Mouse colon sensory neurons detect extracellular acidosis via TRPV1.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  2007-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/AJPCELL.00440.2006PMID 17251322
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transient receptor potential vanilloid receptor subtype 1 in painful bladder syndrome and its correlation with pain.

  2006cited by this paper
• Capsaicin receptor (TRPV1) and non-erosive reflux disease

  2006cited by this paper
• Differences in spinal distribution and neurochemical phenotype of colonic afferents in mouse and rat

  2006cited by this paper
• Gastric ulcers evoke hyperexcitability and enhance P2X receptor function in rat gastric sensory neurons.

  2005cited by this paper
• Acid-Sensing Properties in Rat Gastric Sensory Neurons from Normal and Ulcerated Stomach

  2005cited by this paper
• Differential Responses of Bladder Lumbosacral and Thoracolumbar Dorsal Root Ganglion Neurons to Purinergic Agonists, Protons, and Capsaicin

  2005cited by this paper
• The Mechanosensitivity of Mouse Colon Afferent Fibers and Their Sensitization by Inflammatory Mediators Require Transient Receptor Potential Vanilloid 1 and Acid-Sensing Ion Channel 3

  2005cited by this paper
• Jejunal afferent nerve sensitivity in wild‐type and TRPV1 knockout mice

  2004cited by this paper
• Increased expression of TRPV1 receptor in dorsal root ganglia by acid insult of the rat gastric mucosa

  2004cited by this paper
• Proteinase-Activated Receptor 2-Mediated Potentiation of Transient Receptor Potential Vanilloid Subfamily 1 Activity Reveals a Mechanism for Proteinase-Induced Inflammatory Pain

  2004cited by this paper
• Cutaneous and colonic rat DRG neurons differ with respect to both baseline and PGE2-induced changes in passive and active electrophysiological properties.

  2004cited by this paper
• Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice.

  2004cited by this paper
• Neuroanatomy of extrinsic afferents supplying the gastrointestinal tract

  2004cited by this paper
• Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling

  2004cited by this paper
• TRPV1 Function in Mouse Colon Sensory Neurons Is Enhanced by Metabotropic 5-Hydroxytryptamine Receptor Activation

  2004cited by this paper
• Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency.

  2003cited by this paper
• Induction of non‐painful and painful intestinal sensations by hypertonic saline: a new human experimental model

  2003cited by this paper
• PKA/AKAP/VR-1 Module: A Common Link of Gs-Mediated Signaling to Thermal Hyperalgesia

  2002cited by this paper
• Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system

  2002cited by this paper
• Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors.

  2002cited by this paper
• Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia

  2001cited by this paper
• Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

  2001cited by this paper
• Involvement of hypogastric and pelvic nerves for conveying cystitis induced nociception in conscious rats.

  2001cited by this paper
• Toward an Understanding of the Molecules that Sense Myocardial Ischemia

  2001cited by this paper
• Acid-evoked currents in cardiac sensory neurons: A possible mediator of myocardial ischemic sensation.

  1999cited by this paper
• Differential Expression of the mRNA for the Vanilloid Receptor Subtype 1 in Cells of the Adult Rat Dorsal Root and Nodose Ganglia and Its Downregulation by Axotomy

  1999cited by this paper
• Tissue and intracellular pH in normal periarticular soft tissue and during different phases of antigen induced arthritis in the rat.

  1999cited by this paper
• Role of protons in activation of cardiac sympathetic C‐fibre afferents during ischaemia in cats

  1999cited by this paper
• H+‐Gated Cation Channelsa

  1999cited by this paper
• Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves.

  1998cited by this paper
• The cloned capsaicin receptor integrates multiple pain-producing stimuli.

  1998cited by this paper
• The capsaicin receptor: a heat-activated ion channel in the pain pathway

  1997cited by this paper
• Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor

  1997cited by this paper
• TASK, a human background K+ channel to sense external pH variations near physiological pH

  1997cited by this paper
• Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?

  1996cited by this paper
• Differential expression of c-fos and c-jun in two regions of the rat spinal cord following noxious colorectal distention.

  1993cited by this paper

• Transient Receptor Potential channels (TRP) in GtoPdb v.2025.4

  2025cites this paper
• Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients

  2023cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2023.1

  2023cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2023.2

  2023cites this paper
• TRPV1 inactivation alters core body temperature and serum corticosterone levels: Impacts on clock genes expression in the liver and adrenal glands.

