The localization of mercury and metallothionein in the cerebellum of rats experimentally exposed to methylmercury

No abstract is available for this paper.

• Publication year

  1994

• Venue

  The Histochemical Journal

• Publication date

  1994-02-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1007/BF00157965PMID 8150662
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitative immunohistochemistry of metallothionein in rat placenta

  2004cited by this paper
• Immunohistochemical localization of metallothionein in the eye of rats

  2004cited by this paper
• Distribution of metallothionein in the human central nervous system

  1993cited by this paper
• Localization of metallothionein in the brain of rat and mouse.

  1992cited by this paper
• IMMUNOHISTOCHEMICAL LOCALIZATION OF METALLOTHIONEIN IN ORGANS OF RATS TREATED WITH EITHER CADMIUM, INORGANIC OR ORGANIC MERCURIALS

  1991cited by this paper
• Metallothionein-I induction by stress in specific brain areas

  1991cited by this paper
• [44] Detection of metallothionein in brain

  1991cited by this paper
• Immunohistochemical detection of metallothionein.

  1991cited by this paper
• Localization of mercury in CNS of the rat. III. Oral administration of methylmercuric chloride (CH3HgCl).

  1991cited by this paper
• An integrated study of the morphological and gross-elemental consequences of methyl mercury intoxication in rats, with particular attention on the cerebellum.

  1991cited by this paper
• Detection of metallothionein in brain.

  1991cited by this paper
• Bacterial endotoxin-induced expression of metallothionein genes in rat brain, as revealed by in situ hybridization.

  1991cited by this paper
• Metallothioneins and other zinc-binding proteins in brain.

  1991cited by this paper
• Glial immunoreactivity for metallothionein in the rat brain

  1991cited by this paper
• Localization of mercury in CNS of the rat. II. Intraperitoneal injection of methylmercuric chloride (CH3HgCl) and mercuric chloride (HgCl2).

  1990cited by this paper
• Localization of metallothionein in the genital organs of the male rat.

  1990cited by this paper
• A new perspective of radiation protection by metallothionein induction.

  1988cited by this paper
• Suppression of gastric ulcer induced by stress and HCL-ethanol by intravenously administered metallothionein-II.

  1988cited by this paper
• The toxicity, distribution and elimination of methylmercury in mice following intracerebral injection.

  1987cited by this paper
• Histochemical demonstration of two mercury pools in trout tissues: mercury in kidney and liver after mercuric chloride exposure.

  1986cited by this paper
• Biochemical characterization of a metallothionein-like protein in rat brain

  1986cited by this paper
• Simultaneous ultrastructural demonstration of heavy metals (silver, mercury) and acid phosphatase

  1986cited by this paper
• Metallothionein.

  1986cited by this paper
• CHANGES IN THE DISTRIBUTION OF HISTOCHEMICALLY LOCALIZED MERCURY IN THE CNS AND IN TISSUE LEVELS OF ORGANIC AND INORGANIC MERCURY DURING THE DEVELOPMENT OF INTOXICATION IN METHYLMERCURY TREATED RATS

  1985cited by this paper
• Free radicals in biology and medicine

  1985cited by this paper
• Interaction of alkylmercuric compounds with sodium selenite. III. Biotransformation, levels of metallothioneinlike proteins and endogenous copper in some tissues of rats exposed to methyl or ethylmercuric chloride with and without sodium selenite.

  1985cited by this paper
• Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals.

  1985cited by this paper
• Non-deleterious dinitrophenyl (DNP) hapten labelling of antibody protein. Preparation and properties of some short-chain DNP imidoesters.

  1984cited by this paper
• Metallothionein--a unique protein with multiple detoxifying properties?

  1984cited by this paper
• Changing Metal Cycles and Human Health

  1984cited by this paper
• Functions of metallothionein.

  1982cited by this paper
• Early morphological changes in rat cerebellum caused by a single dose of methylmercury

  1981cited by this paper
• Use of monoclonal antihapten antibodies for immunolocalisation of tissue antigens

  1981cited by this paper
• CELLULAR DISCRIMINATION PROCESSES IN METAL ACCUMULATING CELLS

  1981cited by this paper
• Histochemical demonstration of mercury induced changes in rat neurons

  1979cited by this paper
• Postexposure preventive treatment of methylmercury intoxication in rats with dimercaptosuccinic acid.

  1978cited by this paper
• The influence of selenium on the level of mercury and metallothionein in rat kidneys in prolonged exposure to different mercury compounds

  1978cited by this paper
• Neurotoxic effects of mercury--a review.

  1977cited by this paper
• Ultrastructural changes in the nervous system of rabbits poisoned with methyl mercury.

  1977cited by this paper
• Cerebellar Cortex

  1974cited by this paper
• CEREBELLAR CORTEX, CYTOLOGY AND ORGANIZATION

  1974cited by this paper
• Mercury binding in the kidney and liver of rats repeatedly exposed to mercuric chloride: induction of metallothionein by mercury and cadmium.

  1974cited by this paper
• Electron microscopic histochemical study on the localization and distribution of mercury in the nervous system after mercury intoxication.

  1972cited by this paper
• THE PATHOGENETIC MECHANISMS OF EXPERIMENTAL POISONING BY MERCURY VAPOR.

  1965cited by this paper

• Pathogenesis of selective damage of granule cell layer in cerebellum of rats exposed to methylmercury.

  2023cites this paper
• Astrocyte-Like Cells Transcriptome Changes After Exposure to a Low and Non-cytotoxic MeHg Concentration

  2022cites this paper
• First record on mercury accumulation in mice brain living in active volcanic environments: a cytochemical approach

  2020cites this paper
• Acute neurotoxicant exposure induces hyperexcitability in mouse lumbar spinal motor neurons.

