Luminal flow induces eNOS activation and translocation in the rat thick ascending limb. II. Role of PI3-kinase and Hsp90.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  AJP - Renal Physiology

• Publication date

  2004-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPRENAL.00383.2003PMID 15100099
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• High-Salt Diet Increases Sensitivity to NO and eNOS Expression But Not NO Production in THALs

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  2002influential reference
• NOSTRIN: A protein modulating nitric oxide release and subcellular distribution of endothelial nitric oxide synthase

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• Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase.

  1999cited by this paper
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• Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase.

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  1999influential reference
• In Situ Flow Activates Endothelial Nitric Oxide Synthase in Luminal Caveolae of Endothelium with Rapid Caveolin Dissociation and Calmodulin Association*

  1998cited by this paper
• Receptor-regulated Translocation of Endothelial Nitric-oxide Synthase*

  1998cited by this paper
• Dynamic activation of endothelial nitric oxide synthase by Hsp90

  1998cited by this paper
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  1998cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Wortmannin, an Inhibitor of Phosphoinositide 3-Kinase, Inhibits Transcytosis in Polarized Epithelial Cells (*)

  1995cited by this paper
• Shear Stress‐Induced Release of Nitric Oxide From Endothelial Cells Grown on Beads

  1991influential reference

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