Streptococcus pneumoniae virulence factors and their clinical impact: An update.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Enfermedades Infecciosas y Microbiologia Clinica

• Publication date

  2006-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1157/13092469PMID 16987470
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathogen recognition and innate immunity.

  2006cited by this paper
• Detection of pneumolysin in human urine using an immunosensor on screen-printed carbon electrodes

  2006cited by this paper
• Development of natural antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A and pneumolysin in Filipino pregnant women and their infants in relation to pneumococcal carriage.

  2006cited by this paper
• Review of

  2006cited by this paper
• Multiplex PCR for Identification of Seven Streptococcus pneumoniae Serotypes Targeted by a 7-Valent Conjugate Vaccine

  2005cited by this paper
• Nasal Colonization with Streptococcus pneumoniae Includes Subpopulations of Surface and Invasive Pneumococci

  2005cited by this paper
• Are Anticapsular Antibodies the Primary Mechanism of Protection against Invasive Pneumococcal Disease?

  2005cited by this paper
• Pneumolysin as a vaccine and drug target in the prevention and treatment of invasive pneumococcal disease.

  2005cited by this paper
• Molecular Epidemiology of Macrolide-Resistant Streptococcus pneumoniae Isolates in Europe

  2005cited by this paper
• Antibodies to the Iron Uptake ABC Transporter Lipoproteins PiaA and PiuA Promote Opsonophagocytosis of Streptococcus pneumoniae

  2005cited by this paper
• The role of peptidoglycan in pathogenesis.

  2005cited by this paper
• A molecular-capsular-type prediction system for 90 Streptococcus pneumoniae serotypes using partial cpsA-cpsB sequencing and wzy- or wzx-specific PCR.

  2005cited by this paper
• Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: genetic requirements.

  2005cited by this paper
• Effect of the Seven-Valent Conjugate Pneumococcal Vaccine on Carriage and Drug Resistance of Streptococcus pneumoniae in Healthy Children Attending Day-Care Centers in Lisbon

  2005cited by this paper
• Mucosal Immunity Induced by Pneumococcal Glycoconjugate

  2005cited by this paper
• Illustration of Pneumococcal Polysaccharide Capsule during Adherence and Invasion of Epithelial Cells

  2005cited by this paper
• Diagnosis of Invasive Pneumococcal Infection by Serotype-Specific Urinary Antigen Detection

  2005cited by this paper
• Diagnosis of parapneumonic pleural effusion by polymerase chain reaction in children.

  2005cited by this paper
• A review of vaccine research and development: Human acute respiratory infections

  2005cited by this paper
• Monoacyl Lipoteichoic Acid from Pneumococci Stimulates Human Cells but Not Mouse Cells

  2005cited by this paper
• Loop-Mediated Isothermal Amplification Method Targeting the lytA Gene for Detection of Streptococcus pneumoniae

  2005cited by this paper
• Using Multilocus Sequence Data To Define the Pneumococcus

  2005cited by this paper
• Epidemiological differences among pneumococcal serotypes.

  2005cited by this paper
• Relationship between Surface Accessibility for PpmA, PsaA, and PspA and Antibody-Mediated Immunity to Systemic Infection by Streptococcus pneumoniae

  2005cited by this paper
• Antibodies to the pneumococcal surface protein A, PspA, can be produced in splenectomized and can protect splenectomized mice from infection with Streptococcus pneumoniae.

  2005cited by this paper
• Reduction of antibiotic use in the community reduces the rate of colonization with penicillin G-nonsusceptible Streptococcus pneumoniae.

  2005cited by this paper
• Quantitative PCR Assay Using Sputum Samples for Rapid Diagnosis of Pneumococcal Pneumonia in Adult Emergency Department Patients

  2005cited by this paper
• Differential PsaA-, PspA-, PspC-, and PdB-Specific Immune Responses in a Mouse Model of Pneumococcal Carriage

  2005cited by this paper
• Novel PCR-Restriction Fragment Length Polymorphism Method for Determining Serotypes or Serogroups of Streptococcus pneumoniae Isolates

  2005cited by this paper
• Invasiveness of Serotypes and Clones of Streptococcus pneumoniae among Children in Finland

  2005cited by this paper
• CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization.

  2005cited by this paper
• Streptococcus pneumoniae Antigen Test Using Positive Blood Culture Bottles as an Alternative Method To Diagnose Pneumococcal Bacteremia

  2005cited by this paper
• Genomic Subtraction Followed by Dot Blot Screening of Streptococcus pneumoniae Clinical and Carriage Isolates Identifies Genetic Differences Associated with Strains That Cause Otitis Media

  2005cited by this paper
• Pneumococcal vaccines: an update on current strategies.