  2020cites this paper
• Rethinking mercury: the role of selenium in the pathophysiology of mercury toxicity

  2018cites this paper
• Effects of methylmercury on spinal cord afferents and efferents-A review.

  2017cites this paper
• Die Toxikologie des Quecksilbers und seiner Verbindungen

  2014cites this paper
• Methylmercury impairs motor function in early development and induces oxidative stress in cerebellar granule cells.

  2013cites this paper
• Evidences for a role of glutathione peroxidase 4 (GPx4) in methylmercury induced neurotoxicity in vivo.

  2012cites this paper
• The toxicology of mercury and its compounds.

  2012cites this paper
• Methylmercury Neurotoxicity: Why Are some Cells more Vulnerable than Others?

  2012cites this paper
• Efeito do difenil disseleneto sobre o déficit energético e alterações na morfologia e conteúdo mitocondriais induzidos pelo metilmercúrio no córtex cerebral de camundongos

  2012cites this paper
• Ca2+ entry pathways in mouse spinal motor neurons in culture following in vitro exposure to methylmercury.

  2011cites this paper
• Induction of metallothionein in mouse cerebellum and cerebrum with low-dose thimerosal injection

  2010cites this paper
• Expression of metallothionein mRNAs on mouse cerebellum microglia cells by thimerosal and its metabolites.

  2009cites this paper
• Cerebellum cholinergic muscarinic receptor (subtype-2 and -3) and cytoarchitecture after developmental exposure to methylmercury: an immunohistochemical study in rat.

  2008cites this paper
• Metallothionein in the central nervous system: Roles in protection, regeneration and cognition.

  2008cites this paper
• Cellular and molecular mechanisms behind methylmercury-induced neurotoxicity.

  2008influential citation
• Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.

  2008cites this paper
• Comparative study of activities in reactive oxygen species production/defense system in mitochondria of rat brain and liver, and their susceptibility to methylmercury toxicity

  2007cites this paper
• Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress.

  2007cites this paper
• Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity.

  2007cites this paper
• Methylmercury-Induced Increase of Intracellular Ca2+ Increases Spontaneous Synaptic Current Frequency in Rat Cerebellar Slices

  2007cites this paper
• Heavy metals affect the coelomocyte-bacteria balance in earthworms: environmental interactions between abiotic and biotic stressors.

  2006cites this paper
• Metallothioneins: Mercury Species-Specific Induction and Their Potential Role in Attenuating Neurotoxicity

  2006cites this paper
• Acute cytotoxic effects of mercuric compounds in cultured astrocytes prepared from cerebral hemisphere and cerebellum of newborn rats.

  2005cites this paper
• Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction?

  2005cites this paper
• Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+.

  2005cites this paper
• Inwardly rectifying and voltage-gated outward potassium channels exhibit low sensitivity to methylmercury.

  2005cites this paper
• Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury.

  2005cites this paper
• Disruption of intraneuronal divalent cation regulation by methylmercury: are specific targets involved in altered neuronal development and cytotoxicity in methylmercury poisoning?

  2004cites this paper
• Astrocyte Metallothioneins and Physiological and Pathological Consequences to Brain Injury

  2004cites this paper
• Methylmercury Differentially Affects GABAA Receptor‐Mediated Spontaneous IPSCs in Purkinje and Granule Cells of Rat Cerebellar Slices

  2003cites this paper
• Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells.

  2002cites this paper
• Mercuric chloride, but not methylmercury, inhibits glutamine synthetase activity in primary cultures of cortical astrocytes.

  2001cites this paper
• Astroglia as metal depots: molecular mechanisms for metal accumulation, storage and release.

  2001cites this paper
• Roles of the metallothionein family of proteins in the central nervous system.

  2001cites this paper
• Methylmercury affects multiple subtypes of calcium channels in rat cerebellar granule cells.

  2000cites this paper
• Methylmercury alters glutamate transport in astrocytes.

  2000cites this paper
• Astrocytes in methylmercury, ammonia, methionine sulfoximine and alcohol-induced neurotoxicity.

  2000cites this paper
• Comparative effects of methylmercury on parallel-fiber and climbing-fiber responses of rat cerebellar slices.

  1999cites this paper
• Methylmercury-induced generation of free radicals: biological implications.

  1999cites this paper
• Glial cells in neurotoxicity development.

  1999cites this paper
• Induction of neuronal nitric oxide synthase by methylmercury in the cerebellum

  1999cites this paper
• Elevations of intracellular Ca2+ as a probable contributor to decreased viability in cerebellar granule cells following acute exposure to methylmercury.

  1998cites this paper
• Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na+ uptake, and K+ release.

  1998cites this paper
• Differential changes in rat brain nitric oxide synthase in vivo and in vitro by methylmercury.

  1998cites this paper
• Pathways mediating Ca2+ entry in rat cerebellar granule cells following in vitro exposure to methyl mercury.

  1997cites this paper
• Characterization of hepatic metallothionein expression in channel catfish (Ictalurus punctatus) by reverse transcriptase polymerase chain reaction.

  1997cites this paper
• Astrocyte Metallothioneins (MTs) and Their Neuroprotective Role a

  1997cites this paper
• Metallothionein induction protects swollen rat primary astrocyte cultures from methylmercury-induced inhibition of regulatory volume decrease.

  1996cites this paper
• Localization of gamma-glutamylcysteine synthetase mRNA expression in mouse brain following methylmercury treatment using reverse transcription in situ PCR amplification.

  1996cites this paper
• Purkinje cells express neuronal nitric oxide synthase after methylmercury administration.

  1996cites this paper