  2023cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2022.1

  2022cites this paper
• Members of the CUGBP Elav-Like Family of RNA-Binding Proteins are Expressed in Distinct Populations of Primary Sensory Neurons

  2021cites this paper
• Differential Expression of Acid – Sensing Ion Channels in Mouse Primary Afferents in Naïve and Injured Conditions

  2020cites this paper
• Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves

  2019cites this paper
• TRP channel functions in the gastrointestinal tract

  2016cites this paper
• Identification of different functional types of spinal afferent neurons innervating the mouse large intestine using a novel CGRPα transgenic reporter mouse.

  2016cites this paper
• Physiology of Visceral Pain.

  2016cites this paper
• Mechanosensory Signaling in Enterochromaffin Cells and 5-HT Release: Potential Implications for Gut Inflammation

  2016cites this paper
• Acid-sensing ion channels in gastrointestinal function.

  2015cites this paper
• Mechanism and role of calcium in excitation-mucus secretion coupling in human colonic epithelium

  2015cites this paper
• The Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulators

  2015cites this paper
• CAPSAZEPINE ATTENUATES CANCER-INDUCED BONE PAIN BY INHIBITING GLUTAMATE RELEASE

  2014cites this paper
• 245 Effects of Acid on Vagal Nociceptive Afferent Subtypes in Guinea Pig Esophagus

  2014cites this paper
• Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus.

  2014cites this paper
• Transient Receptor Potential Channels as Drug Targets: From the Science of Basic Research to the Art of Medicine

  2014cites this paper
• TRPV1: A Potential Drug Target for Treating Various Diseases

  2014cites this paper
• Peripheral contribution of NGF and ASIC1a to colonic hypersensitivity in a rat model of irritable bowel syndrome

  2013cites this paper
• VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review

  2013cites this paper
• Effect of Deep Tissue Incision on pH Responses of Afferent Fibers and Dorsal Root Ganglia Innervating Muscle

  2013cites this paper
• Neurosensory mechanotransduction through acid-sensing ion channels

  2013cites this paper
• TRP channels and pain.

  2013cites this paper
• Targeting ASIC3 for pain, anxiety, and insulin resistance.

  2012cites this paper
• Luminal hypertonicity and acidity modulate colorectal afferents and induce persistent visceral hypersensitivity.

  2012cites this paper
• Proton-gated ion channels in mouse bone marrow stromal cells.

  2012cites this paper
• The biophysical and molecular basis of TRPV1 proton gating

  2011cites this paper
• Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

  2011cites this paper
• Acid sensing by visceral afferent neurones

  2011cites this paper
• Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum

  2011cites this paper
• Role of TRP Channels in Pain: An Overview

  2010cites this paper
• Visceral afferents - determinants and modulation of excitability.

  2010cites this paper
• Acid‐induced CGRP release from the stomach does not depend on TRPV1 or ASIC3

  2010cites this paper
• Myalgia and Fatigue: Translation from Mouse Sensory Neurons to Fibromyalgia and Chronic Fatigue Syndromes

  2010cites this paper
• Étude de l'implication du Nerve Growth Factor et des Acid-Sensing Ion Channels dans l'hypersensibilité colique induite par le butyrate chez le rat

  2010cites this paper
• Role of Transient Receptor Potential and Acid-sensing Ion Channels in Peripheral Inflammatory Pain

  2010cites this paper
• Contributions of Different Modes of TRPV1 Activation to TRPV1 Antagonist-Induced Hyperthermia

  2010cites this paper
• Plasma microRNAs: a potential biomarker for colorectal cancer?

  2009cites this paper
• Differences in post-inflammatory hypersensitivity between splanchnic and pelvic afferents: mechanisms and implications for human disease

  2009cites this paper
• Involvement of the transient receptor potential vanilloid 1 (TRPV1) in the development of acute visceral hyperalgesia during colorectal distension in rats.

  2009cites this paper
• TRP channels and pain.

  2009cites this paper
• TRPV1 Expression Defines Functionally Distinct Pelvic Colon Afferents

  2009cites this paper
• Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects.

  2009cites this paper
• Acid-sensitive ion channels and receptors.

  2009influential citation
• Purinergic mechanosensory transduction and visceral pain

  2009cites this paper
• Extrinsic afferent nerve sensitivity and enteric neurotransmission in murine jejunum in vitro.

  2009cites this paper
• The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction.

  2009cites this paper
• Cyclophosphamide-induced bladder inflammation sensitizes and enhances P2X receptor function in rat bladder sensory neurons.

  2008cites this paper
• Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat

  2008cites this paper
• The pharmacological challenge to tame the transient receptor potential vanilloid‐1 (TRPV1) nocisensor

  2008cites this paper
• TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.

  2008cites this paper
• 5.37 – Visceral Pain

  2008cites this paper
• Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.

  2008cites this paper
• The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept

  2007cites this paper