Updates in spindle cell/pleomorphic lipomas.

Benjamin J. Van Treeck,K. Fritchie

Published 2019 in Seminars in diagnostic pathology

ABSTRACT

Spindle cell/pleomorphic lipomas are benign lipomatous neoplasms that show loss of RB1 and classically harbor components of mature adipose tissue, bland spindled cells and ropy collagen. This review highlights the clinicopathologic features and morphologic spectrum of spindle cell/pleomorphic lipoma, discusses an updated differential diagnosis, and provides a practical diagnostic strategy for spindle cell/pleomorphic lipomas with atypical clinical presentations.

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