein inhibited the proliferation of kidney cancer cells via CDKN2a hypomethylation: role of abnormal apoptosis

  2020cites this paper
• Reduction of nuclear Y654‐p‐β‐catenin expression through SH3GL2‐meditated downregulation of EGFR in chemotolerance TNBC: Clinical and prognostic importance

  2020cites this paper
• Over-expression of HDAC8 down-regulate CDKN2A is associated with worse prognosis of esophageal squamous cell carcinoma

  2020cites this paper
• Quantitative Proteomics Reveals Global Reduction of Endocytic Machinery Components in Gliomas

  2019cites this paper
• Quantitative proteomics reveals reduction of endocytic machinery components in gliomas

  2019cites this paper
• Determinants of p14/ARF methylation in healthy females: association with reproductive and non-reproductive risk factors of breast cancer

  2019cites this paper
• Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles

  2019cites this paper
• Association of cyclin‐dependent kinase inhibitor 2A/B with increased risk of developing breast cancer

  2019cites this paper
• Induction of HRR genes and inhibition of DNMT1 is associated with anthracycline anti-tumor antibiotic-tolerant breast carcinoma cells

  2018cites this paper
• Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

  2018cites this paper
• Atlas of Genetics and Cytogenetics in Oncology and Haematology FANCC ( Fanconi anaemia complementation group C )

  2018cites this paper
• Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis.

  2018cites this paper
• Hypomethylation of mismatch repair genes MLH1 and MSH2 is associated with chemotolerance of breast carcinoma: Clinical significance

  2018cites this paper
• Frequent alterations of homologous recombination repair pathway in primary and chemotolerant breast carcinomas: clinical importance.

  2017cites this paper
• Estudo da via PI3k/AKT e da perda de Heterozigosidade do gene supressor tumoral Pten em lesões potencialmente malignas e Carcinoma epidermoide oral

  2017cites this paper
• Loss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling

  2017cites this paper
• Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients

  2017cites this paper
• CDKN2A methylation in esophageal cancer: a meta-analysis

  2017cites this paper
• p16 overexpression and 9p21 deletion are linked to unfavorable tumor phenotype in breast cancer

  2016cites this paper
• Mitochondrial Reprogramming Regulates Breast Cancer Progression

  2016cites this paper
• Albumin Carriers for Cancer Theranostics: A Conventional Platform with New Promise

  2016cites this paper
• Frequent inactivation of MCC/CTNNBIP1 and overexpression of phospho-beta-catenin(Y654) are associated with breast carcinoma: Clinical and prognostic significance.

  2016cites this paper
• The stem cell renewal and DNA damage response pathways are frequently altered in fibroepithelial tumors of breast in Indian patients.

  2016cites this paper
• Aberrant promoter methylation of SH3GL2 gene in vulvar squamous cell carcinoma correlates with clinicopathological characteristics and HPV infection status.

  2015cites this paper
• Distinct Functions of Endophilin Isoforms in Synaptic Vesicle Endocytosis

  2015cites this paper
• Clinical implications of β-catenin protein expression in breast cancer.

  2015cites this paper
• SNP rs1049430 in the 3'-UTR of SH3GL2 regulates its expression: Clinical and prognostic implications in head and neck squamous cell carcinoma.

  2015cites this paper
• Molecular mechanisms of squamous differentiation in urothelial cell carcinoma: a paradigm for molecular subtyping of urothelial cell carcinoma of the bladder.

  2015cites this paper
• MiR-330-Mediated Regulation of SH3GL2 Expression Enhances Malignant Behaviors of Glioblastoma Stem Cells by Activating ERK and PI3K/AKT Signaling Pathways

  2014cites this paper
• Determination of the DNA Methylation Status of Breast Cancer-Related Genes in Vivo and in Vitro by High Resolution Melting Analysis

  2013cites this paper
• Epigenetic regulation of the X‐linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma

  2013cites this paper
• Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.

  2013cites this paper
• Overexpression of EGFR in Head and Neck Squamous Cell Carcinoma Is Associated with Inactivation of SH3GL2 and CDC25A Genes

  2013cites this paper
• Frequent Alterations of MCPH1 and ATM are Associated with Primary Breast Carcinoma: Clinical and Prognostic Implications

  2013cites this paper
• Subtype‐specific alterations of the Wnt signaling pathway in breast cancer: Clinical and prognostic significance

  2012cites this paper
• Estudo da perda de heterozigosidade de genes supressores de tumor em tumores odontogênicos mistos

  2012cites this paper
• Reduced expression of LIMD1 in ulcerative oral epithelium associated with tobacco and areca nut.

  2012cites this paper
• Loss of heterozygosity (LOH) in tumour suppressor genes in benign and malignant mixed odontogenic tumours.

  2012cites this paper
• SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling

  2012cites this paper
• MicroRNA-330 Is an Oncogenic Factor in Glioblastoma Cells by Regulating SH3GL2 Gene

  2012cites this paper
• The Structure and Function of Endophilin Proteins

  2011cites this paper
• Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1‐24.2 region in breast carcinoma: Clinical and prognostic implications

  2011cites this paper
• Association of APC and MCC Polymorphisms with Increased Breast Cancer Risk in an Indian Population

  2011cites this paper
• SH3GL2 (SH3-domain GRB2-like 2)

  2011cites this paper
• Let's go bananas: revisiting the endocytic BAR code

  2011cites this paper
• Assoziation methylierter Gene im Blut von Mammakarzinompatientinnen mit dem Auftreten zirkulierender Tumorzellen und dem

  2010cites this paper
• Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

  2008cites this paper
• Frequent alterations of hMLH1 and RBSP3/HYA22 at chromosomal 3p22.3 region in early and late‐onset breast carcinoma: clinical and prognostic significance

  2008cites this paper
• Modification of second cancer risk after malignant melanoma by parental history of cancer

  2008influential citation