  2004cited by this paper
• Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse

  2004cited by this paper
• Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children.

  2004cited by this paper
• Pneumonia in HIV-infected and HIV-uninfected children in developing countries: epidemiology, clinical features, and management

  2004cited by this paper
• Streptococcus pneumoniae in nasopharyngeal secretions of healthy children: comparison of real-time PCR and culture from STGG-transport medium.

  2004cited by this paper
• Immunization with Native or Recombinant Streptococcus pneumoniae Neuraminidase Affords Protection in the Chinchilla Otitis Media Model

  2004cited by this paper
• Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage.

  2004cited by this paper
• A role for Streptococcus pneumoniae in virus-associated pneumonia

  2004cited by this paper
• Simple, Rapid Latex Agglutination Test for Serotyping of Pneumococci (Pneumotest-Latex)

  2004cited by this paper
• Genetic Analysis of Diverse Disease-Causing Pneumococci Indicates High Levels of Diversity within Serotypes and Capsule Switching

  2004cited by this paper
• Protection against Pneumococcal Pneumonia in Mice by Monoclonal Antibodies to Pneumolysin

  2004cited by this paper
• Pneumococcal conjugate vaccines--a European perspective.

  2004cited by this paper
• The innate immune response to pneumococcal lung infection: the untold story.

  2004cited by this paper
• Innate immune recognition of microbes through Nod1 and Nod2: implications for disease.

  2004cited by this paper
• Serum Immunoglobulin G Response to Candidate Vaccine Antigens during Experimental Human Pneumococcal Colonization

  2003cited by this paper
• Anti-PsaA and the risk of pneumococcal AOM and carriage.

  2003cited by this paper
• Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections.

  2003cited by this paper
• Immunodetection of pneumolysin in human urine by ELISA.

  2003cited by this paper
• Evaluation of the polymerase chain reaction method for detection of Streptococcus pneumoniae DNA in pleural fluid samples.

  2002cited by this paper
• Inhibition of pneumococcal carriage in mice by subcutaneous immunization with peptides from the common surface protein pneumococcal surface adhesin a.

  2002cited by this paper
• Cross-Protective Immunity of Mice Induced by Oral Immunization with Pneumococcal Surface Adhesin A Encapsulated in Microspheres

  2002cited by this paper
• Antimicrobial susceptibility and pneumococcal serotypes.

  2002cited by this paper
• Protection against Streptococcus pneumoniae Elicited by Immunization with Pneumolysin and CbpA

  2001cited by this paper
• Intranasal Immunization with Killed Unencapsulated Whole Cells Prevents Colonization and Invasive Disease by Capsulated Pneumococci

  2001cited by this paper
• A SPECIFIC AND ULTRASENSITIVE CHEMILUMINESCENT SANDWICH ELISA TEST FOR THE DETECTION AND QUANTITATION OF PNEUMOLYSIN

  2001cited by this paper
• Pneumococcal Virulence Factors: Structure and Function

  2001cited by this paper
• The Putative Proteinase Maturation Protein A ofStreptococcus pneumoniae Is a Conserved Surface Protein with Potential To Elicit Protective Immune Responses

  2000cited by this paper
• Pneumococcal otitis media and pneumococcal vaccines, a historical perspective.

  2000cited by this paper
• Streptococcus pyogenes resistance to erythromycin in relation to macrolide consumption in Spain (1986-1997).

  2000cited by this paper
• Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules.

  2000cited by this paper
• The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae.

  2000cited by this paper
• Peptide Mimic of Phosphorylcholine, a Dominant Epitope Found on Streptococcus pneumoniae

  2000cited by this paper
• Additive Attenuation of Virulence ofStreptococcus pneumoniae by Mutation of the Genes Encoding Pneumolysin and Other Putative Pneumococcal Virulence Proteins

  2000cited by this paper
• Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and beta-lactam consumption in Spain (1979-1997).

  2000cited by this paper
• Historical Perspective

  2000cited by this paper
• Rapid and Reliable Identification ofStreptococcus pneumoniae Isolates by Pneumolysin-Mediated Agglutination

  1999cited by this paper

• Accurate serotype identification of Streptococcus pneumoniae using nanopore Cas9-targeted serotype identification (nCATSerotyping)

  2025cites this paper
• Lung Organoids from Human Embryonic Stem Cells to Investigate Pneumococcal Serotype 23F that does not Infect Mouse

  2024cites this paper
• Antibody responses after sequential vaccination with PCV13 and PPSV23 in kidney transplant recipients

  2023cites this paper
• The Emergence of Invasive Streptococcus pneumoniae Serotype 24F in Lebanon: Complete Genome Sequencing Reveals High Virulence and Antimicrobial Resistance Characteristics

  2021cites this paper
• Genetic diversity and antigenicity analysis of Streptococcus pneumoniae pneumolysin isolated from children with pneumococcal infection.

  2019cites this paper
• Pneumococcal Predictive Proteins Selected by Microbial Genomic Approach Are Serotype Cross-Reactive and Bind to Host Extracellular Matrix Proteins

  2017cites this paper
• Current Perspectives for Antipneumococcal Vaccination in Patients with Chronic Obstructive Pulmonary Disease

  2016cites this paper
• Theory and strategy for Pneumococcal vaccines in the elderly

  2015cites this paper
• Anti-inflammatory properties of phenolic lactones isolated from Caesalpinia paraguariensis stem bark.

  2013cites this paper
• Pneumococcal polysaccharide vaccination induces polysaccharide-specific B cells in adult peripheral blood expressing CD19⁺CD20⁺CD3⁻CD70⁻CD27⁺IgM⁺CD43⁺CD5⁺/⁻.

  2013cites this paper
• Impact of varying metal ion- and carbohydrate concentrations on gene expression in the human pathogen Streptococcus pneumoniae

  2012cites this paper
• Pneumococcal vaccination among adults with chronic respiratory diseases: a historical overview

  2012cites this paper
• Genome Analysis of a Highly Virulent Serotype 1 Strain of Streptococcus pneumoniae from West Africa

  2012cites this paper
• MOLECULAR EPIDEMIOLOGY OF STREPTOCOCCUS PNEUMONIAE: IMPACT OF PCV7 IN THE PNEUMOCOCCAL POPULATION RESPONSIBLE FOR INVASIVE PEDIATRIC INFECTIONS

  2011cites this paper
• Cloning and optimization of induction conditions for mature PsaA (pneumococcal surface adhesin A) expression in Escherichia coli and recombinant protein stability during long-term storage.

  2011cites this paper
• Structural Basis for the Substrate Specificity of a Novel β-N-Acetylhexosaminidase StrH Protein from Streptococcus pneumoniae R6*

  2011cites this paper
• Cloning and expression of protease ClpP from Streptococcus pneumoniae in Escherichia coli: study of the influence of kanamycin and IPTG concentration on cell growth, recombinant protein production and plasmid stability.

  2011cites this paper
• IN-VITRO AND IN-VIVO EXPRESSION ANALYSIS OF PNEUMOCOCCAL VACCINE CANDIDATES : PILUS-1 COMPONENTS

  2011cites this paper
• The Streptococcus pneumoniae Pilus-1 Displays a Biphasic Expression Pattern

  2011cites this paper
• We should be measuring genomic bacterial load and virulence factors

  2010influential citation
• Analysis of cytoplasmic membrane proteome of Streptococcus pneumoniae by shotgun proteomic approach

  2010cites this paper
• Are there any differences in the community acquired pneumonias admitted to hospital over the past decade?

  2010cites this paper
• Estarão diferentes as pneumonias agudas adquiridas na comunidade com internamento hospitalar em idade pediátrica na última década

  2010cites this paper
• Regulatory responses of Streptococcus pneumoniae to varying metal ion- and nitrogen availability

  2009cites this paper
• [Pneumococcal disease and emergence of serotypes in the vaccine era. Transient trends and serotype replacement?].

  2009cites this paper
• Streptococcus pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight into Substrate-assisted Catalysis in Family 85 Glycoside Hydrolases*

  2009cites this paper
• Enfermedad neumocócica en la era vacunal y emergencia de serotipos. ¿Tendencias temporales y reemplazo de serotipos?

  2009cites this paper
• Cloning, recombinant production, crystallization and preliminary X-ray diffraction analysis of a family 101 glycoside hydrolase from Streptococcus pneumoniae.

  2009cites this paper
• E. Wold Pneumolysin Released During

  2008cites this paper
• Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils

  2008cites this paper
• An easy method for detection of nasopharyngeal carriage of multiple Streptococcus pneumoniae serotypes.

  2008cites this paper
• Rôle du monoxyde d'azote lors d'une pneumonie à pneumocoque. Effet bénéfique du nitroprusside de sodium

  2007influential citation
• Advances in Pneumococcal Vaccines

  2007cites this paper